Patrick & Susan Keefe Family Foundation Inc

Reynolds Charitable Foundation Trust

Chevy Chase, MD

Duke Energy Foundation

Charlotte, NC

The Duke Energy Foundation funds workforce and local economic development, disaster resilience, conservation, clean water, and economic opportunity in North Carolina, South Carolina, Florida, Ohio, Kentucky, and Indiana. Its 2024 grants had a median of $25,000; applications for grants of $20,000 or less are accepted year-round, after applicants discuss proposals with a state representative.

Vandeventer Black Foundation

Norfolk, VA

Aetna Foundation Inc

Hartford, CT

Aetna Foundation supported health and wellness, access to health care, and related community needs; its 2021 grants ranged from $5,000 to $1 million, with a median of $40,000, and went to organizations across multiple states, especially in D.C. and Connecticut. Its 2021 filing was marked final, so it appears to have ended or be winding down grantmaking; that filing said there were no restrictions on who could apply and pointed applicants to its website for application materials.

CPPS Heritage Mission Fund

Dayton, OH

The fund supports 501(c)(3) nonprofits whose work reflects the Sisters of the Precious Blood’s values, including dignity of life, healing and reconciliation, solidarity with the poor, and responses to unmet needs; it funds program start-up, operating support, expansion, capital projects, and some mini-grants. Awards ordinarily range from $5,000 to $100,000 (the 2024 median was $20,000), and grants have gone to organizations in multiple states, with Ohio receiving the largest share in 2024. Organizations must start with a Letter of Inquiry, and only those invited to continue may submit a full application.

Bristol-Myers Squibb Foundation Inc

Princeton, NJ

The Bristol-Myers Squibb Foundation supports health access and stronger health systems, with a focus on adult and pediatric cancers, blood disorders, brain health, and clinical-trial participation in the United States, Brazil, India, and ten Sub-Saharan African countries. In 2024, its median grant was about $134,000, though awards varied widely; it does not state whether it accepts unsolicited requests, and advises prospective applicants to contact the Foundation about its process.

The Blocker Foundation

Suffolk, VA

The Blocker Foundation funds 501(c)(3) nonprofits serving Hampton Roads in areas including nourishment, shelter, education, economic opportunity, and the environment. Its 2024 grants ranged from $6,140 to $250,000, with a median of about $58,000; the service area covers southeastern Virginia and three North Carolina counties. Unsolicited requests are considered through an LOI process, but applicants must first speak with foundation staff.

Southern Bank Foundation

Mount Olive, NC

Southern Bank Foundation supports a range of public-benefit organizations, with most of its 2024 grant dollars going to North Carolina and smaller shares to Virginia, Florida, and Tennessee. Its 2024 grants ranged from $300 to $125,000, with a median of $6,720. It does not limit giving to preselected organizations; its filing lists a grant request form and materials, but does not state whether unsolicited requests are accepted.

The Morris and Gwendolyn Cafritz

Washington, DC

The foundation funds arts and humanities, community services, education, environment, and health initiatives serving the Washington, DC metropolitan area, including DC and specified counties and cities in Maryland and Virginia. Its 2025 grants ranged from $100 to $1.2 million, with a median of $35,000; it prefers general operating support when possible. It accepts unsolicited requests through its online portal.

United Way of Greater Cincinnati

Cincinnati, OH

United Way of Greater Cincinnati funds community programs focused on educational success, financial empowerment and housing security, including workforce development and emergency food and shelter. Its 2025 grants ranged from $6,000 to $1.55 million, with a median of $65,000, primarily serving nine Cincinnati-area counties in Ohio, Kentucky and Indiana. It is not currently accepting general funding requests; nonprofits can join its notification list for future funding cycles.

Columbus Foundation

Columbus, OH

The Columbus Foundation supports a broad range of nonprofit work, including arts, education, health, basic needs, neighborhoods, and capacity building, primarily in central Ohio. Its 2024 grants had a median of $21,471, though amounts varied widely. Most grants are directed by donors and aren’t made through an application process, but some specific programs accept applications.

The Greater Cincinnati Foundation

Cincinnati, OH

The Greater Cincinnati Foundation funds nonprofits working on education, housing, community and cultural vibrancy, and related regional needs, with responsive grants focused on its eight-county Greater Cincinnati service area. Its 2024 median grant was $20,000, though amounts vary widely; specific opportunities include awards of up to $35,000 for Resilient Communities and up to $450,000 through the Neighborhood Development Fund. It lists RFP and letter-of-intent opportunities but does not state whether it accepts unsolicited requests.