Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc logo

Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc

Public charity · Grantmaker Boston, MA EIN: 30-0773387 Website

The Wyss Institute for Biologically Inspired Engineering at Harvard University is a public charity based in Boston, Massachusetts. It develops bioinspired technologies and conducts research and technology development addressing challenges in health care and the environment. The institute collaborates across Harvard and with academic, clinical, and industry partners, and translates discoveries toward real-world use through collaborations, startups, and industry partnerships.

Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc at a glance

In short: Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc gave $9.2M across 12 grants in 2025 (avg $771K), mostly in Massachusetts. 8% of 2025 grantees were new. Source: 2025 IRS Form 990.

Annual giving (2025)
$9,249,939
+26.1% vs 2024
Grants made (2025)
12
-7.7% vs 2024
Average grant
$770,828
+36.6% vs 2024
Median grant
$954,907
Total assets
$478,867,652
-6.6% vs 2024
New grantees (estimate)
8% first-time grantees (1 of 12, 2025; small sample)
Primary geography
Massachusetts (95% of itemized 2025 grant dollars)
Latest 990 filing
Form 990, 2025 View filing

Data from IRS Form 990, 2025; updated October 2026. New grantees are estimated by matching recipient names across years (methodology).

How to apply to Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc

Contact

Mailing address: 201 Brookline Ave Suite 401, Boston, MA 02215
Phone: (617) 432-7061
Website: https://wyss.harvard.edu

Application details from Grantable's research on the foundation's public materials; confirm on its website before applying.

Who Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc funds

How this funder distributes its grants

Top Recipients

Top 10 recipients in 2025

Attivare Therapeutics Inc: $1.7MAttivare Therapeutics Inc$1.7MMassachusetts Institute of Technology: $1.4MMassachusetts Institute ofTechnology$1.4MChildren's Hospital Corporation: $1.2MChildren's HospitalCorporation$1.2MDana-Farber Cancer Institute Inc: $1.1MDana-Farber Cancer InstituteInc$1.1MThe Massachusetts General Hospital: $1.1MThe Massachusetts GeneralHospital$1.1MEnplusone Biosciences Inc: $1.1MEnplusone Biosciences Inc$1.1MThe Brigham and Women's Hospital Inc: $859KThe Brigham and Women'sHospital Inc$859KIcahn School of Medicine at Mount Sinai: $260KIcahn School of Medicine atMount Sinai$260KBeth Israel Deaconess Medical Center: $196KBeth Israel Deaconess MedicalCenter$196KTrustees of Boston University: $193KTrustees of Boston University$193K

The largest 2025 recipient was Attivare Therapeutics Inc ($1.7M). Together the top 10 received $9.0M.

Grant Size Distribution

73 grants across all recorded years

14<$50K6$50–100K12$100–250K13$250–500K14$500K–1M14$1–5M$5M+

The most common grant size was under $50K: 14 grants of 73 (19%).

Geographic Focus

Where this funder awards grants

The 2025 grant dollars went primarily to Massachusetts recipients: 95% went to Massachusetts, 3% to New York, and 2% to California. The institute’s website describes collaborations with academic and clinical institutions in the Boston area and around the world.

Grant Distribution by State

13states

Share of 2025 grant dollars across all 12 itemized grants.

Cities

BostonCambridgeNew YorkSomervillePhiladelphiaRockvilleBrightonHuntsvilleOaklandPrincetonSan AntonioAlbanyBaltimoreBosotnChicagoNatickPittsburghShrewsburyAnn ArborCold Spring Harbor

Is Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc open to new grantees?

8%

first-time grantees, 2025

In 2025, 1 of 12 grantees (8%) were first-time recipients. With only 12 grantees, that is a small sample: one grantee more or less moves the share by about 8 points. First grants averaged $1.1M; repeat grants $745K. How we count

Medians: $1.1M first-time, $859K repeat.

  • 92% of 2025 grantees were also funded in 2024. Method
  • Giving grew 63% from 2022 to 2025. Method

Estimate from itemized grant lists in IRS Form 990 filings (2019–2025). Recipient names are matched across years, so a renamed or misspelled grantee can look new; grants to individuals are left out. Methodology.

Giving History

Giving Over Time

Total grant dollars and number of grants per year

$0$5M$10M$15M23 grants2019 20 grants2020 16 grants2021 17 grants2022 15 grants2023 13 grants2024 12 grants2025

From 2019 to 2025, annual grant giving ranged from $5.1M (2020) to $12.4M (2021). In 2025 it made 12 grants totaling $9.2M.

Grants by year

Grant recipients and amounts by year

RecipientPurposeAmount
Attivare Therapeutics Inc Natick, MANonfed Sponsored$1,693,161
Massachusetts Institute of Technology Cambridge, MAFed/Nonfed Awards$1,375,366
Children's Hospital Corporation Boston, MAFed/Nonfed Sponsored$1,173,360
Dana-Farber Cancer Institute Inc Boston, MAFederal Sponsored Aw$1,102,639
The Massachusetts General Hospital Boston, MAFed/Nonfed Sponsored$1,096,260
Enplusone Biosciences Inc Watertown, MAFederal Sponsored Aw$1,051,207
The Brigham and Women's Hospital Inc Boston, MAFed/Nonfed Award$858,606
Icahn School of Medicine at Mount Sinai New York, NYFederal Sponsored Aw$260,039
Beth Israel Deaconess Medical Center Boston, MAResearch Collaborations$196,291
Trustees of Boston University Boston, MAResearch Collab$193,258
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Financial History

Multi-year comparison from IRS filings

The grant totals were reported across 12 grants in 2025, 13 in 2024, and 15 in 2023.

Figures from IRS filings, by filing year
Filing yearTotal AssetsRevenueExpensesGrants paidGrantsNet Investment Income
2025$478,867,652$63,262,538$91,488,411$9,249,93912$2,873,030
2024$512,893,468$61,613,633$85,948,150$7,337,52513$2,588,902
2023$538,779,011$310,894,989$85,046,437$7,026,60815$2,882,756
2022$165,782,005$48,462,213$73,057,969$5,675,00517$2,941,486
2021$178,608,152$47,853,271$82,969,003$12,364,20116$2,763,626
2020$225,546,330$52,451,825$78,487,395$5,141,20420$3,389,799
2019$197,654,044$204,637,925$82,107,021$5,975,05223$2,357,371

Research compiled by Grantable AI from public sources. Last updated October 2026.

Mission & Focus Areas

The institute’s stated mission is to transform healthcare, industry, and the environment by emulating the way nature builds. Its work includes developing bioinspired materials and devices, with applications spanning healthcare, manufacturing, robotics, energy, and sustainable architecture. The institute’s current platforms and initiatives include bioinspired therapeutics, diagnostics, immuno-materials, living cellular devices, molecular robotics, 3D organ engineering, sustainable futures, and synthetic biology.

The institute supports research and technology development and provides research support to academic and nonprofit medical institutions. Its 2025 grants included MIT, whose mission is to advance knowledge and educate students in science, technology, and other areas of scholarship, and the Icahn School of Medicine at Mount Sinai, whose mission includes advancing science, medicine, and health care delivery for the benefit of humanity.

Grantmaking

In filing year 2025, the institute reported 12 grants totaling $9,249,939. Grant amounts ranged from $85,528 to $1,693,161, with a median of $954,906.

The largest awards included $1,693,161 to Attivare Therapeutics Inc.; $1,375,366 to the Massachusetts Institute of Technology; $1,173,360 to Children’s Hospital Corporation; $1,102,639 to Dana-Farber Cancer Institute Inc.; and $1,096,260 to the Massachusetts General Hospital. Other recipients included EnPlusOne Biosciences Inc. ($1,051,207), Brigham and Women’s Hospital ($858,606), and Icahn School of Medicine at Mount Sinai ($260,039).

The institute’s website describes a Sponsored Research Team that helps its researchers identify funding opportunities and prepare grant applications and related materials. This describes support for the institute’s own researchers, not an application process for outside grant applicants.

Leadership & Key People

Leadership team and compensation from IRS filings

The 2025 filing lists Donald Ingber as president. Other listed officers and directors are Alan Garber, George Daley, Meredith Weenick, David Parkes, and John Shaw, directors; Angelika Fretzen, COO/Technology Translation Director; Julia Faber, clerk; Matthew Makarewicz, CFO/treasurer; and Paul Resnick, director of technology commercialization.

Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc is led by Donald Ingber, President on every filing since 2019; none of the 22 officers listed in 2025 report compensation.

Officers on the 2025 filing

  • Donald Ingber

    President

    On filings since 2019

    46 hrs/week

    No compensation reported

  • Alan Garber

    Director

    On filings since 2019

    0.5 hrs/week

    No compensation reported

  • Angelika Fretzen

    COO & Tech Trans. Director

    Technology Translation Director → Tech Translation Director, 2020

    Tech Translation Director → COO & Tech Trans. Director, 2022

    On filings since 2019

    60 hrs/week

    No compensation reported

  • George Daley

    Director

    On filings since 2019

    0.5 hrs/week

    No compensation reported

  • Hansjorg Wyss

    Director

    On filings since 2019

    0.5 hrs/week

    No compensation reported

  • James Niemi

    Senior Director, Trans. R & D

    Lead Senior Staff Engineer → Lead Staff Engineer II, 2020

    Lead Staff Engineer II → Senior Director, Trans. R & D, 2023

    On filings since 2019

    60 hrs/week

    No compensation reported

  • Kenneth Lutchen

    Director

    On filings since 2019

    0.5 hrs/week

    No compensation reported

  • Michael Super

    Director Immuno-Materials

    Lead Staff Scientist II → Director & Immuno-Materials, 2023

    Director & Immuno-Materials → Director Immuno-Materials, 2025

    On filings since 2019

    60 hrs/week

    No compensation reported

  • Molly McUsic

    Director

    On filings since 2019

    0.5 hrs/week

    No compensation reported

  • Norbert Haas

    Director

    On filings since 2019

    0.5 hrs/week

    No compensation reported

  • Philip Reilly

    Director

    Director → Directors, 2020

    Directors → Director, 2021

    On filings since 2019

    0.5 hrs/week

    No compensation reported

  • Robert Bland

    Director

    On filings since 2019

    0.5 hrs/week

    No compensation reported

  • Sandra Fenwick

    Director

    On filings since 2019

    0.5 hrs/week

    No compensation reported

  • James Gorman

    Senior Director, Trans. R & D

    Lead Staff Scientist II → Senior Director, Trans. R & D, 2022

    On filings since 2021

    60 hrs/week

    No compensation reported

  • Kenneth Carlson

    Senior Director Translational R & D

    Lead Staff Scientist II → Senior Principal Scientist, 2022

    Senior Principal Scientist → Senior Director Translational R & D, 2025

    On filings since 2021

    60 hrs/week

    No compensation reported

  • Paul Resnick

    Director of Tech Commercialization

    Senior Director of Business Development → Director of Tech Commercialization, 2025

    On filings since 2021

    No compensation reported

  • John Shaw

    Director

    On filings since 2022

    0.5 hrs/week

    No compensation reported

  • Meredith Weenick

    Director

    On filings since 2023

    0.5 hrs/week

    No compensation reported

  • David Parkes

    Director

    On filings since 2024

    0.5 hrs/week

    No compensation reported

  • Samuel Inverso

    Business Development Director Partnership

    New on the 2025 filing

    60 hrs/week

    No compensation reported

  • Julia Faber

    Clerk

    On filings since 2019

    0.5 hrs/week

    No compensation reported

  • Matthew Makarewicz

    CFO & Treasurer

    Treasurer & Sr.dir. of Finance → CFO & Treasurer, 2024

    On filings since 2022

    60 hrs/week

    No compensation reported

Former officers (14)
  • Former: Robert Cunningham (2019–2024) — Senior Director of Strategic Engmt.
  • Former: Francis Doyle (2019–2023) — Director
  • Former: Howard Stevenson (2019–2023) — Director
  • Former: Katherine Lapp (2019–2023) — Director
  • Former: Robert F. Higgins (2019–2023) — Director
  • Former: Srikant M. Datar (2019–2023) — Director
  • Former: Ayis Antoniou (2019–2022) — Former Treasurer & Administrator Director
  • Former: Richard McCullough (2019–2022) — Director
  • Former: Astrid King (2020–2022) — Dr. of Finance & Controller
  • Former: Margaret Newell (2022) — Director
  • Former: Chuan Ally Chang (2021) — Senior Director of Business Development
  • Former: Edward Doherty (2019–2020) — Lead Staff Scientist II
  • Former: Mary Tolikas (2019) — Former Operations Director
  • Former: William Blake (2019) — Business Development Lead

Data from IRS Form 990 filings, 2019–2025. "On filings since" is the earliest filing we hold that lists the person; hours are average hours per week as reported.

Frequently asked questions about Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc

How much does Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc give each year?

Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc gave $9.2M across 12 grants in 2025, according to its 2025 IRS Form 990. In 2024 it gave $7.3M across 13 grants.

What is Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc's typical grant size?

Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc's median grant in 2025 was $954,907, and its average grant was $770,828, across 12 grants on its 2025 IRS Form 990. Organizations receiving their first grant from Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc that year got $1.1M on average.

Where does Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc give grants?

Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc gives mostly in Massachusetts: 95% of the grant dollars itemized on its 2025 IRS Form 990 went to recipients there. The most frequent recipient cities were Boston, MA (6 grants).

Does Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc give general operating support?

Not in 2025: none of the 12 grants with a stated purpose on Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc's 2025 IRS Form 990 were described as general or operating support. Recurring purposes include "Fed/Nonfed Sponsored" (3 grants) and "Federal Sponsored Aw" (3 grants).

Who are Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc's largest grantees?

Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc's largest 2025 grantees include Attivare Therapeutics Inc ($1,693,161), Massachusetts Institute of Technology ($1,375,366) and Children's Hospital Corporation ($1,173,360), according to its 2025 IRS Form 990. Together they received 46% of its itemized 2025 grant dollars.

How large is Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc?

Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc reported $478.9M in total assets on its 2025 IRS Form 990. Its revenue that year was $63.3M.

What does Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc fund?

The institute’s stated mission is to transform healthcare, industry, and the environment by emulating the way nature builds. Its work includes developing bioinspired materials and devices, with applications spanning healthcare, manufacturing, robotics, energy, and sustainable architecture. See mission & focus areas ↑

How do I apply for a grant from Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc?

Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc has no public application process in the sources Grantable reviewed. Check wyss.harvard.edu for current guidelines, or contact the foundation directly before submitting a request.

What is Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc's EIN?

Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc's EIN (Employer Identification Number) is 30-0773387. IRS Form 990 filing data is available on this page for 2019–2025.

Data last updated October 2026. Sourced from IRS Form 990 filings. Research dossier generated October 2026.

Data update history

(8)

When this profile's IRS filing data changed on Grantable

  1. Updated Form 990 for fiscal year 2020 (received by the IRS May 14, 2021)
  2. Updated Form 990 for fiscal year 2021 (received by the IRS May 13, 2022)
  3. Updated Form 990 for fiscal year 2022 (received by the IRS May 11, 2023)
  4. Updated Form 990 for fiscal year 2023 (received by the IRS May 14, 2024)
  5. Updated Form 990 for fiscal year 2024 (received by the IRS May 15, 2025)
  6. Updated Form 990 for fiscal year 2019 (received by the IRS July 15, 2020)
  7. Added Form 990 for fiscal year 2025 (received by the IRS May 14, 2026)
  8. IRS filings on file for fiscal years 2019–2024

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Cite this profile

Grantable. (2026). Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc funder profile. GrantGraph. Retrieved October 5, 2026, from https://grantable.co/funders/hansjorg-wyss-institute-for-biologically-inspired-engineering-at-harvard-univ-inc-morg_3f21a8d08fff49feb552c66cbcad6db1

BibTeX
@misc{grantable_300773387_2026,
  author       = {{Grantable}},
  title        = {{Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc funder profile}},
  howpublished = {GrantGraph},
  year         = {2026},
  url          = {https://grantable.co/funders/hansjorg-wyss-institute-for-biologically-inspired-engineering-at-harvard-univ-inc-morg_3f21a8d08fff49feb552c66cbcad6db1},
  note         = {Accessed 2026-10-05. Data licensed CC BY 4.0}
}

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Figures come from Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Univ Inc's IRS filings (methodology). AI-written summaries, news items and logos are not covered by the open licence. Spot an error? Email hello@grantable.co.

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