Cure Sanfilippo Foundation
To accelerate scientific development and access to a cure or therapeutic options for all affected by Sanfilippo syndrome, drive advocacy to improve care and outcomes, and empower families with information, guidance, and support to navigate the journey.
Cure Sanfilippo Foundation at a glance
In short: Cure Sanfilippo Foundation gave $256K across 4 grants in 2024 (avg $64K), mostly in California. Source: 2024 IRS Form 990.
- Annual giving (2024)
- $255,541
- -44.0% vs 2023
- Grants made (2024)
- 4
- -42.9% vs 2023
- Average grant
- $63,885
- -1.9% vs 2023
- Median grant
- $46,521
- Total assets
- $13,871,255
- +23.9% vs 2023
- Primary geography
- California (64% of itemized 2024 grant dollars)
- Latest 990 filing
- Form 990, 2024 View filing
Data from IRS Form 990, 2024; updated September 2026.
How to apply to Cure Sanfilippo Foundation
Open Grants
3 open opportunities from Cure Sanfilippo Foundation
Cure Sanfilippo Foundation: ADVANCE Sanfilippo Funding Mechanism
Cure Sanfilippo Foundation
Amount
Varies
Deadline
Deadline not published
Cure Sanfilippo Foundation: Fellowship Award Mechanism
Cure Sanfilippo Foundation
Amount
Varies
Deadline
Deadline not published
Cure Sanfilippo Foundation: Pilot Funding Mechanism
Cure Sanfilippo Foundation
Amount
Varies
Deadline
Deadline not published
Who Cure Sanfilippo Foundation funds
How this funder distributes its grants
Top Recipients
Top 3 recipients in 2024
The largest 2024 recipient was Regents of UC - San Diego ($163K across 2 grants). Together the top 3 received $256K.
Grant Size Distribution
36 grants across all recorded years
The most common grant size was under $50K: 13 grants of 36 (36%).
Geographic Focus
Where this funder awards grants
Grant Distribution by State
Share of 2024 grant dollars across all 4 itemized grants.
Cities
How Cure Sanfilippo Foundation gives
- Giving fell 84% from 2021 to 2024. Method
From the foundation's IRS Form 990 filings. Methodology.
Giving History
Giving Over Time
Total grant dollars and number of grants per year
From 2020 to 2024, annual grant giving ranged from $256K (2024) to $2.5M (2020). In 2024 it made 4 grants totaling $256K.
Grants by year
Grant recipients and amounts by year
| Recipient | Purpose | Amount |
|---|---|---|
| Regents of UC - San Diego La Jolla, CA | Treating Mucopolysaccharidosis | $120,000 |
| University of Georgia Athens, GA | Peropheral Neural Stem Cell Models | $49,976 |
| Regents of UC - San Diego La Jolla, CA | Blood-based biomarkers | $43,065 |
| Clemson University Clemson, SC | Neuroprotective peptides for treatm | $42,500 |
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Financial History
Multi-year comparison from IRS filings
| Filing year | Total Assets | Revenue | Expenses | Grants paid | Grants | Net Investment Income |
|---|---|---|---|---|---|---|
| 2024 | $13,871,255 | $2,781,149 | $1,572,959 | $255,541 | 4 | $580,274 |
| 2023 | $11,198,610 | $2,106,392 | $1,292,685 | $456,067 | 7 | $292,943 |
| 2022 | $9,625,770 | $2,707,445 | $2,287,097 | $1,239,902 | 7 | $483,599 |
| 2021 | $10,337,575 | $2,229,880 | $2,586,338 | $1,583,407 | 10 | $186,864 |
| 2020 | $10,163,332 | $2,083,251 | $3,140,290 | $2,520,506 | 8 | $233,157 |
About Cure Sanfilippo Foundation
Based on IRS filings
Cure Sanfilippo Foundation is a public charity focused on Medical Research, based in Columbia, SC. IRS filing data is available from 2020 through 2024. As of 2024, the organization holds $13.9M in total assets. In 2024, it awarded 4 grants totaling $256K. Net investment income was $580K.
Focus Areas
Leadership & Key People
Officers and directors from IRS filings
Cure Sanfilippo Foundation is led by Glenn O'Neill, Exe Director & President since 2021 (on filings since 2020); 3 of 10 officers listed in 2024 are compensated.
Officers on the 2024 filing
Glenn O'Neill
Exe Director & President
Executive Director → Exe Director & President, 2021
On filings since 2020
50 hrs/week
$133K (2020) → $139K (2024)
Daniel Fraley
Board Chair
On filings since 2020
2 hrs/week
No compensation reported
Ben Von Wong
Director
On filings since 2020
2 hrs/week
$8K (2022) → $0 (2024)
Adam Shaywitz
Director
On filings since 2020
2 hrs/week
No compensation reported
Faith McAngus
Director
On filings since 2020
2 hrs/week
No compensation reported
Jessica Haywood
Director
On filings since 2023
2 hrs/week
No compensation reported
Mike Lykes
Director
New on the 2024 filing
2 hrs/week
No compensation reported
Cara O'Neill
Chief Science
On filings since 2020
40 hrs/week
$78K (2020) → $125K (2024)
Katie Walton
Vice President
On filings since 2020
40 hrs/week
$107K (2020) → $118K (2024)
Shelby Leonardi
Secretary
On filings since 2020
2 hrs/week
No compensation reported
Former officers (2)
- Former: Valerie Byers (2020–2023) — Director
- Former: Rachel Best (2020) — Director
Data from IRS Form 990 filings, 2020–2024. "On filings since" is the earliest filing we hold that lists the person; hours are average hours per week as reported.
Compensation Overview
From 2024 IRS filing
The highest reported compensation on the 2024 filing was $139K, to Glenn O'Neill (Exe Dir/Pres). 3 officers or directors reported compensation on that filing.
Frequently asked questions about Cure Sanfilippo Foundation
How much does Cure Sanfilippo Foundation give each year?
Cure Sanfilippo Foundation gave $256K across 4 grants in 2024, according to its 2024 IRS Form 990. In 2023 it gave $456K across 7 grants.
What is Cure Sanfilippo Foundation's typical grant size?
Cure Sanfilippo Foundation's median grant in 2024 was $46,521, and its average grant was $63,885, across 4 grants on its 2024 IRS Form 990.
Where does Cure Sanfilippo Foundation give grants?
Cure Sanfilippo Foundation gives mostly in California: 64% of the grant dollars itemized on its 2024 IRS Form 990 went to recipients there. The next largest states were Georgia (20%) and South Carolina (17%). The most frequent recipient cities were La Jolla, CA (2 grants).
Does Cure Sanfilippo Foundation give general operating support?
Not in 2024: none of the 4 grants with a stated purpose on Cure Sanfilippo Foundation's 2024 IRS Form 990 were described as general or operating support.
How large is Cure Sanfilippo Foundation?
Cure Sanfilippo Foundation reported $13.9M in total assets on its 2024 IRS Form 990. Its revenue that year was $2.8M.
What is Cure Sanfilippo Foundation?
Cure Sanfilippo Foundation is a public charity focused on Medical Research, based in Columbia, SC. It holds $13.9M in total assets as of 2024.
What is Cure Sanfilippo Foundation's EIN?
Cure Sanfilippo Foundation's EIN (Employer Identification Number) is 46-4322131. IRS Form 990 filing data is available on this page for 2020–2024.
Data last updated September 2026. Sourced from IRS Form 990 filings.
Data update history
(6)
When this profile's IRS filing data changed on Grantable
- Updated Form 990 for fiscal year 2020 (received by the IRS February 17, 2022)
- Updated Form 990 for fiscal year 2021 (received by the IRS November 14, 2022)
- Updated Form 990 for fiscal year 2022 (received by the IRS November 14, 2023)
- Updated Form 990 for fiscal year 2023 (received by the IRS November 11, 2024)
- Updated Form 990 for fiscal year 2024 (received by the IRS November 11, 2025)
- IRS filings on file for fiscal years 2020–2024
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