Target ALS Foundation Inc
Target ALS Foundation Inc is a private foundation based in New York, NY, that supports ALS research and drug discovery. Founded in 2013, it describes its work as breaking down barriers to research and accelerating the discovery of effective treatments through collaboration across scientific disciplines and research constituencies.
Target ALS Foundation Inc at a glance
In short: Target ALS Foundation Inc gave $10.1M across 47 grants in 2025 (avg $215K), top state California. 53% of 2025 grantees were new. Source: 2025 IRS Form 990.
- Annual giving (2025)
- $10,101,044
- -44.0% vs 2024
- Grants made (2025)
- 47
- -37.3% vs 2024
- Average grant
- $214,916
- -10.7% vs 2024
- Median grant
- $140,000
- Total assets
- $136,912,637
- +6.2% vs 2024
- New grantees (estimate)
- 53% first-time grantees (25 of 47, 2025)
- Primary geography
- California (36% of itemized 2025 grant dollars)
- Latest 990 filing
- Form 990, 2025 View filing
Data from IRS Form 990, 2025; updated September 2026. New grantees are estimated by matching recipient names across years (methodology).
How to apply to Target ALS Foundation Inc
- Accepts unsolicited proposals
- No
- How to Apply
-
The foundation states that it makes contributions only to preselected charitable organizations and does not accept unsolicited requests. Its website also describes specific research funding opportunities, with listed calls marked closed or scheduled to open April 7, 2026.
- Contact
Mailing address: 244 Madison Ave 1025, New York, NY 10016
Phone: (646) 592-2541
Website: https://targetals.org
Application details from Grantable's research on the foundation's public materials; confirm on its website before applying.
Who Target ALS Foundation Inc funds
How this funder distributes its grants
Top Recipients
Top 10 recipients in 2025
The largest 2025 recipient was Dignity Health ($800K). Together the top 10 received $4.9M.
Grant Size Distribution
227 grants across all recorded years
The most common grant size was in the $100–250K range: 119 grants of 227 (52%).
Geographic Focus
Where this funder awards grants
The foundation states that its funding opportunities are open to investigators worldwide. In filing year 2025, the largest shares of grant dollars went to recipients in California (38%), Massachusetts (13%), Florida (7%), Illinois (7%), and New York (6%).
Grant Distribution by State
Share of 2025 grant dollars across all 47 itemized grants.
States
Cities
Is Target ALS Foundation Inc open to new grantees?
53%
first-time grantees, 2025
In 2025, 25 of 47 grantees (53%) were first-time recipients. First grants averaged $228K; repeat grants $199K. How we count
Medians: $200K first-time, $121K repeat.
- 45% of 2025 grantees were also funded in 2024. Method
- Giving grew 66% from 2022 to 2025. Method
- In 2024 it paid out 734% of its IRS minimum distribution (the 5% rule). Method
Estimate from itemized grant lists in IRS Form 990 filings (2019–2025). Recipient names are matched across years, so a renamed or misspelled grantee can look new; grants to individuals are left out. Methodology.
Giving History
Giving Over Time
Total grant dollars and number of grants per year
From 2019 to 2025, annual grant giving ranged from $3.3M (2019) to $18.0M (2024). In 2025 it made 47 grants totaling $10.1M.
Grants by year
Grant recipients and amounts by year
| Recipient | Purpose | Amount |
|---|---|---|
| Dignity Health Phoenix, CA | Scientific Research | $800,313 |
| University of California San Francisco San Francisco, CA | Scientific Research | $731,472 |
| Mayo Clinic Jacksonville South Jacksonville, FL | Scientific Research | $579,510 |
| Columbia University New York, NY | Scientific Research | $575,116 |
| Regents of the University of California at San Diego La Jolla, CA | Scientific Research | $461,402 |
| Northwestern University Chicago, IL | Scientific Research | $438,968 |
| Emory University Atlanta, GA | Scientific Research | $386,594 |
| The Massachusetts General Hospital Boston, MA | Scientific Research | $375,000 |
| The University of Alabama at Birmingham Birmingham, AL | Scientific Research | $298,217 |
| University of California Santa Barbara Santa Barbara, CA | Scientific Research | $290,000 |
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Financial History
Multi-year comparison from IRS filings
| Filing year | Total Assets | Revenue | Expenses | Grants paid | Grants | Qualifying Distributions | Net Investment Income | Distributable Amount |
|---|---|---|---|---|---|---|---|---|
| 2025 | $136,912,637 | $33,261,985 | $25,618,714 | $10,101,044 | 47 | — | $3,535,375 | — |
| 2024 | $128,911,762 | $51,745,776 | $27,108,058 | $18,048,427 | 75 | $27,030,939 | $3,765,775 | $3,680,524 |
| 2023 | $180,572,961 | $79,570,641 | $15,859,537 | $10,709,339 | 47 | $15,856,237 | $407,954 | $7,785,698 |
| 2022 | $115,562,468 | $98,381,069 | $9,271,989 | $6,070,799 | 33 | $9,271,989 | $24,092 | $4,423,430 |
| 2021 | $26,527,264 | $6,977,665 | $7,789,597 | $5,886,581 | 25 | $7,789,697 | $25,055 | $1,115,199 |
| 2020 | $27,026,641 | $27,270,423 | $7,004,450 | $5,041,352 | 27 | — | $18,124 | $1,891,405 |
| 2019 | $5,760,183 | $5,489,621 | $5,462,803 | $3,276,215 | 19 | — | $132,462 | $605,893 |
Research compiled by Grantable AI from public sources. Last updated September 2026.
Mission & Focus Areas
The foundation’s mission is to break down barriers to ALS research to find effective treatments by uniting academia, the pharma and biotech industry, government, venture capital, related nonprofits, and the ALS community.
Its funding opportunities have included collaborative research into ALS biomarkers, in vivo validation of therapeutic targets in mouse models, and consortia studying the fundamental biology of genetic and sporadic ALS. The basic biology call sought multidisciplinary projects investigating disease mechanisms and potential therapeutic targets, including work involving multi-omic approaches and artificial intelligence or machine learning.
Among its 2025 grantees, Northwestern University describes its mission as combining excellent teaching and innovative research with student growth in a diverse academic community. Emory University describes work in education and life-saving medical research. The University of Pittsburgh describes itself as a public research university serving its region, state, and nation through education, research, and community partnership.
Grantmaking
The largest awards included $800,313 to Dignity Health, $731,472 to the University of California San Francisco, $579,510 to Mayo Clinic Jacksonville, and $575,116 to Columbia University; each was designated for scientific research.
Other notable 2025 awards included $461,402 to the Regents of the University of California at San Diego, $438,968 to Northwestern University, $386,594 to Emory University, and $375,000 to the Massachusetts General Hospital.
The foundation’s website lists funding calls for collaborative ALS biomarker consortia, in vivo target validation, and basic biology consortia. The basic biology call specified collaborative teams of three to five laboratories. The in vivo target validation program evaluates investigator-provided test articles in a TDP-43 mouse model; applicants must demonstrate test-article safety at the planned dose and provide brain-penetrance data. The website states that proposals are reviewed by an Independent Review Committee and that the foundation does not seek ownership of resulting intellectual property or financial gains.
Leadership & Key People
Leadership team and compensation from IRS filings
The 2025 filing lists Daniel L. Doctoroff as board chair. Board members listed are John Dunlop, Brad S. Karp, Zach W. Hall, Story Landis, Sarah Sheikh, Alisa Doctoroff, Allison Jaffin, Andy Berndt, and Chris Hernderson.
Target ALS Foundation Inc is led by Manish Raisinghani, President on every filing since 2019; 8 of 22 officers listed in 2025 are compensated.
Officers on the 2025 filing
Manish Raisinghani
President
On filings since 2019
40 hrs/week
$309K (2021) → $404K (2025)
Daniel L. Doctoroff
Board Chair
Board Member → Chair, 2023
Chair → Board Chair, 2025
On filings since 2019
1 hr/week
No compensation reported
Christine Prouty Aranyos
Director of Philanthropy
New on the 2025 filing
40 hrs/week
$165K (2025)
Stephanie Ishoo
Director of Marketing & Communications
New on the 2025 filing
40 hrs/week
$166K (2025)
Kenneth Devaney
Chief Operating Officer
Treasurer → Chief Operating Officer, 2025
On filings since 2019
40 hrs/week
$211K (2021) → $294K (2025)
Amy Easton
Vice President & Research Groups
New on the 2025 filing
40 hrs/week
$300K (2025)
Jessica Chapman
Chief Development Officer
New on the 2025 filing
40 hrs/week
$240K (2025)
Laura Dugom
Associate Director Clinical Research
New on the 2025 filing
40 hrs/week
$169K (2025)
Yuliya Rzad
Chief Grants Officer
New on the 2025 filing
40 hrs/week
$206K (2025)
John Dunlop
Board Member
On filings since 2019
1 hr/week
No compensation reported
Story Landis
Board Member
On filings since 2019
1 hr/week
No compensation reported
Zach W. Hall
Board Member
On filings since 2019
1 hr/week
No compensation reported
Carol Ho
Board Member
On filings since 2020
1 hr/week
No compensation reported
Richard Hargreaves
Board Member
On filings since 2020
1 hr/week
No compensation reported
Alisa Doctoroff
Board Member
On filings since 2022
1 hr/week
No compensation reported
Sarah Sheikh
Board Member
On filings since 2022
1 hr/week
No compensation reported
Brad S. Karp
Board Member
On filings since 2023
1 hr/week
No compensation reported
Allison Jaffin
Board Member
On filings since 2024
1 hr/week
No compensation reported
Andy Berndt
Board Member
On filings since 2024
1 hr/week
No compensation reported
Chris Hernderson
Board Member
On filings since 2024
1 hr/week
No compensation reported
Eric Dane
Board Member
New on the 2025 filing
1 hr/week
No compensation reported
Stacy Weninger
Board Member
New on the 2025 filing
1 hr/week
No compensation reported
Former officers (4)
- Former: Stacie Weninger (2020–2024) — Board Member
- Former: Mike Poole (2019–2023) — Board Member
- Former: Jeffrey D. Rothstein (2019–2020) — Board Member
- Former: Kevin Eggan (2019–2020) — Board Member
Data from IRS Form 990 filings, 2019–2025. "On filings since" is the earliest filing we hold that lists the person; hours are average hours per week as reported.
Compensation Overview
From 2025 IRS filing
The highest reported compensation on the 2025 filing was $404K, to Manish Raisinghani (President). 8 officers or directors reported compensation on that filing.
Frequently asked questions about Target ALS Foundation Inc
How much does Target ALS Foundation Inc give each year?
Target ALS Foundation Inc gave $10.1M across 47 grants in 2025, according to its 2025 IRS Form 990. In 2024 it gave $18.0M across 75 grants.
What is Target ALS Foundation Inc's typical grant size?
Target ALS Foundation Inc's median grant in 2025 was $140,000, and its average grant was $214,916, across 47 grants on its 2025 IRS Form 990. Organizations receiving their first grant from Target ALS Foundation Inc that year got $228K on average.
Where does Target ALS Foundation Inc give grants?
Target ALS Foundation Inc's top state is California, with 36% of the grant dollars itemized on its 2025 IRS Form 990. The next largest states were Massachusetts (14%) and Florida (7%). The most frequent recipient cities were San Francisco, CA (4 grants), Boston, MA (2 grants), Los Angeles, CA (2 grants) and St. Louis, MO (2 grants).
Does Target ALS Foundation Inc give general operating support?
Not in 2025: none of the 47 grants with a stated purpose on Target ALS Foundation Inc's 2025 IRS Form 990 were described as general or operating support. Recurring purposes include "Scientific Research" (47 grants).
Who are Target ALS Foundation Inc's largest grantees?
Target ALS Foundation Inc's largest 2025 grantees include Dignity Health ($800,313), University of California San Francisco ($731,472) and Mayo Clinic Jacksonville ($579,510), according to its 2025 IRS Form 990. Together they received 21% of its itemized 2025 grant dollars.
How large is Target ALS Foundation Inc?
Target ALS Foundation Inc reported $136.9M in total assets on its 2025 IRS Form 990. Its revenue that year was $33.3M.
What does Target ALS Foundation Inc fund?
The foundation’s mission is to break down barriers to ALS research to find effective treatments by uniting academia, the pharma and biotech industry, government, venture capital, related nonprofits, and the ALS community. See mission & focus areas ↑
How do I apply for a grant from Target ALS Foundation Inc?
The foundation states that it makes contributions only to preselected charitable organizations and does not accept unsolicited requests. Eligibility and process details are in the grantmaking section of this profile. See how to apply ↑
What is Target ALS Foundation Inc's EIN?
Target ALS Foundation Inc's EIN (Employer Identification Number) is 81-0756743. IRS Form 990 filing data is available on this page for 2019–2025.
Does Target ALS Foundation Inc accept unsolicited proposals?
No, according to Grantable's research on the foundation's published guidelines. See how to apply ↑
Data last updated September 2026. Sourced from IRS Form 990 filings. Research dossier generated September 2026.
Data update history
(8)
When this profile's IRS filing data changed on Grantable
- Updated Form 990-PF for fiscal year 2019 (received by the IRS June 3, 2021)
- Updated Form 990-PF for fiscal year 2020 (received by the IRS April 23, 2021)
- Updated Form 990-PF for fiscal year 2021 (received by the IRS May 4, 2022)
- Updated Form 990-PF for fiscal year 2022 (received by the IRS May 5, 2023)
- Updated Form 990-PF for fiscal year 2023 (received by the IRS August 1, 2024)
- Updated Form 990-PF for fiscal year 2024 (received by the IRS May 14, 2025)
- Updated Form 990 for fiscal year 2025 (received by the IRS April 20, 2026)
- IRS filings on file for fiscal years 2019–2025
Explore Open Grants
Browse active grant opportunities in Target ALS Foundation Inc's focus areas in our free grants database
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Cite this profile
Grantable. (2026). Target ALS Foundation Inc funder profile. GrantGraph. Retrieved October 14, 2026, from https://grantable.co/funders/target-als-foundation-inc-morg_a8cc0061aa4e4700bd72e61a7983c8f8
BibTeX
@misc{grantable_810756743_2026,
author = {{Grantable}},
title = {{Target ALS Foundation Inc funder profile}},
howpublished = {GrantGraph},
year = {2026},
url = {https://grantable.co/funders/target-als-foundation-inc-morg_a8cc0061aa4e4700bd72e61a7983c8f8},
note = {Accessed 2026-10-14. Data licensed CC BY 4.0}
}The figures on this page are open data under CC BY 4.0: reuse them with credit to Grantable and a link. Download the data.
Figures come from Target ALS Foundation Inc's IRS filings (methodology). AI-written summaries, news items and logos are not covered by the open licence. Spot an error? Email hello@grantable.co.
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