Benaroya Research Institute (BRI) is a nonprofit medical research organization headquartered in Seattle, Washington, affiliated with Virginia Mason Franciscan Health. Established in 1956 as a Virginia Mason research center and formally becoming BRI in 1985, the institute conducts research on diseases and immune disorders, including autoimmune diseases, allergies, asthma, and cancer. BRI employs approximately 320 staff members and operates as a 501(c)(3) organization.
Financial Overview
From 2024 IRS Form 990-PF · View filing
Total Assets
$96.0M
+1.8% YoY
Annual Giving
$36.0M
+22.8% YoY
Grant Count
80
+21.2% YoY
Avg Grant Size
$450K
+1.3% YoY
Mission & Focus Areas
Mission: To advance the science to predict, prevent, reverse and cure diseases of the immune system.
Vision: A healthy immune system for everyone.
BRI's research focuses on understanding the immune system in health and disease, with particular emphasis on:
- Autoimmune diseases
- Allergic diseases and asthma
- Cancer immunology
- Immune-mediated rejection of transplanted organs, tissues, and cells
The institute organizes its work around four Centers of Discovery:
Fundamental Immunology Center (Led by Dan Campbell, PhD) — Investigates cellular and molecular pathways controlling the immune system, focusing on genes, cells and molecules involved in autoimmune and inflammatory diseases.
Translational Immunology Center (Led by Karen Cerosaletti, PhD) — Applies lab discoveries to improve human health and clinical care, studying how existing medicines alter immune response in disease.
Interventional Immunology Center (Led by Cate Speake, PhD) — Uses small and large-scale clinical studies to translate lab discoveries to patient therapies.
Systems Immunology Center (Led by Adam Lacy-Hulbert, PhD) — Analyzes large and complex data sets across all centers to identify patterns and accelerate breakthroughs.
Grantmaking
BRI serves as the prime recipient and administrator of the Immune Tolerance Network (ITN), a research consortium established in 1999. The ITN received initial funding from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) in 2014 and was renewed for a second grant cycle in 2021, providing approximately $27 million annually.
Review Cycle
in 2021, providing approximately $27 million annually.
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Geographic Focus
Where this funder awards grants
BRI is based in Seattle, Washington and operates internationally, with research activities spanning multiple countries including Thailand, Morocco, Canada, and France.
Grant Distribution by State
States
Cities
Financial History
Multi-year comparison from IRS filings
2024 Financial Data:
- Total Revenues: $93,579,246
- Total Expenses: $87,516,122
- Total Assets: $96,038,082
2023 Financial Data:
- Total Revenues: $82.5 million
- Total Expenses: $83.3 million
- Total Assets: $94.4 million
- Total Liabilities: $42.7 million
Organization Rating: BRI holds a Four-Star rating with a 96% overall score based on accountability and finance metrics.
| Metric | 2024 | 2023 | 2022 |
|---|---|---|---|
| Total Assets | $96,038,082 | $94,354,363 | $100,143,058 |
| Revenue | $93,579,246 | $82,465,243 | $94,861,276 |
| Expenses | $87,516,122 | $83,326,987 | $83,785,554 |
| Qualifying Distributions | — | — | — |
| Net Investment Income | $407,521 | $282,812 | $9,899,625 |
| Distributable Amount | — | — | — |
Giving Over Time
Total grant dollars and number of grants per year
Grant Insights
How this funder distributes its grants
Top Recipients
Top 10 recipients in 2024
Grant Size Distribution
250 grants across all recorded years
Giving History
Grant recipients and amounts by year
No grants recorded for .
Leadership & Key People
Leadership team and compensation from IRS filings
- Dr. Jane Buckner — President of BRI; assumed the role of principal investigator for the Immune Tolerance Network grant following the retirement of Dr. Jerry Nepom in 2022.
- Dr. Dan Campbell — Leads the Fundamental Immunology Center
- Dr. Karen Cerosaletti — Leads the Translational Immunology Center
- Dr. Cate Speake — Leads the Interventional Immunology Center
- Dr. Adam Lacy-Hulbert — Leads the Systems Immunology Center
Compensation Overview
From 2024 IRS filing
From 2024 filing
| Name | Title | Hours | Compensation |
|---|---|---|---|
| KETUL PATEL | CHIEF EXECUTIVE OFFICER VMFH | 10 | $2,613,387 |
| JANE BUCKNER MD | PRESIDENT | 40 | $501,678 |
| MARGARET MCCORMICK PHD | EXECUTIVE DIRECTOR & COO | 40 | $303,699 |
| WILLIAM KWOK PHD | RESEARCH MEMBER | 40 | $286,471 |
| DANIEL CAMPBELL PHD | DIRECTOR, CENTER FOR FUNDAMENTAL IMMUNOLOGY | 40 | $230,355 |
| JESSICA HAMERMAN PHD | DIRECTOR, ACADEMIC AFFAIRS | 40 | $229,026 |
| CARMEN MIKACENIC MD | ASSOCIATE RESEARCH MEMBER | 40 | $224,166 |
| PETER LINSLEY PHD | MEMBER, PRINCIPAL INVESTIGATOR | 40 | $220,411 |
| MICHAEL LABOSIER | CFO | 40 | $186,969 |
| CHUCK ARNOLD | DIRECTOR | 2 | — |
| BOB CARLILE | DIRECTOR | 2 | — |
| MIRIAM CHAMBLISS | CORPORATE SECRETARY / VP DIV GENERAL COUNSEL | 2 | — |
| ULI CHI PHD | DIRECTOR/CHAIR | 2 | — |
| SISTER JUDE CONNELLY OSF | DIRECTOR (PARTIAL YEAR) | 2 | — |
| CAROLYN CORVI | DIRECTOR | 2 | — |
| SISTER RUTH GOODWIN OSF | DIRECTOR | 2 | — |
| TOD HAMACHEK | DIRECTOR | 2 | — |
| DENNIS HUNTHAUSEN | DIRECTOR | 2 | — |
| KAREN LEE | DIRECTOR | 2 | — |
| ROBERT LEMON | DIRECTOR/VICE CHAIR | 2 | — |
| GREGG MEYER MD MSC | DIRECTOR | 2 | — |
| DAVID NOSACKA | TREASURER / SVP & CFO VMFH | — | — |
| JOHN OPPENHEIMER | DIRECTOR | 2 | — |
| MARVIN O'QUINN | DIRECTOR (PARTIAL YEAR) | 2 | — |
| DIANN PULS | DIRECTOR | 2 | — |
Recent News & Activity
Recent developments and announcements
BRI continues to expand its research portfolio and collaborative efforts. The institute has received multiple significant NIH grants in recent years, including U19 and R01 awards supporting research in respiratory viral infections and type 1 diabetes treatment development. The organization emphasizes personalized medicine and prevention approaches, with ongoing expansion beyond autoimmune diseases into broader immune system research areas.
Benaroya Research Institute Awarded $13 Million Across 13 Grants in LastSubject Areas
Focus areas based on grantmaking activity
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Data last updated April 2026. Sourced from IRS Form 990-PF filings. Research dossier generated April 2026.
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