| Wilhelmina C O'connor Trust Xxxxx5006 | $484,402 | 2 | 2024–2025 |
| Vanguard Charitable Endowment Program | $473,250 | 1 | 2024 |
| The Trustees of Columbia University | $460,144 | 1 | 2024 |
| Families of Spinal Muscular Atrophy | $413,400 | 3 | 2024–2025 |
| The Yvette & Joel Mallah Family Foundation | $400,000 | 2 | 2024 |
| Parkinson's Foundation Inc | $398,592 | 6 | 2024–2025 |
| President and Fellows of Harvard College | $362,499 | 1 | 2024 |
| The Gilbert Family Foundation | $358,678 | 1 | 2024 |
| Cornell University | $352,928 | 1 | 2024 |
| Family Health International Inc | $352,133 | 1 | 2024 |
| Combined Jewish Philanthropies of Greater Boston Inc | $351,500 | 1 | 2024 |
| The David and Lucile Packard Foundation | $350,000 | 2 | 2024 |
| Yale University | $335,107 | 1 | 2024 |
| Ua for Helene Fuld Health Trust 10-205620 | $330,000 | 1 | 2024 |
| The Chicago Community Trust | $291,387 | 1 | 2024 |
| Alzheimer's Disease Research Foundation | $287,500 | 1 | 2024 |
| Research Corporation dba Research | $264,000 | 4 | 2024 |
| Alison Foundation | $250,000 | 1 | 2024 |
| Carnegie Mellon University | $240,823 | 1 | 2024 |
| Edward P Evans Foundation | $237,500 | 1 | 2024 |
| The Leslie and Sheila Klein | $230,000 | 1 | 2024 |
| Prostate Cancer Foundation | $225,000 | 1 | 2024 |
| Fred Hutchinson Cancer Center | $223,383 | 1 | 2024 |
| Emory University | $222,636 | 1 | 2024 |
| The Parent Project for Muscular | $210,000 | 1 | 2024 |
| University of Notre Dame du Lac | $194,180 | 1 | 2024 |
| University of Chicago | $190,070 | 1 | 2024 |
| Univ of Rochester Ua Hwr | $181,662 | 2 | 2024–2025 |
| Fuzehub Inc | $175,680 | 2 | 2024 |
| The Scripps Research Institute | $173,344 | 1 | 2024 |
| Seattle Children's Hospital | $157,867 | 1 | 2024 |
| The George Washington University | $154,180 | 1 | 2024 |
| Co-tr Uart 19 Ow Mae Stone Goode 12-208920 | $150,000 | 2 | 2024–2025 |
| American Academy of Neurology Institute | $150,000 | 1 | 2024 |
| The Hajim Family Foundation | $150,000 | 2 | 2024 |
| James P O'connor Charitable Trust B Xxxxx6003 | $148,084 | 4 | 2024–2025 |
| Frederick F Oconnor Tr Fbo University of | $135,611 | 2 | 2024–2025 |
| Rensselaer Polytechnic Institute | $135,062 | 2 | 2024 |
| Lupus Research Alliance Inc | $134,000 | 1 | 2024 |
| Mayo Clinic | $129,670 | 1 | 2024 |
| University of Miami | $127,174 | 1 | 2024 |
| Arthritis National Research Foundation | $125,000 | 1 | 2025 |
| Health Resources in Action Inc | $125,000 | 1 | 2024 |
| Children's Cancer Research Fund | $125,000 | 1 | 2024 |
| Alexs Lemonade Stand Foundation | $125,000 | 1 | 2024 |
| The Children's Hospital of Philadelphia | $119,526 | 1 | 2024 |
| The Us Charitable Gift Trust | $118,459 | 1 | 2024 |
| National Multiple Sclerosis Society | $116,875 | 1 | 2024 |
| Krfrench Family Foundation | $115,726 | 1 | 2024 |
| Carpenter Family Caritas Foundation | $115,036 | 2 | 2025 |
| Alfred P Sloan Foundation | $105,000 | 2 | 2024 |
| American Academy of Sleep Medicine | $100,000 | 1 | 2024 |
| The Harry T Mangurian Jr | $100,000 | 1 | 2024 |
| Friedreich's Ataxia Research Alliance | $100,000 | 1 | 2024 |
| The Reh Family Foundation | $100,000 | 1 | 2024 |
| Fraser-parker Foundation | $98,985 | 1 | 2024 |
| Coherent Ii-vi Foundation | $95,000 | 1 | 2024 |
| The Child Health Foundation | $90,000 | 2 | 2024 |
| Autism Speaks Inc | $89,714 | 1 | 2024 |
| Dean C Zutes Charitable Trust Xxxxx4007 | $89,530 | 1 | 2024 |
| Richard & Barbara Coleman Charitable Tr | $86,449 | 1 | 2024 |
| John O'connor Tr Fbo Univ of Rochester | $81,844 | 2 | 2024–2025 |
| Chernowitz Medical Research | $80,000 | 1 | 2024 |
| The Singer Family Charitable Foundation | $80,000 | 2 | 2024 |
| J P O'connor Mem Trust Iii Xxxxx7002 | $76,985 | 2 | 2024–2025 |
| The William Penn Foundation | $75,000 | 1 | 2024 |
| Foundation for Chemistry Research | $75,000 | 1 | 2024 |
| Hispanic Scholarship Fund | $73,225 | 2 | 2024–2025 |
| Morgan Stanley Global Impact Funding Trust Inc | $73,000 | 1 | 2024 |
| Association of Universities for Research | $68,295 | 1 | 2024 |
| The Baker Foundation | $67,577 | 1 | 2024 |
| Virginia Insley Charitable Trust | $66,684 | 2 | 2024 |
| Musculoskeletal Transplant | $66,667 | 1 | 2024 |
| The Bond Family Foundation | $60,750 | 1 | 2024 |
| The Fournier Family Charitable Foundation | $55,000 | 1 | 2024 |
| Thomas Jefferson University | $53,148 | 1 | 2024 |
| Arnold and Mabel Beckman Foundation | $52,000 | 2 | 2024 |
| American Cancer Society Inc | $50,000 | 1 | 2024 |
| FRAXA Research Foundation Inc | $50,000 | 1 | 2024 |
| Thomas Dubois Hormel Foundation Inc | $50,000 | 1 | 2024 |
| The Teagle Foundation | $50,000 | 1 | 2024 |
| National Parent Leadership Institute Inc | $50,000 | 1 | 2024 |
| American Hearing Research Foundation | $50,000 | 1 | 2024 |
| American Academy of Sleep Medicine | $50,000 | 1 | 2024 |
| The Spencer Foundation | $49,751 | 1 | 2025 |
| Robert E and Leila Stegner Family Foundation | $49,337 | 1 | 2024 |
| Public Health Institute | $44,000 | 1 | 2024 |
| Donald Insley Charitable Trust | $43,097 | 1 | 2024 |
| Charities Aid Foundation America | $37,975 | 1 | 2024 |
| Joseph & Irene Skalny Char Tr (live) 38370010 | $35,000 | 1 | 2024 |
| The Ayco Charitable Foundation | $34,464 | 1 | 2024 |
| Tr Uw David E Bryant Para 28 D | $33,000 | 1 | 2025 |
| Washington Center for Equitable Growth | $30,000 | 1 | 2024 |
| Beckman Family Foundation | $30,000 | 1 | 2024 |
| The Dillon Fund | $30,000 | 1 | 2024 |
| Nova Southeastern University Inc | $29,139 | 1 | 2024 |
| The Masonic Foundation of the District of Columbia | $27,500 | 2 | 2024–2025 |
| Tw Etta Bascom Fbo Strong Memorial | $26,295 | 1 | 2024 |
| Amyotrophic Lateral Sclerosis Assn | $25,000 | 1 | 2025 |
| Messinger Family Foundation Inc | $25,000 | 1 | 2024 |
| The Ellen and Donald Bilgore | $25,000 | 1 | 2024 |
| Fairfield County's Community Foundation | $25,000 | 1 | 2024 |
| Education Development Center Inc | $24,863 | 1 | 2024 |
| Chapman University | $21,357 | 1 | 2024 |
| Raymond James Charitable Endowment Fund | $20,533 | 1 | 2024 |
| Tr Uw Cecil M Hayesscholarship Fd | $20,179 | 1 | 2024 |
| Fred L Emerson Foundation Inc | $20,000 | 1 | 2024 |
| The Essick Foundation Inc | $20,000 | 1 | 2024 |
| Scoliosis Research Society | $20,000 | 1 | 2024 |
| American Psychological Foundation | $20,000 | 1 | 2024 |
| Bennack Polan Foundation | $20,000 | 1 | 2024 |
| Community Foundation of the Ozarks Inc | $20,000 | 1 | 2024 |
| Abner Perry Hard Fellowship Trust Louise a | $19,157 | 1 | 2024 |
| Sandberg Goldberg Bernthal | $19,130 | 1 | 2024 |
| John D and Seana L Holtz Foundation | $18,000 | 1 | 2024 |
| Raymond Foundation | $18,000 | 1 | 2024 |
| Ronald J York Scholarship Fund | $15,000 | 1 | 2025 |
| Central New York Community Foundation | $14,400 | 1 | 2025 |
| Rochester Area Community Foundation | $7,500 | 1 | 2025 |
| Saccomanno Higher Education Foundation | $7,000 | 1 | 2025 |
| F F O'connor for M Schmidt Xxxxx8009 | $6,058 | 2 | 2025 |
| Ethel M Looram Foundation Inc | $3,500 | 1 | 2025 |
| F F O'connor Charitable Trust B Xxxxx5005 | $3,016 | 1 | 2025 |
| Xu and Yeung Foundation | $2,000 | 1 | 2025 |
| Frank & Ellen Cobb Memorial Scholars Sch9012 | $1,000 | 1 | 2025 |
| Blanchard Arthur F Tr Uagree | $500 | 1 | 2025 |
| The Martin and Nora Salzman Foundation | $250 | 1 | 2025 |