Manning Family Foundation

CHARLOTTESVILLE, VA EIN: 74-3054138 Website

The Manning Family Foundation is a private foundation established in 2002 in Virginia and tax-exempt since October 2003. Based in Charlottesville, Virginia, the foundation advances health and healthy communities through strategic grantmaking to 501(c)(3) nonprofit organizations. Over its first twenty years, the foundation awarded more than 300 grants to 110 organizations.

Financial Overview

From 2024 IRS Form 990-PF · View filing

Total Assets

$302.4M

+10.0% YoY

Annual Giving

$13.5M

+0.6% YoY

Grant Count

-4.4% YoY

Avg Grant Size

$208K

+5.3% YoY

Under IRS private-foundation payout rules, Manning Family Foundation reported a distributable amount of $14.7M for 2024 — the minimum it must pay out in qualifying distributions.

Research compiled by Grantable AI from public sources. Last updated April 2026.

Mission & Focus Areas

The foundation operates with two primary philanthropic focus areas:

Health & Life Sciences Research: The foundation supports research that leads to the development of more effective treatments and cures for the world's most disruptive diseases. The Mannings have focused particularly on supporting research to treat and cure both type 1 and type 2 diabetes.

Local Giving: The foundation supports groups in Charlottesville, Virginia that share its vision of a thriving community, one in which culture can flourish and families prosper.

Grantmaking

Grant Range

approximately $197,584–$198,000

Average Grant

approximately $197,584–$198,000

How to Apply

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Geographic Focus

Where this funder awards grants

The foundation supports health research grants nationally throughout the United States. Local grants are restricted to Charlottesville, Virginia. The foundation's funding extends across multiple states including California, New York, Virginia, and others.

Grant Distribution by State

Virginia $24.7M (51%)

Maryland $10.1M (21%)

Ohio $4.8M (10%)

Massachusetts $4.0M (8%)

New York $3.2M (7%)

North Carolina $1.5M (3%)

New Jersey $50K (0%)

California $10K (0%)

+6 more states

States

California Connecticut Florida Georgia Illinois Massachusetts Maryland North Carolina New Hampshire New Jersey New York Ohio Pennsylvania Virginia

Cities

AmherstAtlantaBostonBrandonBrookefieldCharlottesvilleCincinnatiClevelandCoatesvilleColumbiaDurhamGoochlandGordonsvilleHancockHanoverHarrionburgHarwichHenricoHinghamKeswick

Financial History

Multi-year comparison from IRS filings

Assets: $275–$302 million (as of 2023–2024)

Annual Giving: $13.4–$13.6 million

Revenue: $8–$8.4 million (2023–2024)

Expenses: $14.3–$14.6 million (2023–2024)

Total Liabilities: $1,180 (2023)

Revenue

Expenses

Qualifying Distributions

Net Investment Income

Metric	2024	2023	2022
Total Assets	$302,402,755	$274,981,200	$253,756,007
Revenue	$8,375,762	$7,998,437	$5,624,625
Expenses	$14,263,739	$14,634,604	$15,909,141
Qualifying Distributions	$13,685,547	$13,551,987	$14,737,810
Net Investment Income	$8,276,722	$6,715,296	$4,453,294
Distributable Amount	$14,668,882	$13,658,293	$13,482,434

Giving Over Time

Total grant dollars and number of grants per year

Grant Insights

How this funder distributes its grants

Top Recipients

Top 10 recipients in 2024

Grant Size Distribution

229 grants across all recorded years

Open Grants

2 open opportunities from Manning Family Foundation

Foundation

Manning Family Health and Life Sciences Research Grants

MANNING FAMILY FOUNDATION

Amount

Varies

Deadline

Rolling / Open

Foundation

Manning Family Local Grants

MANNING FAMILY FOUNDATION

Amount

Varies

Deadline

Rolling / Open

Giving History

Grant recipients and amounts by year

Among its reported 2024 grants, the largest include Fidelity Charitable ($4,800,000), Breakthrough T1d ($1,500,000), Duke University ($304,000).

Recipient	Purpose	Amount
100 BLACK MEN OF CENTRAL VIRGINIA CHARLOTTESVILLE, VA	GENERAL	$30,000
AFFORDABLE HOUSING OPPORTUNITY FUND CHARLOTTESVILLE, VA	GENERAL	$300,000
AKA GEORGIA'S HEALING HOUSE CHARLOTTESVILLE, VA	GENERAL	$20,000
ALBEMARLE COUNTY POLICE FOUNDATION CHARLOTTESVILLE, VA	GENERAL	$102,200
ALBEMARLE YOUTH FOOTBALL PALMYRA, VA	GENERAL	$5,000
ALL BLESSINGS FLOW INC CHARLOTTESVILLE, VA	GENERAL	$25,000
ASSOCIATION FOR RETARDED CITIZENS OF CHARLOTTESVIL CHARLOTTESVILLE, VA	GENERAL	$15,000
BIG BROTHERS BIG SISTERS OF EASTERN MASSACHUSETTS BOSTON, MA	GENERAL	$200,000
BIG BROTHERS BIG SISTERS OF THE CENTRAL BLUE RIDGE CHARLOTTESVILLE, VA	GENERAL	$25,000
BLUE RIDGE AREA FOOD BANK CHARLOTTESVILLE, VA	GENERAL	$75,000

Leadership & Key People

Leadership team and compensation from IRS filings

Paul Manning: Founder and President; founder and CEO of PBM Capital, previously founded PBM Products, which became the world's largest private label producer of infant formula

Diane Manning: Co-founder

Heidi Burnette: Grant Director (as of 2023)

The foundation is led by Paul B. Manning, who serves as Director, President, and Treasurer. None of the directors or officers receive compensation for their roles.

Compensation Overview

From 2024 IRS filing

From 2024 filing

Name	Title	Hours	Compensation
PAUL B MANNING	DIRECTOR, PRESIDENT, TREASURER	1	—
DIANE L MANNING	DIRECTOR AND SECRETARY	1	—
BRADFORD J MANNING	DIRECTOR	1	—
BRYAN P MANNING	DIRECTOR	1	—
KAITLYN M HENRY	DIRECTOR	1	—
RUSSELL T SCHUNDLER	SECRETARY	1	—

Recent News & Activity

Recent developments and announcements

2023

In 2023, Paul and Diane Manning made a transformational $100 million gift to the University of Virginia to establish the Paul and Diane Manning Institute of Biotechnology, projected to open in 2026. This gift made headlines as a significant commitment to advancing biotechnology research and innovation.

Refresh Manning Trust awards $8,000 in 2025 grants | News | carrollspaper.com

2024

Recent grant recipients include the University of Virginia Health Foundation ($3,060,000 in 2024), Breakthrough T1D/JDRF ($1,500,000 in 2024), and The Affordable Housing Opportunity Fund ($300,000 in 2024).

Manning Family Foundation - Grant Information & Application Details

Subject Areas

Focus areas based on grantmaking activity

Philanthropy, Voluntarism & Grantmaking

Frequently Asked Questions

What does Manning Family Foundation fund?

The foundation supports health research and innovation that leads to the development of more effective treatments and ultimately cures for the world's most disruptive diseases. The foundation encourages a spirit of entrepreneurialism to achieve this goal. The foundation operates with two primary philanthropic focus areas: **Health & Life Sciences Research:** The foundation supports research that leads to the development of more effective treatments and cures for the world's most disruptive dise…

How do I apply for a grant from Manning Family Foundation?

**Grant Amounts & Activity:** • Average grant size: approximately $197,584–$198,000 • Grant range: $50,000–$500,000 • Annual giving: $13.4–$13.6 million • 2023: 68 grants totaling $13,435,740 • 2024: 24 grants totaling $240,000 (with additional grants totaling $6,874,523 across 48 total grants) **Application Process:** • Applications are accepted on a rolling basis through the foundation's online web portal • First-time applicants and grantees who have not received funding in over two years mus…

Where does Manning Family Foundation make grants?

What size grants does Manning Family Foundation award?

In 2024, Manning Family Foundation awarded 65 grants totaling $13.5M — an average of about $208K per grant, based on its IRS Form 990 filings.

How much is Manning Family Foundation required to give away each year?

Private foundations must generally distribute about 5% of their assets annually. For 2024, Manning Family Foundation reported a distributable amount of $14.7M on its IRS Form 990-PF — the minimum it must pay out in qualifying distributions.