| Vanderbilt University Medical Center | $1,780,114 | 2 | 2024–2025 |
| National Fish and Wildlife Foundation | $1,691,951 | 2 | 2024–2025 |
| The Scripps Research Institute | $1,691,468 | 1 | 2024 |
| Yale University | $1,639,496 | 2 | 2024–2025 |
| Seattle Children's Hospital | $1,549,166 | 2 | 2024–2025 |
| Association of Universities for Research in Astronomy Inc | $1,252,035 | 2 | 2024–2025 |
| The Trustees of Columbia University in the City of New York | $1,237,000 | 2 | 2024–2025 |
| Northeastern University | $1,103,639 | 2 | 2024–2025 |
| The Michael J Fox Foundation for Parkinson's Research | $1,016,669 | 2 | 2024–2025 |
| Alpha-1 Foundation Inc | $994,366 | 2 | 2024–2025 |
| Mayo Clinic Group Return | $946,634 | 1 | 2024 |
| The Nature Conservancy | $801,902 | 2 | 2024–2025 |
| Alzheimer's Disease & Related Disorders Association Inc | $797,371 | 2 | 2024–2025 |
| Carnegie Mellon University | $722,661 | 1 | 2025 |
| President and Fellows of Harvard College | $698,090 | 1 | 2025 |
| The Medical College of Wisconsin Inc | $619,955 | 1 | 2025 |
| The V Foundation | $600,000 | 1 | 2025 |
| Mayo Clinic | $593,366 | 1 | 2024 |
| Lutheran Services Florida Inc | $535,070 | 1 | 2025 |
| Washington University | $437,254 | 1 | 2025 |
| North Central Florida Health Planning CO | $378,503 | 1 | 2025 |
| Hispanic Scholarship Fund | $377,685 | 2 | 2025–2026 |
| Florida Network of Children's Advocacy Centers Inc | $351,715 | 1 | 2025 |
| Trustees of Boston University | $346,009 | 1 | 2025 |
| Parkinson's Foundation Inc | $321,626 | 5 | 2025 |
| The George Washington University | $319,427 | 1 | 2025 |
| Florida Developmental Disabilities Council Inc | $293,609 | 1 | 2025 |
| The Parent Project for Muscular Dystrophy Research Inc | $264,875 | 2 | 2025 |
| International Fresh Produce Association | $263,314 | 4 | 2025 |
| Vanderbilt University | $260,977 | 1 | 2025 |
| The Children's Hospital of Philadelphia | $255,490 | 1 | 2025 |
| American Kennel Club Canine Health Foundation | $239,030 | 1 | 2025 |
| World Resources Institute | $224,475 | 1 | 2025 |
| Alexs Lemonade Stand Foundation | $214,401 | 1 | 2025 |
| Worcester Polytechnic Institute | $201,728 | 1 | 2025 |
| St Baldrick's Foundation Inc | $200,000 | 1 | 2025 |
| Muscular Dystrophy Association Inc | $191,500 | 1 | 2025 |
| American Council of Learned Societies | $149,940 | 1 | 2025 |
| Amyotrophic Lateral Sclerosis Assn | $138,911 | 2 | 2025 |
| Mary Hitchcock Memorial Hospital | $126,089 | 2 | 2025 |
| Rheumatology Research Foundation | $125,000 | 1 | 2025 |
| National 4-H Council | $122,950 | 1 | 2025 |
| Florida 4-H Club Foundation Inc | $120,000 | 1 | 2025 |
| University of Notre Dame du Lac | $108,716 | 1 | 2025 |
| Mission MSA | $105,869 | 1 | 2025 |
| Community Foundation of Tampa Bay Inc | $103,410 | 1 | 2025 |
| United Mitochondrial Disease Foundation Inc | $100,000 | 1 | 2025 |
| Florida Breast Cancer Coalition Research Foundation Inc | $99,761 | 1 | 2025 |
| Seti Institute | $97,360 | 1 | 2025 |
| Pacific Institute for Research and Evaluation | $97,037 | 1 | 2025 |
| I Heermann Anesthesia Foundation Inc | $84,002 | 1 | 2025 |
| Folds of Honor Foundation | $82,943 | 1 | 2025 |
| Wake Forest University | $81,415 | 1 | 2025 |
| National Horticulture Foundation Inc | $80,194 | 2 | 2025 |
| Nova Southeastern University Inc | $76,500 | 1 | 2025 |
| National Public Radio Inc | $69,611 | 1 | 2025 |
| Boston Medical Center Corporation | $68,286 | 1 | 2025 |
| National Multiple Sclerosis Society | $66,844 | 1 | 2025 |
| National Pediatric Cancer Foundation Inc | $64,417 | 1 | 2025 |
| Research Foundation of the City University of New York | $62,684 | 1 | 2025 |
| Lewy Body Dementia Association Inc | $62,500 | 2 | 2025 |
| Temple University - of the Commonwealth System of Higher Education | $60,883 | 1 | 2025 |
| Dialysis Clinic Inc | $50,527 | 1 | 2025 |
| Edwin J Beccue Memorial Foundation Trust | $50,000 | 1 | 2026 |
| National Defense Industrial Association | $50,000 | 1 | 2025 |
| Trustees of Boston College | $49,582 | 1 | 2025 |
| Magee-Womens Research Institute and Foundation | $48,218 | 1 | 2025 |
| The Oaks Women's Club Inc | $47,000 | 2 | 2025–2026 |
| Drexel University | $46,226 | 1 | 2025 |
| Dartmouth-Hitchcock Clinic | $44,301 | 2 | 2025 |
| The Children's Oncology Group Foundation Inc | $43,350 | 1 | 2025 |
| Thomas Jefferson University | $42,755 | 1 | 2025 |
| University of Florida Medical Guild of Gainesville | $42,500 | 1 | 2025 |
| Forging Industry Educational and Research Foundation | $42,282 | 1 | 2025 |
| National Ataxia Foundation Incorporated | $40,653 | 1 | 2025 |
| Health Effects Institute | $40,651 | 1 | 2025 |
| Florida Association of Realtors Education Foundation | $37,800 | 1 | 2025 |
| The Michael and Phyllis Warren Family | $36,000 | 2 | 2025 |
| The Israel Institute Inc | $35,400 | 1 | 2025 |
| Wanda and Janice Wilson Foundation Inc | $31,414 | 1 | 2025 |
| Brown University | $30,543 | 1 | 2025 |
| Florida Medical Schools Quality Network Inc | $30,088 | 1 | 2025 |
| Lifelink Legacy Fund | $30,000 | 1 | 2025 |
| National Science Teaching Association | $29,600 | 1 | 2025 |
| Escambia County 4-H Foundation Inc | $29,388 | 1 | 2025 |
| NCEES Foundation | $28,218 | 1 | 2025 |
| American Floral Endowment | $27,914 | 1 | 2025 |
| Huntington's Disease Society of America Inc | $27,250 | 1 | 2025 |
| Southeast Coastal Ocean Observing Regional Association | $26,655 | 1 | 2025 |
| Petsmart Charities Inc | $25,000 | 1 | 2026 |
| The Brothers' Project Inc | $25,000 | 1 | 2025 |
| National Collegiate Athletic Association | $22,521 | 1 | 2025 |
| Community Foundation of Orange and Sulli | $22,500 | 1 | 2025 |
| The Foundation for the Horse FKA the Aaep Foundation Inc | $20,000 | 1 | 2025 |
| Fred Hutchinson Cancer Center | $15,877 | 1 | 2025 |
| National Philanthropic Trust | $15,610 | 1 | 2025 |
| Society for Conservation Biology | $14,868 | 1 | 2025 |
| Universities Research Association Inc | $13,458 | 1 | 2025 |
| The Jack Miller Center for Teaching America's Founding Principles and | $13,000 | 1 | 2025 |
| Georgetown University | $12,096 | 1 | 2025 |
| American Association of Colleges of Nursing | $12,000 | 1 | 2025 |
| American Quarter Horse Foundation | $10,209 | 1 | 2025 |
| The Foundation for Lee County Public Schools Inc | $10,137 | 1 | 2025 |
| American Cancer Society Inc | $10,000 | 1 | 2025 |
| Debbie-Rand Memorial Service League Inc | $10,000 | 1 | 2025 |
| Harley Langdale Jr Foundation Inc | $9,610 | 1 | 2025 |
| Battier Take Charge Foundation | $9,066 | 1 | 2025 |
| Forest Landowners Association Inc | $7,802 | 1 | 2025 |
| U S Poultry & Egg Harold E Ford Foundation Inc | $7,000 | 1 | 2025 |
| Hearing the Ovarian Cancer Whisper Inc | $6,000 | 1 | 2025 |
| Woodwell Climate Research Center Inc | $5,602 | 1 | 2025 |
| The Cotton Foundation | $5,000 | 1 | 2025 |
| June B Gelbart Foundation | $2,000 | 1 | 2025 |
| Jessie Ball Dupont Scholarship | $1,075 | 1 | 2025 |