Alzheimer's Disease Research Foundation logo

Alzheimer's Disease Research Foundation

WELLESLEY HILLS, MA EIN: 52-2396428 Website

Alzheimer's Disease Research Foundation, operating as Cure Alzheimer's Fund (CureAlz), is a 501(c)(3) nonprofit organization headquartered in Wellesley Hills, Massachusetts. Established in 2004, the organization is dedicated to funding research with the highest probability of slowing, stopping, or reversing Alzheimer's disease. The foundation has distributed over $200 million in research grants since its inception and maintains a 36-person staff.

Financial Overview

From 2024 IRS Form 990-PF · View filing

Total Assets

$28.6M

-14.6% YoY

Annual Giving

$24.4M

+5.6% YoY

Grant Count

106

+8.2% YoY

Avg Grant Size

$230K

-2.4% YoY

Research compiled by Grantable AI from public sources. Last updated April 2026.

Mission & Focus Areas

Mission: To fund research with the highest probability of slowing, stopping, or reversing Alzheimer's disease.

Primary Research Areas:

  • Alzheimer's Genome Project™
  • Genes to Therapy / Stem Cell Screening
  • Identification of disease mechanisms
  • Immune System Structures & Processes
  • Interaction of the Microbiome
  • Pathological Pathways & Systems

The organization supports research across multiple disease understanding domains, including investigations into genetic factors, the role of the gut microbiome and immune system in brain health, and novel prevention and treatment approaches.

Grantmaking

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Geographic Focus

Where this funder awards grants

The foundation funds research internationally, with active grantmaking in:

  • United States
  • United Kingdom
  • Germany
  • Israel

Grant Distribution by State

22states
+14 more states

Cities

Ann ArborAtlantaBaltimoreBethesdaBloomingtonBostonBronxCambridgeChapel HillCharlestownCharlottesvilleChicagoDallasDavisDurhamEvanstonFarmingtonHoustonIrvineJacksonville

Financial History

Multi-year comparison from IRS filings

As of 2023 Tax Filing:

  • Total Assets: $33,488,279
  • Total Revenue: $37,725,207
  • Total Giving/Expenses: $34,633,548
  • Total Liabilities: $1,730,000

Historical Milestones:

  • 2021: Surpassed $125 million in cumulative research funding
  • 2022: Raised $32 million in contributions (14% increase from 2021), received support from nearly 24,000 donors
Revenue
Expenses
Qualifying Distributions
Net Investment Income
$0$11M$22M$34M$45M20202021202220232024
Metric202420232022
Total Assets$28,586,231$33,488,279$30,192,784
Revenue$31,755,677$37,725,207$40,708,245
Expenses$36,999,068$34,633,548$30,613,014
Qualifying Distributions
Net Investment Income$964,653$1,042,285$8,359,727
Distributable Amount

Giving Over Time

Total grant dollars and number of grants per year

$0$6M$12M$18M$24M47 grants202076 grants202185 grants202298 grants2023106 grants2024

Grant Insights

How this funder distributes its grants

Top Recipients

Top 10 recipients in 2024

MASSACHUSETTS GENERAL HO…$2.0MBRIGHAM AND WOMEN'S HOSP…$575KMASSACHUSETTS GENERAL HO…$300KMASSACHUSETTS INSTITUTE …$300KMASSACHUSETTS GENERAL HO…$288KMASSACHUSETTS GENERAL HO…$288KMASSACHUSETTS GENERAL HO…$288KNATIONAL INSTITUTE OF NE…$288KBRIGHAM AND WOMEN'S HOSP…$276KDUKE UNIVERSITY SCHOOL O…$269K

Grant Size Distribution

247 grants across all recorded years

7<$50K5$50–100K171$100–250K57$250–500K3$500K–1M4$1–5M$5M+

Giving History

Grant recipients and amounts by year

No grants recorded for .

Leadership & Key People

Leadership team and compensation from IRS filings

Chief Executive Officer: Tim Armour (as of 2023)

Chief Executive Officer: Margaret Smith (as of October 2023)

Compensation Overview

From 2024 IRS filing

MARGARET E SMITHCEO$426KKATHARINE HERMANEVP DEVELOPMENT$419KJULIE HARRISEVP RESEARCH MGMT (TO 12/24)$296KBARBARA CHAMBERSEVP MARKETING & COMM.$268KJOSEPHINE ANTONELLISCFO$200KLISA RANDVP MARKETING & COMM.$199KJOHN SLATTERYSVP, PHILANTHROPIC PARTNERSH…$199KDANIEL HARPERVP DEVELOPMENT$195KMAHUA DASGUPTASR. PHILANTROPIC ADVISOR$178KTHIDAPHORN SENGSAVANHDIRECTOR OF DEVELOPMENT OPS$154KLAUREL LYLESECRETARY & VP BOARD RELATIO…$121K

From 2024 filing

NameTitleHoursCompensation
MARGARET E SMITHCEO40$426,320
HENRY MCCANCECHAIR5
PHYLLIS RAPPAPORTTREASURER5
TIMOTHY ARMOURDIRECTOR3
RICHARD BIRNBAUMDIRECTOR4
MARK FAGGIANODIRECTOR (FROM 10/24)3
MARY GREENHILL CAGLIERODIRECTOR (FROM 10/24)3
ROBERT GREENHILLDIRECTOR (TO 10/24)3
KUMAR MAHADEVADIRECTOR (FROM 12/24)3
JACQUELINE MORBYDIRECTOR4
JOSEPHINE ANTONELLISCFO30$200,226
LAUREL LYLESECRETARY & VP BOARD RELATIONS & DEV OPS30$121,094
KATHARINE HERMANEVP DEVELOPMENT40$418,581
JULIE HARRISEVP RESEARCH MGMT (TO 12/24)40$296,359
BARBARA CHAMBERSEVP MARKETING & COMM.40$267,548
LISA RANDVP MARKETING & COMM.40$199,320
DANIEL HARPERVP DEVELOPMENT40$195,493
JOHN SLATTERYSVP, PHILANTHROPIC PARTNERSHIPS40$198,792
MAHUA DASGUPTASR. PHILANTROPIC ADVISOR40$178,255
THIDAPHORN SENGSAVANHDIRECTOR OF DEVELOPMENT OPS40$154,055

Recent News & Activity

Recent developments and announcements

2023

**2023:** Cure Alzheimer's Fund announced its 18th consecutive year of record results, with 2022 marking the strongest year in organizational history.

**Recent Achievements:**

Awarded the 1,000th research grant

CURE ALZHEIMER'S FUND AWARDS 1,000TH RESEARCH GRANT

Received a $50 million gift to support research

Cure Alzheimer's Fund Receives $50 Million Gift to Support ...

Launched the Brain Aging Consortium to decode how aging shapes Alzheimer's risk

CURE ALZHEIMER'S FUND LAUNCHES BRAIN AGING ...

**Recognition:**

Maintains a 100% perfect score and Four-Star rating from Charity Navigator for more than 13 consecutive years

Received a Platinum Seal of Transparency

**Notable Research Outcomes:**

The Alzheimer's Genome Project, funded through grants, has revealed four novel sex-specific Alzheimer's disease genes that confer opposite risk impact in men versus women, with variations in three genes increasing AD risk in men while appearing protective in women

CURE ALZHEIMER'S FUND AWARDS 1000TH ...

Subject Areas

Focus areas based on grantmaking activity

Data last updated April 2026. Sourced from IRS Form 990-PF filings. Research dossier generated April 2026.

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