The Polg Foundation Inc
The purposes for which the foundation is formed are to address the unmet medical needs of patiens with polg-related disorders with the goal of being able to mitigate or cure such disorders. The foundation intends to (I) identify high-quality scientific research and discoveries in the treatment and diagnosis of polg-related disorders, (II) provide capital to assist in the development of new treatments and diagnostic tools for such disorders; and (III) fund research [and] clinical trials, and invest in mission-related business.
The Polg Foundation Inc at a glance
In short: The Polg Foundation Inc gave $629K across 6 grants in 2025 (avg $105K), mostly in New York. Source: 2025 IRS Form 990.
- Annual giving (2025)
- $628,825
- -5.7% vs 2024
- Grants made (2025)
- 6
- +20.0% vs 2024
- Average grant
- $104,804
- -21.4% vs 2024
- Median grant
- $74,500
- Total assets
- $8,622,383
- +32.1% vs 2024
- Primary geography
- New York (50% of itemized 2025 grant dollars)
- Latest 990 filing
- Form 990, 2025 View filing
Data from IRS Form 990, 2025; updated September 2026.
Who The Polg Foundation Inc funds
How this funder distributes its grants
Top Recipients
Top 6 recipients in 2025
The largest 2025 recipient was Board Institute ($315K). Together the top 6 received $629K.
Grant Size Distribution
14 grants across all recorded years
The most common grant size was under $50K: 7 grants of 14 (50%).
Geographic Focus
Where this funder awards grants
Grant Distribution by State
Share of 2025 grant dollars across all 6 itemized grants.
Cities
Giving History
Giving Over Time
Total grant dollars and number of grants per year
From 2023 to 2025, annual grant giving ranged from $409K (2023) to $667K (2024). In 2025 it made 6 grants totaling $629K.
Grants by year
Grant recipients and amounts by year
| Recipient | Purpose | Amount |
|---|---|---|
| Board Institute New York, NY | Report of post-mortem analysis | $315,000 |
| Across Healthcare LLC Carrollton, GA | Creation of Platform Accross Matrix | $100,000 |
| Jeeva Clinical Trials Inc Manassas, VA | Global Natural History Study | $100,000 |
| University of Miami Coral Gables, FL | An Ex Vivo Human mtDNA Myopathy Mod | $49,000 |
| United Mitochondrial Disease Pittsburgh, PA | Natural history study (Mito) | $39,825 |
| Childrens Hospital of PA Philadelphia, PA | Creation of a POLG Crisis Response | $25,000 |
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Financial History
Multi-year comparison from IRS filings
| Filing year | Total Assets | Revenue | Expenses | Grants paid | Grants | Net Investment Income |
|---|---|---|---|---|---|---|
| 2025 | $8,622,383 | $3,364,753 | $2,107,901 | $628,825 | 6 | $254,740 |
| 2024 | $6,529,501 | $1,297,847 | $2,097,172 | $666,524 | 5 | $346,149 |
| 2023 | $7,528,235 | $983,511 | $2,087,691 | $408,750 | 3 | $313,007 |
| 2022 | $8,139,856 | $7,954,948 | $791,460 | — | — | — |
| 2021 | $797,470 | $840,696 | $43,226 | — | — | — |
About The Polg Foundation Inc
Based on IRS filings
The Polg Foundation Inc is a public charity focused on Diseases, Disorders & Medical Disciplines, based in New York, NY. IRS filing data is available from 2021 through 2025. As of 2025, the organization holds $8.6M in total assets. In 2025, it awarded 6 grants totaling $629K. Net investment income was $255K.
Focus Areas
Leadership & Key People
Officers and directors from IRS filings
The Polg Foundation Inc is led by Robert De Luxembourg, Chairman since 2024 (on filings since 2021); 1 of 12 officers listed in 2025 is compensated.
Officers on the 2025 filing
Robert De Luxembourg
Chairman
Chairman → Chair, 2022
Chair → Chairman, 2024
On filings since 2021
1 hr/week
No compensation reported
Brian Tseng
Director & Cso
Director & Chief Science Officer → Director, 2024
Director → Director & Cso, 2025
On filings since 2022
40 hrs/week
$207K (2023) → $316K (2025)
Cindy Gavin
Director
Director → Director & Secretary, 2023
Director & Secretary → Director, 2024
On filings since 2022
1 hr/week
$30K (2022) → $0 (2025)
Allyson Ocean
Director
On filings since 2021
1 hr/week
No compensation reported
Jennifer Adams
Director
On filings since 2021
1 hr/week
No compensation reported
Jrg Duschmale
Director
On filings since 2021
1 hr/week
No compensation reported
Stven Altschuler
Director
On filings since 2021
1 hr/week
No compensation reported
Francesco De Rubertis
Director
On filings since 2022
1 hr/week
No compensation reported
Remy Best
Director
On filings since 2022
1 hr/week
No compensation reported
Eileen Kane
Corp. Secretary
Corporate Sectretary → Corporate Secretary, 2023
Corporate Secretary → Corp. Secretary, 2024
On filings since 2021
1 hr/week
No compensation reported
Julie De Luxembourg
Vice Chair
On filings since 2021
1 hr/week
No compensation reported
Marcus Siezing
Treasurer
On filings since 2021
1 hr/week
No compensation reported
Former officers (2)
- Former: Samuel Seward (2024) — Executive Director
- Former: Olivier Gerrits (2022) — Executive Director
Data from IRS Form 990 filings, 2021–2025. "On filings since" is the earliest filing we hold that lists the person; hours are average hours per week as reported.
Compensation Overview
From 2025 IRS filing
The highest reported compensation on the 2025 filing was $316K, to Brian Tseng (Director / CSO).
Frequently asked questions about The Polg Foundation Inc
How much does The Polg Foundation Inc give each year?
The Polg Foundation Inc gave $629K across 6 grants in 2025, according to its 2025 IRS Form 990. In 2024 it gave $667K across 5 grants.
What is The Polg Foundation Inc's typical grant size?
The Polg Foundation Inc's median grant in 2025 was $74,500, and its average grant was $104,804, across 6 grants on its 2025 IRS Form 990.
Where does The Polg Foundation Inc give grants?
The Polg Foundation Inc gives mostly in New York: 50% of the grant dollars itemized on its 2025 IRS Form 990 went to recipients there. The next largest states were Georgia (16%) and Virginia (16%).
Does The Polg Foundation Inc give general operating support?
Not in 2025: none of the 6 grants with a stated purpose on The Polg Foundation Inc's 2025 IRS Form 990 were described as general or operating support.
Who are The Polg Foundation Inc's largest grantees?
The Polg Foundation Inc's largest 2025 grantees include Board Institute ($315,000), Across Healthcare LLC ($100,000) and Jeeva Clinical Trials Inc ($100,000), according to its 2025 IRS Form 990. Together they received 82% of its itemized 2025 grant dollars.
How large is The Polg Foundation Inc?
The Polg Foundation Inc reported $8.6M in total assets on its 2025 IRS Form 990. Its revenue that year was $3.4M.
What is The Polg Foundation Inc?
The Polg Foundation Inc is a public charity focused on Diseases, Disorders & Medical Disciplines, based in New York, NY. It holds $8.6M in total assets as of 2025.
What is The Polg Foundation Inc's EIN?
The Polg Foundation Inc's EIN (Employer Identification Number) is 87-1876876. IRS Form 990 filing data is available on this page for 2021–2025.
Data last updated September 2026. Sourced from IRS Form 990 filings.
Data update history
(3)
When this profile's IRS filing data changed on Grantable
- Updated Form 990 for fiscal year 2023 (received by the IRS November 14, 2024)
- Updated Form 990 for fiscal year 2024 (received by the IRS May 15, 2025)
- Added Form 990 for fiscal year 2025 (received by the IRS May 15, 2026)
Live grants for the work The Polg Foundation Inc funds
Diseases, Disorders & Medical Disciplines Open opportunities, soonest deadline first.
Explore Open Grants
Browse active grant opportunities in The Polg Foundation Inc's focus areas in our free grants database
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