The Polg Foundation Inc logo

The Polg Foundation Inc

Public charity · Grantmaker New York, NY EIN: 87-1876876 Website

The purposes for which the foundation is formed are to address the unmet medical needs of patiens with polg-related disorders with the goal of being able to mitigate or cure such disorders. The foundation intends to (I) identify high-quality scientific research and discoveries in the treatment and diagnosis of polg-related disorders, (II) provide capital to assist in the development of new treatments and diagnostic tools for such disorders; and (III) fund research [and] clinical trials, and invest in mission-related business.

Key facts about The Polg Foundation Inc

In short: The Polg Foundation Inc gave $629K across 6 grants in 2025 (avg $105K), mostly in New York. Source: 2025 IRS Form 990.

EIN
87-1876876
Latest 990 filing
Form 990, 2025
Annual giving (2025)
$628,825
Grants made (2025)
6
Average grant
$104,804
Median grant
$74,500
Total assets
$8,622,383
Primary geography
New York (50% of itemized 2025 grant dollars)

Data from IRS Form 990, 2025; updated September 2026.

Financial Overview

From 2025 IRS Form 990 · View filing

Total Assets

$8.6M

+32.1% YoY

Annual Giving

$629K

-5.7% YoY

Grant Count

6

+20.0% YoY

Avg Grant Size

$105K

-21.4% YoY

About The Polg Foundation Inc

Based on IRS filings

The Polg Foundation Inc is a public charity focused on Diseases, Disorders & Medical Disciplines, based in New York, NY. IRS filing data is available from 2021 through 2025. As of 2025, the organization holds $8.6M in total assets. In 2025, it awarded 6 grants totaling $629K. Net investment income was $255K.

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Geographic Focus

Where this funder awards grants

Grant Distribution by State

7states

Share of 2025 grant dollars across all 6 itemized grants.

Cities

CambridgePhiladelphiaNew YorkPittsburghBar HarborCarrolltonCoral GablesManassas

Giving Over Time

Total grant dollars and number of grants per year

$0$200K$400K$600K$800K0 grants2021 0 grants2022 3 grants2023 5 grants2024 6 grants2025

From 2023 to 2025, annual grant giving ranged from $409K (2023) to $667K (2024). In 2025 it made 6 grants totaling $629K.

Grant Insights

How this funder distributes its grants

Top Recipients

Top 6 recipients in 2025

Board Institute: $315KBoard Institute$315KAcross Healthcare LLC: $100KAcross Healthcare LLC$100KJeeva Clinical Trials Inc: $100KJeeva Clinical Trials Inc$100KUniversity of Miami: $49KUniversity of Miami$49KUnited Mitochondrial Disease: $40KUnited Mitochondrial Disease$40KChildrens Hospital of PA: $25KChildrens Hospital of PA$25K

The largest 2025 recipient was Board Institute ($315K). Together the top 6 received $629K.

Grant Size Distribution

14 grants across all recorded years

7<$50K1$50–100K2$100–250K4$250–500K$500K–1M$1–5M$5M+

The most common grant size was under $50K: 7 grants of 14 (50%).

Giving History

Grant recipients and amounts by year

RecipientPurposeAmount
Board Institute New York, NYReport of post-mortem analysis$315,000
Across Healthcare LLC Carrollton, GACreation of Platform Accross Matrix$100,000
Jeeva Clinical Trials Inc Manassas, VAGlobal Natural History Study$100,000
University of Miami Coral Gables, FLAn Ex Vivo Human mtDNA Myopathy Mod$49,000
United Mitochondrial Disease Pittsburgh, PANatural history study (Mito)$39,825
Childrens Hospital of PA Philadelphia, PACreation of a POLG Crisis Response$25,000

Financial History

Multi-year comparison from IRS filings

Revenue
Expenses
Net Investment Income
$0$2.5M$5M$7.5M$10M2021 2022 2023 2024 2025
Metric202520242023
Total Assets$8,622,383$6,529,501$7,528,235
Revenue$3,364,753$1,297,847$983,511
Expenses$2,107,901$2,097,172$2,087,691
Net Investment Income$254,740$346,149$313,007

Data update history

When this profile's IRS filing data changed on Grantable

  1. Updated Form 990 for fiscal year 2023 (received by the IRS November 14, 2024)
  2. Updated Form 990 for fiscal year 2024 (received by the IRS May 15, 2025)
  3. Added Form 990 for fiscal year 2025 (received by the IRS May 15, 2026)

Leadership & Key People

Officers and directors from IRS filings

The Polg Foundation Inc is led by Robert De Luxembourg, Chairman since 2024 (on filings since 2021); 1 of 12 officers listed in 2025 is compensated.

Officers on the 2025 filing

  • Robert De Luxembourg

    Chairman

    Chairman → Chair, 2022

    Chair → Chairman, 2024

    On filings since 2021

    1 hr/week

    No compensation reported

  • Brian Tseng

    Director & Cso

    Director & Chief Science Officer → Director, 2024

    Director → Director & Cso, 2025

    On filings since 2022

    40 hrs/week

    $207K (2023) → $316K (2025)

  • Cindy Gavin

    Director

    Director → Director & Secretary, 2023

    Director & Secretary → Director, 2024

    On filings since 2022

    1 hr/week

    $30K (2022) → $0 (2025)

  • Allyson Ocean

    Director

    On filings since 2021

    1 hr/week

    No compensation reported

  • Jennifer Adams

    Director

    On filings since 2021

    1 hr/week

    No compensation reported

  • Jrg Duschmale

    Director

    On filings since 2021

    1 hr/week

    No compensation reported

  • Stven Altschuler

    Director

    On filings since 2021

    1 hr/week

    No compensation reported

  • Francesco De Rubertis

    Director

    On filings since 2022

    1 hr/week

    No compensation reported

  • Remy Best

    Director

    On filings since 2022

    1 hr/week

    No compensation reported

  • Eileen Kane

    Corp. Secretary

    Corporate Sectretary → Corporate Secretary, 2023

    Corporate Secretary → Corp. Secretary, 2024

    On filings since 2021

    1 hr/week

    No compensation reported

  • Julie De Luxembourg

    Vice Chair

    On filings since 2021

    1 hr/week

    No compensation reported

  • Marcus Siezing

    Treasurer

    On filings since 2021

    1 hr/week

    No compensation reported

Former officers (2)
  • Former: Samuel Seward (2024) — Executive Director
  • Former: Olivier Gerrits (2022) — Executive Director

Data from IRS Form 990 filings, 2021–2025. "On filings since" is the earliest filing we hold that lists the person; hours are average hours per week as reported.

Compensation Overview

From 2025 IRS filing

Brian Tseng — Director / CSO: $316KBrian TsengDirector / CSO$316K

The highest reported compensation on the 2025 filing was $316K, to Brian Tseng (Director / CSO).

Frequently asked questions about The Polg Foundation Inc

How much does The Polg Foundation Inc give each year?

The Polg Foundation Inc gave $629K across 6 grants in 2025, according to its 2025 IRS Form 990. In 2024 it gave $667K across 5 grants.

What is The Polg Foundation Inc's typical grant size?

The Polg Foundation Inc's median grant in 2025 was $74,500, and its average grant was $104,804, across 6 grants on its 2025 IRS Form 990.

Where does The Polg Foundation Inc give grants?

The Polg Foundation Inc gives mostly in New York: 50% of the grant dollars itemized on its 2025 IRS Form 990 went to recipients there. The next largest states were Georgia (16%) and Virginia (16%).

Does The Polg Foundation Inc give general operating support?

Not in 2025: none of the 6 grants with a stated purpose on The Polg Foundation Inc's 2025 IRS Form 990 were described as general or operating support.

Who are The Polg Foundation Inc's largest grantees?

The Polg Foundation Inc's largest 2025 grantees include Board Institute ($315,000), Across Healthcare LLC ($100,000) and Jeeva Clinical Trials Inc ($100,000), according to its 2025 IRS Form 990. Together they received 82% of its itemized 2025 grant dollars.

How large is The Polg Foundation Inc?

The Polg Foundation Inc reported $8.6M in total assets on its 2025 IRS Form 990. Its revenue that year was $3.4M.

What is The Polg Foundation Inc?

The Polg Foundation Inc is a public charity focused on Diseases, Disorders & Medical Disciplines, based in New York, NY. It holds $8.6M in total assets as of 2025.

What is The Polg Foundation Inc's EIN?

The Polg Foundation Inc's EIN (Employer Identification Number) is 87-1876876. IRS Form 990 filing data is available on this page for 2021–2025.

Data last updated September 2026. Sourced from IRS Form 990 filings.

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