Edward J Mallinckrodt Jr Foundation logo

Edward J Mallinckrodt Jr Foundation

Private foundation · Grantmaker St. Louis, MO EIN: 43-6030295 Website
HealthMedical specialtiesBiomedicineDiseases and conditions

The Edward J Mallinckrodt Jr Foundation is a private foundation based in St. Louis, Missouri. Founded in 1953, it supports early-stage biomedical investigators conducting basic and translational research with the potential to advance biomedical science.

Edward J Mallinckrodt Jr Foundation at a glance

In short: Edward J Mallinckrodt Jr Foundation gave $3.0M across 33 grants in 2025 (avg $91K), top state Missouri. 21% of 2025 grantees were new. Source: 2025 IRS Form 990-PF.

Annual giving (2025)
$3,007,000
+32.6% vs 2024
Grants made (2025)
33
+43.5% vs 2024
Average grant
$91,121
-7.6% vs 2024
Median grant
$75,000
Total assets
$54,707,323
+0.9% vs 2024
New grantees (estimate)
21% first-time grantees (5 of 24, 2025; small sample)
Primary geography
Missouri (31% of itemized 2025 grant dollars)
Latest 990 filing
Form 990-PF, 2025 View filing

Data from IRS Form 990-PF, 2025; updated October 2026. New grantees are estimated by matching recipient names across years (methodology).

How to apply to Edward J Mallinckrodt Jr Foundation

Invitation Only

The foundation’s website describes proposal requirements and limited institutional submissions for the Grant Program, and an invitation-only process for the Scholar Program. Its 2023 filing listed William Polk as the contact for applications and described proposals with a lay-accessible summary, a detailed description, and references.

Review Cycle
The foundation’s announced Grant Program deadline of July 1, 2026, at 5:00 p.m. Central time has passed.
Deadline
The foundation’s announced Grant Program deadline of July 1, 2026, at 5:00 p.m.
Contact

Application contact: Mr William Polk
Mailing address: 7711 Bonhomme Avenue Suite 875, St Louis, MO 63105
Phone: (618) 520-2977
Website: https://emallinckrodtfoundation.org

Application details from Grantable's research on the foundation's public materials; confirm on its website before applying.

Who Edward J Mallinckrodt Jr Foundation funds

How this funder distributes its grants

Top Recipients

Top 10 recipients in 2025

Washington University: $707K across 6 grantsWashington University$707K · 6 grantsHarvard: $300K across 3 grantsHarvard$300K · 3 grantsRegents of the University of California: $150K across 2 grantsRegents of the University ofCalifornia$150K · 2 grantsWashington University School of Medicine: $150K across 2 grantsWashington University Schoolof Medicine$150K · 2 grantsColumbia University: $125KColumbia University$125KMemorial Sloan Cancer Center: $125KMemorial Sloan Cancer Center$125KRockefeller: $125KRockefeller$125KBaylor: $100KBaylor$100KCaltech: $100KCaltech$100KBroad Institute: $75KBroad Institute$75K

The largest 2025 recipient was Washington University ($707K across 6 grants). Together the top 10 received $2.0M.

Organizations only. It also paid 1 grant to individuals ($75,000), which are not listed by name.

Grant Size Distribution

133 grants across all recorded years

9<$50K78$50–100K42$100–250K3$250–500K1$500K–1M$1–5M$5M+

The most common grant size was in the $50–100K range: 78 grants of 133 (59%).

Geographic Focus

Where this funder awards grants

The foundation’s programs are restricted to U.S. institutions. In filing year 2025, Missouri recipients accounted for 31% of grant dollars, followed by California at 16%, Massachusetts at 15%, New York at 15%, and Illinois at 5%.

Grant Distribution by State

17states

Share of 2025 grant dollars across all 33 itemized grants.

Cities

St. LouisNew YorkCambridgePasadenaSan FranciscoLos AngelesTorrancePhiladelphiaAtlantaBerkeleyClevelandNashvilleSeattleWacoBirminghamBoulderDurhamKansas CityLa JollaOklahoma City

Is Edward J Mallinckrodt Jr Foundation open to new grantees?

21%

first-time grantees, 2025

In 2025, 5 of 24 grantees (21%) were first-time recipients. With only 24 grantees, that is a small sample: one grantee more or less moves the share by about 4 points. First grants averaged $75K; repeat grants $139K. How we count

Medians: $75K first-time, $75K repeat.

  • 67% of 2025 grantees were also funded in 2024. Method
  • Giving grew 88% from 2022 to 2025. Method
  • In 2025 it paid out 113% of its IRS minimum distribution (the 5% rule). Method

Estimate from itemized grant lists in IRS Form 990-PF filings (2019–2025). Recipient names are matched across years, so a renamed or misspelled grantee can look new; grants to individuals are left out. Methodology.

Giving History

Giving Over Time

Total grant dollars and number of grants per year

$0$1M$2M$3M$4M27 grants2019 25 grants2020 26 grants2021 24 grants2022 27 grants2023 23 grants2024 33 grants2025

From 2019 to 2025, annual grant giving ranged from $1.6M (2022) to $3.0M (2025). In 2025 it made 33 grants totaling $3.0M.

Grants by year

Grant recipients and amounts by year

RecipientPurposeAmount
Washington University St. Louis, MOFellowship (Fellowship)$332,000
Columbia University New York, NYScholar Program (Dr. Sternberg)$125,000
Harvard Cambridge, MAScholar Program (Dr. Hormoz)$125,000
Memorial Sloan Cancer Center New York, NYScholar Program (Dr. Finley)$125,000
Rockefeller New York, NYScholar Program (Dr. Victoria)$125,000
Washington University St. Louis, MOScholar Program (Dr. Theunissen)$125,000
Baylor Waco, TXScholar Program (Dr. Samuel)$100,000
Caltech Pasadena, CAScholar Program (Dr. Oka)$100,000
Harvard Cambridge, MAScholar Program (Dr. Klein)$100,000
Washington University St. Louis, MOWashington University for PSTP Diversity Initiative$100,000
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Financial History

Multi-year comparison from IRS filings

Figures from IRS filings, by filing year
Filing yearTotal AssetsRevenueExpensesGrants paidGrantsQualifying DistributionsNet Investment IncomeDistributable Amount
2025$54,707,323$5,190,287$3,296,376$3,007,00033$3,091,387$4,891,176$2,724,822
2024$54,228,762$2,387,449$2,578,511$2,267,00023$2,339,205$2,195,503$2,511,365
2023$46,997,406$3,482,487$2,525,467$2,262,00027$2,323,776$3,309,170$2,379,267
2022$45,471,462$1,857,803$1,877,005$1,603,00024$1,663,614$2,076,560$2,576,937
2021$54,992,230$7,689,496$2,735,071$2,473,00026—$5,927,392$2,679,359
2020$46,996,035$2,528,614$2,248,336$2,044,00025—$2,845,864$2,252,561
2019$46,736,219$1,926,739$2,496,809$2,351,00027—$2,210,575$2,276,924

Under IRS private-foundation payout rules, Edward J Mallinckrodt Jr Foundation reported a distributable amount of $2.7M for 2025 — the minimum it must pay out in qualifying distributions.

Research compiled by Grantable AI from public sources. Last updated October 2026.

Mission & Focus Areas

The foundation’s stated mission is to support early-stage biomedical investigators engaged in basic and translational research that has the potential to make fundamental advances in biomedical science. Its website describes the Grant Program as helping early-career faculty develop research toward independent funding, and the Scholar Program as supporting faculty advancing their research toward NIH or other independent funding.

Its 2025 grants included universities, medical and cancer research centers, and biomedical research institutes. For example, the Broad Institute describes its own mission as advancing biomedicine through research into disease and its treatment, while the Stowers Institute for Medical Research describes its mission as contributing to humanity through medical research on the causes, treatment, and prevention of disease.

Grantmaking

In filing year 2025, the foundation reported 33 grants totaling $3,007,000. Grant amounts ranged from $10,000 to $332,000, with a median of $75,000. Among the largest awards were $332,000 to Washington University for a fellowship, $125,000 each to Columbia University, Harvard, Memorial Sloan Cancer Center, Rockefeller, and Washington University for Scholar Program purposes, and $100,000 each to Baylor, Caltech, Harvard, and Washington University for listed program or research purposes.

The Grant Program is for tenure-track faculty in their first through fourth year at U.S. institutions who hold an M.D. and/or Ph.D. Beginning in 2023, it provides $75,000 annually for up to three years and is not renewable. Candidates must not hold a substantial independent research award, such as an NIH R01 or an equivalent award. Each institution may submit one proposal per session. The foundation does not cover overhead costs; proposals require a detailed budget justification and disclosure of available or pending grants. Annual support is contingent on an approved progress report.

The Scholar Program is for tenure-track faculty in their fifth through eighth year who hold an M.D. and/or Ph.D. at U.S. institutions. Beginning in 2024, it provides $125,000 annually for four years. It is by invitation only, with 31 institutions invited to submit two candidates. Proposals require institutional approval letters, a detailed budget justification, and disclosure of available or pending grants; overhead is not covered. Annual support is contingent on an approved progress report.

Leadership & Key People

Leadership team and compensation from IRS filings

The 2025 filing lists William L. Polk Jr. as president; Dr. Alan Schwartz as vice-president; and Rebecca Blankenship as executive director and secretary. Directors listed on that filing are Spencer B. Burke, Dr. Aaron DiAntonio, Dr. Kerry Kornfeld, Dr. Deborah Lenschow, Julie Lilly, and Ted Samuels.

Edward J Mallinckrodt Jr Foundation is led by Rebecca Blankenship, Executive Director & Secretary since 2024 (on filings since 2019); 1 of 9 officers listed in 2025 is compensated.

Officers on the 2025 filing

  • Rebecca Blankenship

    Executive Director & Secretary

    Assistant Secretary → Executive Director & Secretary, 2024

    On filings since 2019

    25 hrs/week

    $50K (2019) → $60K (2025)

  • William L. Polk Jr.

    President

    Vice President → President, 2024

    On filings since 2019

    1 hr/week

    No compensation reported

  • Aaron Diantonio

    Director

    On filings since 2019

    1 hr/week

    No compensation reported

  • Spencer B. Burke

    Director

    President → Director, 2024

    On filings since 2019

    1 hr/week

    No compensation reported

  • Ted Samuels

    Director

    On filings since 2019

    1 hr/week

    No compensation reported

  • Deborah Lenschow

    Director

    On filings since 2022

    1 hr/week

    No compensation reported

  • Julie Lilly

    Director

    On filings since 2022

    1 hr/week

    No compensation reported

  • Kerry Kornfeld

    Director

    On filings since 2024

    1 hr/week

    No compensation reported

  • Alan Schwartz

    Vice President

    Director → Vice President, 2024

    On filings since 2019

    1 hr/week

    No compensation reported

Former officers (4)
  • Former: Lila Solnica-Krezel (2019–2023) — Director
  • Former: Marian V. Mehan (2019–2021) — Secretary
  • Former: Stuart Kornfeld (2019–2021) — Director
  • Former: Tom Cori (2019) — Director

Data from IRS Form 990 filings, 2019–2025. "On filings since" is the earliest filing we hold that lists the person; hours are average hours per week as reported.

Compensation Overview

From 2025 IRS filing

Rebecca Blankenship — Executive Director & Secretary: $60KRebecca BlankenshipExecutive Director & Secretary$60K

The highest reported compensation on the 2025 filing was $60K, to Rebecca Blankenship (Executive Director & Secretary).

Frequently asked questions about Edward J Mallinckrodt Jr Foundation

How much does Edward J Mallinckrodt Jr Foundation give each year?

Edward J Mallinckrodt Jr Foundation gave $3.0M across 33 grants in 2025, according to its 2025 IRS Form 990-PF. In 2024 it gave $2.3M across 23 grants.

What is Edward J Mallinckrodt Jr Foundation's typical grant size?

Edward J Mallinckrodt Jr Foundation's median grant in 2025 was $75,000, and its average grant was $91,121, across 33 grants on its 2025 IRS Form 990-PF. Organizations receiving their first grant from Edward J Mallinckrodt Jr Foundation that year got $75K on average.

Where does Edward J Mallinckrodt Jr Foundation give grants?

Edward J Mallinckrodt Jr Foundation's top state is Missouri, with 31% of the grant dollars itemized on its 2025 IRS Form 990-PF. The next largest states were California (16%) and Massachusetts (15%). The most frequent recipient cities were St. Louis, MO (8 grants), Cambridge, MA (5 grants), New York, NY (3 grants) and Pasadena, CA (2 grants).

Does Edward J Mallinckrodt Jr Foundation give general operating support?

Not in 2025: none of the 33 grants with a stated purpose on Edward J Mallinckrodt Jr Foundation's 2025 IRS Form 990-PF were described as general or operating support.

Who are Edward J Mallinckrodt Jr Foundation's largest grantees?

Edward J Mallinckrodt Jr Foundation's largest 2025 grantees include Washington University ($707,000 across 6 grants), Harvard ($300,000 across 3 grants) and Regents of the University of California ($150,000 across 2 grants), according to its 2025 IRS Form 990-PF. It also paid 1 grant to individuals ($75,000), which are not listed by name. Together they received 38% of its itemized 2025 grant dollars.

How large is Edward J Mallinckrodt Jr Foundation?

Edward J Mallinckrodt Jr Foundation reported $54.7M in total assets on its 2025 IRS Form 990-PF. It paid out $3.1M in qualifying distributions that year, against a required minimum of $2.7M (roughly 5% of its investment assets).

What does Edward J Mallinckrodt Jr Foundation fund?

The foundation’s stated mission is to support early-stage biomedical investigators engaged in basic and translational research that has the potential to make fundamental advances in biomedical science. See mission & focus areas ↑

How do I apply for a grant from Edward J Mallinckrodt Jr Foundation?

The foundation’s website describes proposal requirements and limited institutional submissions for the Grant Program, and an invitation-only process for the Scholar Program. Eligibility and process details are in the grantmaking section of this profile. See how to apply ↑

What is Edward J Mallinckrodt Jr Foundation's EIN?

Edward J Mallinckrodt Jr Foundation's EIN (Employer Identification Number) is 43-6030295. IRS Form 990 filing data is available on this page for 2019–2025.

Data last updated October 2026. Sourced from IRS Form 990-PF filings. Research dossier generated October 2026.

Data update history

(8)

When this profile's IRS filing data changed on Grantable

  1. Updated Form 990-PF for fiscal year 2019 (received by the IRS March 4, 2020)
  2. Updated Form 990-PF for fiscal year 2020 (received by the IRS March 9, 2021)
  3. Updated Form 990-PF for fiscal year 2021 (received by the IRS March 3, 2022)
  4. Updated Form 990-PF for fiscal year 2022 (received by the IRS February 23, 2023)
  5. Updated Form 990-PF for fiscal year 2023 (received by the IRS April 15, 2024)
  6. Updated Form 990-PF for fiscal year 2024 (received by the IRS July 31, 2025)
  7. Updated Form 990-PF for fiscal year 2025 (received by the IRS March 27, 2026)
  8. IRS filings on file for fiscal years 2019–2025

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Cite this profile

Grantable. (2026). Edward J Mallinckrodt Jr Foundation funder profile. GrantGraph. Retrieved October 10, 2026, from https://grantable.co/funders/edward-j-mallinckrodt-jr-foundation-morg_57bc15198a29401c9765a37289d1ed96

BibTeX
@misc{grantable_436030295_2026,
  author       = {{Grantable}},
  title        = {{Edward J Mallinckrodt Jr Foundation funder profile}},
  howpublished = {GrantGraph},
  year         = {2026},
  url          = {https://grantable.co/funders/edward-j-mallinckrodt-jr-foundation-morg_57bc15198a29401c9765a37289d1ed96},
  note         = {Accessed 2026-10-10. Data licensed CC BY 4.0}
}

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Figures come from Edward J Mallinckrodt Jr Foundation's IRS filings (methodology). AI-written summaries, news items and logos are not covered by the open licence. Spot an error? Email hello@grantable.co.

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