| Brown University | $1,314,562 | 2 | 2025 |
| The Children's Hospital of Philadelphia | $1,139,273 | 2 | 2025 |
| Veterans Health Foundation | $1,017,708 | 1 | 2025 |
| Cedar Street Charitable Foundation Inc | $993,199 | 1 | 2025 |
| Beth Israel Deaconess Medical Center Inc | $985,708 | 1 | 2025 |
| Wellcome Leap Inc | $951,639 | 1 | 2025 |
| Institute of International Education Inc | $848,950 | 1 | 2025 |
| National Philanthropic Trust | $804,750 | 1 | 2025 |
| The V Foundation | $800,000 | 1 | 2025 |
| Alzheimer's Disease & Related Disorders Association Inc | $725,745 | 1 | 2025 |
| The George Washington University | $676,295 | 1 | 2025 |
| Fred Hutchinson Cancer Center | $610,773 | 1 | 2025 |
| Good Ventures Foundation | $500,000 | 1 | 2025 |
| Trustees of Tufts College | $464,059 | 1 | 2025 |
| Breakthrough T1D | $449,999 | 1 | 2025 |
| The Chicago Community Trust | $420,352 | 1 | 2025 |
| The Rita and Burt Tansky Foundation | $375,000 | 1 | 2025 |
| The Foundation Fighting Blindness Inc | $375,000 | 1 | 2025 |
| The Mascaro Family Foundation | $375,000 | 3 | 2025 |
| Boston Medical Center Corporation | $372,319 | 1 | 2025 |
| Gismondi Family Foundation Co Mr John | $346,500 | 2 | 2025 |
| Association of Universities for Research in Astronomy Inc | $343,854 | 1 | 2025 |
| Innovatepgh Partnership | $341,544 | 1 | 2025 |
| B K Simon Family Charitable Fdn-Tr | $330,000 | 1 | 2025 |
| Persimmon Foundation | $330,000 | 1 | 2025 |
| Academyhealth | $311,597 | 1 | 2025 |
| The Susan G Komen Breast Cancer Foundation Inc | $300,000 | 1 | 2025 |
| Trustees of Boston University | $282,505 | 1 | 2025 |
| Wings for Life USA - Spinal Cord Research Foundation Inc | $280,000 | 1 | 2025 |
| McElhattan Foundation | $260,000 | 2 | 2025 |
| Pittsburgh Cure Sarcoma | $255,250 | 1 | 2025 |
| American Foundation for Suicide Prevention | $252,500 | 3 | 2025 |
| Health Resources in Action Inc | $250,000 | 1 | 2025 |
| The Chatham Foundation | $250,000 | 1 | 2025 |
| Parker Institute for Cancer Immunotherapy | $249,999 | 1 | 2025 |
| American Parkinson Disease Assoc | $245,000 | 1 | 2025 |
| The Leona M and Harry B Helmsley | $237,102 | 1 | 2025 |
| The Ayco Charitable Foundation | $231,000 | 1 | 2025 |
| Anne G Carson Charitable Trust | $223,738 | 1 | 2025 |
| The Morris and Gertrude Harris Foundatio | $221,764 | 1 | 2025 |
| NCMIC Foundation Inc | $221,500 | 1 | 2025 |
| Seattle Children's Hospital | $220,860 | 1 | 2025 |
| The Frank Calandra Jr Foundation | $220,000 | 1 | 2025 |
| Good Science Project | $218,460 | 1 | 2025 |
| University of Notre Dame du Lac | $218,262 | 1 | 2025 |
| John Nesbit Rees & Sarah Henne Rees Charitable Fou | $216,667 | 2 | 2025 |
| University of Miami | $215,446 | 1 | 2025 |
| Edward P Evans Foundation | $200,000 | 1 | 2025 |
| The David and June Trone Family | $200,000 | 1 | 2025 |
| Whitehall Foundation Inc | $200,000 | 2 | 2025 |
| Brightfocus Foundation | $199,724 | 1 | 2025 |
| National Multiple Sclerosis Society | $192,708 | 1 | 2025 |
| Alexs Lemonade Stand Foundation | $190,000 | 1 | 2025 |
| Mukaiyama Rice Foundation | $190,000 | 1 | 2025 |
| Johnstown Educational Foundation | $182,818 | 1 | 2025 |
| Pennsylvania Interest on Lawyer Trust Accounts Board | $177,800 | 1 | 2025 |
| Scleroderma Research Foundation | $176,500 | 1 | 2025 |
| Temple University - of the Commonwealth System of Higher Education | $175,733 | 1 | 2025 |
| Rheumatology Research Foundation | $175,000 | 2 | 2025 |
| Edgar Levenson Trust | $162,042 | 1 | 2025 |
| Vanderbilt University | $156,246 | 1 | 2025 |
| Emergency Medicine Foundation | $150,000 | 1 | 2025 |
| Parkinson's Foundation Inc | $150,000 | 1 | 2025 |
| Leukemia Research Foundation | $150,000 | 1 | 2025 |
| Sam Day Foundation | $150,000 | 1 | 2025 |
| The Goldman Sachs Charitable Gift Fund | $150,000 | 1 | 2025 |
| Critical Path Institute | $145,000 | 1 | 2025 |
| Drexel University | $144,338 | 1 | 2025 |
| Benaroya Research Institute at Virginia | $140,160 | 1 | 2025 |
| Owens Samuel T Jr Decd | $135,000 | 1 | 2025 |
| The Spencer Foundation | $134,529 | 1 | 2025 |
| The Blackbaud Giving Fund | $129,565 | 1 | 2025 |
| The Arlyn Gilboa Foundation | $127,000 | 1 | 2025 |
| Target ALS Foundation Inc | $125,000 | 1 | 2025 |
| Arthritis National Research Foundation | $125,000 | 1 | 2025 |
| The United Way of Southwestern Pennsylvania | $123,688 | 1 | 2025 |
| Blood Cancer United Inc | $120,000 | 1 | 2025 |
| Hispanic Scholarship Fund | $119,603 | 1 | 2026 |
| The Commonwealth Fund | $115,487 | 1 | 2025 |
| Russell Sage Foundation | $114,705 | 2 | 2025 |
| Research Foundation of the City University of New York | $112,230 | 1 | 2025 |
| American Epilepsy Society | $108,494 | 1 | 2025 |
| The Nancy Taylor Foundation | $108,000 | 1 | 2025 |
| The Mattei-Rothschild Foundation Inc | $102,496 | 1 | 2025 |
| Alzheimer's Disease Research Foundation | $100,625 | 1 | 2025 |
| Hearing Health Foundation | $100,000 | 1 | 2025 |
| The Vision of Children | $100,000 | 1 | 2025 |
| Paralyzed Veterans of America | $100,000 | 1 | 2025 |
| The Earl and Anna Broady Foundation | $100,000 | 1 | 2025 |
| Charities Aid Foundation America | $99,230 | 1 | 2025 |
| Pennsylvania Center for Poultry and Livestock Excellence | $98,038 | 1 | 2025 |
| American Orthopaedic Society for Sports Medicine | $96,000 | 1 | 2025 |
| The Medical College of Wisconsin Inc | $95,433 | 1 | 2025 |
| Reinecke Family Charitable Foundation | $95,000 | 1 | 2025 |
| Lupus Research Alliance Inc | $93,029 | 1 | 2025 |
| Raymond James Charitable Endowment Fund | $92,700 | 1 | 2025 |
| Jewish Federation of Greater Pittsburgh | $92,136 | 1 | 2025 |
| Dystonia Medical Research Foundation | $91,956 | 1 | 2025 |
| The Children's Oncology Group Foundation Inc | $88,350 | 1 | 2025 |
| James T and Rose M Perryman Family Foundation | $86,200 | 1 | 2025 |
| Samuel & Emma Winters Foundation | $85,299 | 1 | 2025 |
| West Virginia University Research Corporation | $82,481 | 1 | 2025 |
| NMDP Foundation | $80,000 | 1 | 2025 |
| Jefferson Regional Foundation | $80,000 | 1 | 2025 |
| American Council of Learned Societies | $79,500 | 1 | 2025 |
| Ethel Vincent Charitable Trust | $76,410 | 1 | 2025 |
| T Rowe Price Program for Charitable Giving Inc | $76,050 | 2 | 2025–2026 |
| National Fish and Wildlife Foundation | $75,532 | 1 | 2025 |
| James & Noel Browne Charitable Trust | $75,000 | 1 | 2025 |
| Sarcoma Foundation of America | $75,000 | 1 | 2025 |
| The Frazier Foundation | $75,000 | 1 | 2025 |
| Society of Family Planning | $75,000 | 1 | 2025 |
| John B and Jarmila Maiorana Fdn | $73,086 | 1 | 2025 |
| Boomer Esiason Foundation | $71,332 | 1 | 2025 |
| Neighborhood Allies Inc | $70,750 | 1 | 2025 |
| Rike Paul for Univ PGH SCHL Med-Tr | $70,000 | 1 | 2025 |
| Wittmer Zoerb Foundation | $70,000 | 1 | 2025 |
| Louise & Ferdinand Mulert Fund | $69,588 | 1 | 2025 |
| Morris J for Clark Med Ed Fdn | $66,000 | 1 | 2025 |
| Ernst & Young Foundation | $65,000 | 1 | 2025 |
| Melanoma Tissue Bank Consortium | $63,500 | 1 | 2025 |
| Focused Ultrasound Foundation | $62,500 | 1 | 2025 |
| The Orau Foundation | $60,540 | 1 | 2025 |
| Puri Family Giving Fund | $60,000 | 1 | 2025 |
| Neurosurgery Research and Education Foundation | $60,000 | 1 | 2025 |
| Dickson J Z & Agnes F-Dickson Prizes | $57,721 | 1 | 2025 |
| The Israel Institute Inc | $56,000 | 1 | 2025 |
| The Scripps Research Institute | $52,486 | 1 | 2025 |
| Futures Without Violence | $51,214 | 1 | 2025 |
| The Children's Mercy Hospital | $50,307 | 1 | 2025 |
| Aldrich Foundation | $50,000 | 1 | 2025 |
| The Pruina Corporation | $50,000 | 1 | 2025 |
| Management as a Liberal Art Foundation | $50,000 | 1 | 2025 |
| The Klingenstein Third Generation Foundation | $50,000 | 1 | 2025 |
| Resources for the Future Inc | $50,000 | 1 | 2025 |
| Michael and Suellen Weir Foundation Inc | $50,000 | 1 | 2025 |
| Sleep Research Society Foundation (SRSF) | $50,000 | 1 | 2025 |
| Donaldson H-Pitt Sch Soc Work | $49,018 | 1 | 2025 |
| Community Foundation of Greater Johnstown | $48,260 | 1 | 2025 |
| Folds of Honor Foundation | $47,250 | 1 | 2025 |
| Vartabedian Family Foundation | $46,800 | 1 | 2025 |
| Rodgers H for U of P & P a B | $45,854 | 1 | 2025 |
| Jumpstart for Young Children Inc | $43,874 | 1 | 2025 |
| Rensselaer Polytechnic Institute | $43,585 | 1 | 2025 |
| Miller K a for Univ of PGH | $42,500 | 1 | 2025 |
| Health and Welfare Foundation of | $42,000 | 1 | 2025 |
| Mary Hitchcock Memorial Hospital | $40,174 | 1 | 2025 |
| Fisa Foundation | $40,000 | 1 | 2025 |
| The Society for Analytical Chemists of | $40,000 | 1 | 2025 |
| Charles F Spang Foundation | $38,444 | 1 | 2025 |
| The Masonic Foundation of the District | $10,000 | 1 | 2026 |
| Eric and Tiffany Friedman Foundation | $10,000 | 1 | 2026 |
| Shoreview and Sugar Land Foundation | $10,000 | 1 | 2026 |
| Neavitt-Thomas Endowment Fund Tr XXXXX3002 | $8,551 | 1 | 2026 |
| M Verna Butterer Educational Trust | $8,162 | 1 | 2026 |
| Hammers C a & E W Char Ta | $8,000 | 1 | 2026 |
| Paul O & Mary Boghossian | $3,000 | 1 | 2026 |
| Marguerite Carl Smith Foundation 230004 | $2,500 | 1 | 2026 |
| The S Wilson and Grace M Pollock Foundation | $1,000 | 1 | 2026 |