East River Electric Power Cooperative Inc

Avera Health

Sioux Falls, SD

Avera Health supports eligible nonprofits working in health and wellness, unmet community health needs, healthy lifestyles, environmental and social initiatives, and civic or community development. Its 2025 grants ranged from $5,100 to $850,000, with a median of $17,737; funding is focused on central and eastern South Dakota and nearby parts of Minnesota, Iowa, North Dakota, and Nebraska. It accepts requests through its Community Partnership/Donation Request process and asks applicants to use its form.

The McConnell Foundation

Redding, CA

The McConnell Foundation funds eligible nonprofits, public education institutions, and government entities in Modoc, Shasta, Siskiyou, Tehama, and Trinity Counties, as well as projects in Nepal and Laos, across areas including education, community vitality, health, arts, recreation, and social services. In 2024, grants had a median of $7,450 and ranged from $75 to about $3.46 million; eligible projects in the five-county area may request up to $50,000 through the Community Foundation of the North State. The profile does not state whether the Foundation accepts unsolicited requests directly.

Sioux Falls Area Community Foundation Inc

Sioux Falls, SD

The Sioux Falls Area Community Foundation funds local charitable, educational, cultural, religious, community-development, and environmental needs, including new programs and nonprofit capacity building, primarily in the Sioux Falls area and surrounding communities. Its 2025 grants had a median of $25,000, though awards varied widely; organizations may submit a Letter of Inquiry for Community Fund Grants.

First Interstate BancSystem Foundation

Billings, MT

The First Interstate BancSystem Foundation funds poverty reduction, youth development, financial education, and community development, as well as civic, arts, education, health, human services, and sustainability efforts in communities served by First Interstate Bank across 10 states. Its 2025 grants had a median award of $2,500, though amounts varied widely; the stated minimum grant is $2,500. Organizations can submit grant requests online, which are traditionally reviewed monthly, but grants must be recommended by a local First Interstate branch.

The Eric and Wendy Schmidt Fund for Strategic Innovation

Palo Alto, CA

The fund supports scientific research, education, emerging technology, youth talent development, and public-interest work addressing challenges such as climate, health, economic opportunity, and security. Its 2024 grants ranged from $1,000 to $12.5 million, with a median of $100,000, and supported organizations in several U.S. states, including Massachusetts and California, as well as international recipients. It funds only preselected charitable organizations and does not accept unsolicited requests.

Larson Foundation

Sioux Falls, SD

The Larson Foundation supports eligible charitable organizations, educational institutions, and government units working to improve quality of life, with recent grants spanning housing, youth programs, education, and family services. It gives primarily in South Dakota, with a typical grant around $30,000 (2025 median; awards ranged from $4,500 to $260,000). Applicants must complete a grant request form, so it accepts requests; deadlines are March 1 and September 1, subject to change.

Madison Community Hospital

Madison, SD

Madison regional health system serves as a community health focal point through the provision of compassionate, quality, and innovative care.

Krueger George W Tua

Saint Louis, MO

Valley Queen Charitable Foundation

Milbank, SD

Valley Queen Charitable Foundation supports community, educational, industry, and humanitarian initiatives, with most funding going to South Dakota and some to Minnesota. Its 2025 grants ranged from $100 to $107,750, with a median of $1,500. It accepts requests year-round; organizations can request an application by calling the foundation.

South Dakota Community Foundation

Pierre, SD

The South Dakota Community Foundation funds nonprofits and charitable projects in areas including education, health, human services, culture, and economic development, primarily benefiting South Dakota communities. Its 2024 grants had a median of $18,562, while 2026 Beyond Idea Grants range from $5,000 to $100,000 per year. Eligible nonprofits can apply for South Dakota Fund and Beyond Idea Grants through its online portal.

Sanford Group Return

Sioux Falls, SD

Sanford Group Return funds health care access and outcomes, community wellbeing, workforce and education, and related community needs, including health professions education and research. In 2024, its median grant was $24,900, with awards ranging from $5,500 to $3.6 million; giving was concentrated in South Dakota, North Dakota, and Minnesota. Its Community Dividend Fund accepts online funding requests in South Dakota, Iowa, Minnesota, Montana, Nebraska, North Dakota, and Wyoming; whether unsolicited requests are accepted is not stated.