Cancer Prevention Initiative Inc
Cancer Prevention Initiative, Inc. (CPI) is a nonprofit corporation whose mission is to accelerate the discovery and development of new medicines that prevent cancer. CPI uses its research, medical and pharmaceutical expertise to invest in first-rate science that will discover new medical methods for preventing cancer. Our strategy is to support research on prevention of inherited cancers as a path towards elimination of all cancers. CPI acts as a facilitator to ensure that good ideas can find sufficient funding to turn them into therapeutic solutions such as drugs or vaccines to prevent cancer. CPI provides financial support, guidance and expertise throughout the research and development process to help researchers use the resources (donations) for the highest possible impact.
Cancer Prevention Initiative Inc at a glance
In short: Cancer Prevention Initiative Inc gave $725K across 3 grants in 2025 (avg $242K), mostly in Texas. Source: 2025 IRS Form 990.
- Annual giving (2025)
- $725,000
- +11.5% vs 2024
- Grants made (2025)
- 3
- +50.0% vs 2024
- Average grant
- $241,667
- -25.6% vs 2024
- Median grant
- $150,000
- Total assets
- $1,927,394
- -13.4% vs 2024
- Primary geography
- Texas (79% of itemized 2025 grant dollars)
- Latest 990 filing
- Form 990, 2025 View filing
Data from IRS Form 990, 2025; updated September 2026.
How to apply to Cancer Prevention Initiative Inc
Open Grants
1 open opportunity from Cancer Prevention Initiative Inc
Who Cancer Prevention Initiative Inc funds
How this funder distributes its grants
Top Recipients
Top 3 recipients in 2025
The largest 2025 recipient was University of Texas MD Anderson Cancer Center ($450K). Together the top 3 received $725K.
Grant Size Distribution
9 grants across all recorded years
The most common grant size was in the $100–250K range: 7 grants of 9 (78%).
Geographic Focus
Where this funder awards grants
Grant Distribution by State
Share of 2025 grant dollars across all 3 itemized grants.
Cities
Giving History
Giving Over Time
Total grant dollars and number of grants per year
From 2020 to 2025, annual grant giving ranged from $200K (2023) to $725K (2025). In 2025 it made 3 grants totaling $725K.
Grants by year
Grant recipients and amounts by year
| Recipient | Purpose | Amount |
|---|---|---|
| University of Texas MD Anderson Cancer Center Houston, TX | The purpose of the Grant is for the Principal Investigator to carry out the research to develop immune interventions that could reduce the risk of Lynch Syndrome (LS)-related cancers. The goals of the project are to develop vaccines and test their potential to prevent colorectal cancer in a preclinical model of LS and to explore the colonic immune microenvironment. | $450,000 |
| Memorial Sloan Kettering Cancer Center New York, NY | This project to identify factors that influence the Loss of Heterozygosity (LOH) was initially funded in 2019. Based on the significant progress made in the project, the project was granted additional funding to continue to phase 2 in 2021 and phase 3 in 2024-2025. During phase 3, they will study allele loss under BRCA wildtype and heterozygous conditions. These studies will provide a comparative mechanistic understanding of LOH at BRCA under normal and carrier conditions. This mechanistic understanding will facilitate development of strategies to prevent LOH and thereby prevent cancer development in high-risk individuals. | $150,000 |
| University of Texas Southwestern Medical Center Dallas, TX | Scientific and administrative oversight of all Cancer Prevention Initiative programs. | $125,000 |
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Financial History
Multi-year comparison from IRS filings
| Filing year | Total Assets | Revenue | Expenses | Grants paid | Grants | Net Investment Income |
|---|---|---|---|---|---|---|
| 2025 | $1,927,394 | $778,663 | $856,539 | $725,000 | 3 | $77,180 |
| 2024 | $2,225,249 | $1,673,681 | $703,827 | $650,000 | 2 | $69,104 |
| 2023 | $821,212 | $49,585 | $74,394 | $200,000 | 1 | $49,520 |
| 2022 | $1,056,196 | $257,068 | $18,418 | — | — | $11,849 |
| 2021 | $962,671 | $151 | $308,042 | $480,000 | 3 | $16 |
| 2020 | $1,546,694 | $481,790 | $572,883 | $550,000 | 4 | $1,694 |
About Cancer Prevention Initiative Inc
Based on IRS filings
Cancer Prevention Initiative Inc is a public charity focused on Medical Research, based in Dallas, TX. IRS filing data is available from 2020 through 2025. As of 2025, the organization holds $1.9M in total assets. In 2025, it awarded 3 grants totaling $725K. Net investment income was $77K.
Focus Areas
Leadership & Key People
Officers and directors from IRS filings
Cancer Prevention Initiative Inc is led by Theodora Ross, President, Chief Scientific Officer & Trustee since 2025 (on filings since 2020); none of the 6 officers listed in 2025 report compensation.
Officers on the 2025 filing
Theodora Ross
President, Chief Scientific Officer & Trustee
President & Chief Scientific Officer → President, Chief Scientific Officer & Trustee, 2025
On filings since 2020
5 hrs/week
$50K (2021) → $0 (2025)
Howard Janzen
Board Chair, Secretary & Trustee
Board Chair → Board Chair & Chief Financial Officer, 2021
Board Chair & Chief Financial Officer → Board Chair, Secretary & Trustee, 2025
On filings since 2020
5 hrs/week
No compensation reported
Jan Livingston-Mokhtari
Trustee
On filings since 2020
1 hr/week
No compensation reported
Joi Morris
Treasurer & Trustee
Trustee → Treasurer & Trustee, 2025
On filings since 2020
6 hrs/week
No compensation reported
Kirk Patrick
Secretary & Trustee
Secretary → Secretary & Trustee, 2022
On filings since 2020
0.5 hrs/week
No compensation reported
Douglas Hager
Trustee, Senior Vice President, Project Management & Operations
On filings since 2021
10 hrs/week
No compensation reported
Former officers (2)
- Former: James Rasulo (2020) — Treasurer
- Former: Margaret Cuomo (2020) — Trustee
Data from IRS Form 990 filings, 2020–2025. "On filings since" is the earliest filing we hold that lists the person; hours are average hours per week as reported.
Compensation Overview
From 2021 IRS filing
The highest reported compensation on the 2021 filing was $50K, to Theodora Ross (President & Chief Scientific Officer).
Frequently asked questions about Cancer Prevention Initiative Inc
How much does Cancer Prevention Initiative Inc give each year?
Cancer Prevention Initiative Inc gave $725K across 3 grants in 2025, according to its 2025 IRS Form 990. In 2024 it gave $650K across 2 grants.
What is Cancer Prevention Initiative Inc's typical grant size?
Cancer Prevention Initiative Inc's median grant in 2025 was $150,000, and its average grant was $241,667, across 3 grants on its 2025 IRS Form 990.
Where does Cancer Prevention Initiative Inc give grants?
Cancer Prevention Initiative Inc gives mostly in Texas: 79% of the grant dollars itemized on its 2025 IRS Form 990 went to recipients there. The next largest state was New York (21%).
Does Cancer Prevention Initiative Inc give general operating support?
Not in 2025: none of the 3 grants with a stated purpose on Cancer Prevention Initiative Inc's 2025 IRS Form 990 were described as general or operating support.
How large is Cancer Prevention Initiative Inc?
Cancer Prevention Initiative Inc reported $1.9M in total assets on its 2025 IRS Form 990. Its revenue that year was $779K.
What is Cancer Prevention Initiative Inc?
Cancer Prevention Initiative Inc is a public charity focused on Medical Research, based in Dallas, TX. It holds $1.9M in total assets as of 2025.
What is Cancer Prevention Initiative Inc's EIN?
Cancer Prevention Initiative Inc's EIN (Employer Identification Number) is 47-3425850. IRS Form 990 filing data is available on this page for 2020–2025.
Data last updated September 2026. Sourced from IRS Form 990 filings.
Data update history
(6)
When this profile's IRS filing data changed on Grantable
- Updated Form 990 for fiscal year 2020 (received by the IRS August 22, 2021)
- Updated Form 990 for fiscal year 2021 (received by the IRS May 9, 2022)
- Updated Form 990 for fiscal year 2023 (received by the IRS May 13, 2024)
- Updated Form 990 for fiscal year 2024 (received by the IRS May 12, 2025)
- Added Form 990 for fiscal year 2025 (received by the IRS May 6, 2026)
- IRS filings on file for fiscal years 2020–2024
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Cancer Prevention Initiative Inc down — hundreds of funders to go?