Manning Family Foundation
The Manning Family Foundation is a private foundation established in 2002 in Virginia and tax-exempt since October 2003. Based in Charlottesville, Virginia, the foundation advances health and healthy communities through strategic grantmaking to 501(c)(3) nonprofit organizations. Over its first twenty years, the foundation awarded more than 300 grants to 110 organizations.
Financial Overview
From 2024 IRS Form 990-PF · View filing
Total Assets
$302.4M
+10.0% YoY
Annual Giving
$13.5M
+0.6% YoY
Grant Count
65
-4.4% YoY
Avg Grant Size
$208K
+5.3% YoY
Under IRS private-foundation payout rules, Manning Family Foundation reported a distributable amount of $14.7M for 2024 — the minimum it must pay out in qualifying distributions.
Mission & Focus Areas
The foundation supports health research and innovation that leads to the development of more effective treatments and ultimately cures for the world's most disruptive diseases. The foundation encourages a spirit of entrepreneurialism to achieve this goal.
The foundation operates with two primary philanthropic focus areas:
Health & Life Sciences Research: The foundation supports research that leads to the development of more effective treatments and cures for the world's most disruptive diseases. The Mannings have focused particularly on supporting research to treat and cure both type 1 and type 2 diabetes.
Local Giving: The foundation supports groups in Charlottesville, Virginia that share its vision of a thriving community, one in which culture can flourish and families prosper.
Grantmaking
Grant Range
approximately $197,584–$198,000
Average Grant
approximately $197,584–$198,000
How to Apply
**
Ready to take the next step with Manning Family Foundation?
Geographic Focus
Where this funder awards grants
The foundation supports health research grants nationally throughout the United States. Local grants are restricted to Charlottesville, Virginia. The foundation's funding extends across multiple states including California, New York, Virginia, and others.
Grant Distribution by State
States
Cities
Financial History
Multi-year comparison from IRS filings
Assets: $275–$302 million (as of 2023–2024)
Annual Giving: $13.4–$13.6 million
Revenue: $8–$8.4 million (2023–2024)
Expenses: $14.3–$14.6 million (2023–2024)
Total Liabilities: $1,180 (2023)
| Metric | 2024 | 2023 | 2022 |
|---|---|---|---|
| Total Assets | $302,402,755 | $274,981,200 | $253,756,007 |
| Revenue | $8,375,762 | $7,998,437 | $5,624,625 |
| Expenses | $14,263,739 | $14,634,604 | $15,909,141 |
| Qualifying Distributions | $13,685,547 | $13,551,987 | $14,737,810 |
| Net Investment Income | $8,276,722 | $6,715,296 | $4,453,294 |
| Distributable Amount | $14,668,882 | $13,658,293 | $13,482,434 |
Giving Over Time
Total grant dollars and number of grants per year
Grant Insights
How this funder distributes its grants
Top Recipients
Top 10 recipients in 2024
Grant Size Distribution
229 grants across all recorded years
Open Grants
2 open opportunities from Manning Family Foundation
Giving History
Grant recipients and amounts by year
Among its reported 2024 grants, the largest include Fidelity Charitable ($4,800,000), Breakthrough T1d ($1,500,000), Duke University ($304,000).
No grants recorded for .
Leadership & Key People
Leadership team and compensation from IRS filings
Paul Manning: Founder and President; founder and CEO of PBM Capital, previously founded PBM Products, which became the world's largest private label producer of infant formula
Diane Manning: Co-founder
Heidi Burnette: Grant Director (as of 2023)
The foundation is led by Paul B. Manning, who serves as Director, President, and Treasurer. None of the directors or officers receive compensation for their roles.
Compensation Overview
From 2024 IRS filing
From 2024 filing
| Name | Title | Hours | Compensation |
|---|---|---|---|
| PAUL B MANNING | DIRECTOR, PRESIDENT, TREASURER | 1 | — |
| DIANE L MANNING | DIRECTOR AND SECRETARY | 1 | — |
| BRADFORD J MANNING | DIRECTOR | 1 | — |
| BRYAN P MANNING | DIRECTOR | 1 | — |
| KAITLYN M HENRY | DIRECTOR | 1 | — |
| RUSSELL T SCHUNDLER | SECRETARY | 1 | — |
Recent News & Activity
Recent developments and announcements
In 2023, Paul and Diane Manning made a transformational $100 million gift to the University of Virginia to establish the Paul and Diane Manning Institute of Biotechnology, projected to open in 2026. This gift made headlines as a significant commitment to advancing biotechnology research and innovation.
Refresh Manning Trust awards $8,000 in 2025 grants | News | carrollspaper.comRecent grant recipients include the University of Virginia Health Foundation ($3,060,000 in 2024), Breakthrough T1D/JDRF ($1,500,000 in 2024), and The Affordable Housing Opportunity Fund ($300,000 in 2024).
Manning Family Foundation - Grant Information & Application DetailsSubject Areas
Focus areas based on grantmaking activity
Frequently Asked Questions
What does Manning Family Foundation fund?
The foundation supports health research and innovation that leads to the development of more effective treatments and ultimately cures for the world's most disruptive diseases. The foundation encourages a spirit of entrepreneurialism to achieve this goal. The foundation operates with two primary philanthropic focus areas: **Health & Life Sciences Research:** The foundation supports research that leads to the development of more effective treatments and cures for the world's most disruptive dise…
How do I apply for a grant from Manning Family Foundation?
**Grant Amounts & Activity:** • Average grant size: approximately $197,584–$198,000 • Grant range: $50,000–$500,000 • Annual giving: $13.4–$13.6 million • 2023: 68 grants totaling $13,435,740 • 2024: 24 grants totaling $240,000 (with additional grants totaling $6,874,523 across 48 total grants) **Application Process:** • Applications are accepted on a rolling basis through the foundation's online web portal • First-time applicants and grantees who have not received funding in over two years mus…
Where does Manning Family Foundation make grants?
The foundation supports health research grants nationally throughout the United States. Local grants are restricted to Charlottesville, Virginia. The foundation's funding extends across multiple states including California, New York, Virginia, and others.
What size grants does Manning Family Foundation award?
In 2024, Manning Family Foundation awarded 65 grants totaling $13.5M — an average of about $208K per grant, based on its IRS Form 990 filings.
How much is Manning Family Foundation required to give away each year?
Private foundations must generally distribute about 5% of their assets annually. For 2024, Manning Family Foundation reported a distributable amount of $14.7M on its IRS Form 990-PF — the minimum it must pay out in qualifying distributions.
What is Manning Family Foundation's EIN?
Manning Family Foundation's EIN (Employer Identification Number) is 74-3054138. IRS Form 990 filing data is available on this page for 2020–2024.
Explore Open Grants
Browse active grant opportunities in Manning Family Foundation's focus areas in our free grants database
Related Funders
Similar funders by location and focus area
Wolf Family Charitable Trust
OAKTON, VA
Assets
$385K
Grants
5
Total Given
$189K
Stone Ridge Foundation
ALTAVISTA, VA
Assets
$6.4M
Grants
2
Total Given
$15K
Lawrence and Ira Straus Charitable Tr
ARLINGTON, VA
Assets
$236K
Grants
12
Total Given
$8K
Iraqi Children Foundation Inc
FAIRFAX, VA
Assets
$101K
Grants
2
Total Given
$610K
Heartfelt Humans
ASHBURN, VA
Assets
—
Grants
0
Total Given
—
Krumbein Charities Inc
RICHMOND, VA
Assets
$440K
Grants
14
Total Given
$34K
Data last updated April 2026. Sourced from IRS Form 990-PF filings. Research dossier generated April 2026.
What could you do with Manning Family Foundation on Grantable?
- Assess strategic fit with your organization
- Draft a tailored letter of inquiry
- Find open RFPs from this funder
- Monitor for new funding opportunities
Go from researching Manning Family Foundation to a real strategy.