Chan Zuckerberg Biohub Inc
Chan Zuckerberg Biohub Inc is a San Francisco-based public charity that supports biomedical research and scientific tools intended to accelerate progress toward curing, preventing, or managing disease. Formed in 2016, it works through research institutes and awards to university-based investigators.
Chan Zuckerberg Biohub Inc at a glance
In short: Chan Zuckerberg Biohub Inc gave $40.4M across 10 grants in 2024 (avg $4.0M), mostly in California. 70% of 2024 grantees were new. Source: 2024 IRS Form 990.
- Annual giving (2024)
- $40,382,790
- +24.8% vs 2023
- Grants made (2024)
- 10
- +42.9% vs 2023
- Average grant
- $4,038,279
- -12.7% vs 2023
- Median grant
- $2,847,802
- Total assets
- $1,477,092,189
- -0.2% vs 2023
- New grantees (estimate)
- 70% first-time grantees (7 of 10, 2024; small sample)
- Primary geography
- California (73% of itemized 2024 grant dollars)
- Latest 990 filing
- Form 990, 2024 View filing
Data from IRS Form 990, 2024; updated September 2026. New grantees are estimated by matching recipient names across years (methodology).
How to apply to Chan Zuckerberg Biohub Inc
- Contact
Mailing address: 499 Illinois St, San Francisco, CA 94158
Phone: (415) 549-3300
Website: https://czbiohub.org
Application details from Grantable's research on the foundation's public materials; confirm on its website before applying.
Open Grants
1 open opportunity from Chan Zuckerberg Biohub Inc
Who Chan Zuckerberg Biohub Inc funds
How this funder distributes its grants
Top Recipients
Top 10 recipients in 2024
The largest 2024 recipient was Regents of the University of California San Francisco ($12.3M). Together the top 10 received $40.4M.
Grant Size Distribution
26 grants across all recorded years
The most common grant size was $5M or more: 13 grants of 26 (50%).
Geographic Focus
Where this funder awards grants
In 2024, grant dollars went to recipients in California (73%), Illinois (21%), New York (4%), and Connecticut (1%). The largest awards were to institutions in California and Illinois. The New York Investigator Award program described in the FAQ is restricted to faculty at Columbia, Rockefeller, or Yale, with funds distributed to those universities.
Grant Distribution by State
Share of 2024 grant dollars across all 10 itemized grants.
Cities
Is Chan Zuckerberg Biohub Inc open to new grantees?
70%
first-time grantees, 2024
In 2024, 7 of 10 grantees (70%) were first-time recipients. With only 10 grantees, that is a small sample: one grantee more or less moves the share by about 10 points. First grants averaged $4.7M; repeat grants $2.4M. How we count
Medians: $3M first-time, $2.8M repeat.
Estimate from itemized grant lists in IRS Form 990 filings (2020–2024). Recipient names are matched across years, so a renamed or misspelled grantee can look new; grants to individuals are left out. Methodology.
Giving History
Giving Over Time
Total grant dollars and number of grants per year
From 2020 to 2024, annual grant giving ranged from $21.1M (2021) to $40.4M (2024). In 2024 it made 10 grants totaling $40.4M.
Grants by year
Grant recipients and amounts by year
| Recipient | Purpose | Amount |
|---|---|---|
| Regents of the University of California San Francisco San Francisco, CA | Scientific and Medical Research | $12,257,389 |
| The Board of Trustees of the Leland Stanford Junior University Redwood City, CA | Scientific and Medical Research | $11,626,018 |
| Regents of the University of California at Berkeley Berkeley, CA | Scientific and Medical Research | $5,535,784 |
| University of Illinois Foundation Champaign, IL | Scientific and Medical Research | $2,973,388 |
| University of Chicago Chicago, IL | Scientific and Medical Research | $2,868,865 |
| Northwestern University Evanston, IL | Scientific and Medical Research | $2,826,739 |
| The Trustees of Columbia University in the City of New York New York, NY | Scientific and Medical Research | $1,442,193 |
| Yale University New Haven, CT | Scientific and Medical Research | $434,943 |
| The Rockefeller University New York, NY | Scientific and Medical Research | $217,471 |
| University of California Berkeley Foundation Berkeley, CA | Scientific and Medical Research | $200,000 |
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Financial History
Multi-year comparison from IRS filings
| Filing year | Total Assets | Revenue | Expenses | Grants paid | Grants | Net Investment Income |
|---|---|---|---|---|---|---|
| 2024 | $1,477,092,189 | $99,552,025 | $142,410,025 | $40,382,790 | 10 | $6,102,390 |
| 2023 | $1,479,585,206 | $1,290,610,523 | $108,026,488 | $32,363,671 | 7 | $4,264,016 |
| 2022 | $271,112,430 | $16,409,981 | $90,813,707 | $29,060,304 | 3 | $891,383 |
| 2021 | $338,316,919 | $10,314,755 | $73,821,019 | $21,070,869 | 3 | $34,766 |
| 2020 | $404,074,181 | $14,019,977 | $77,357,507 | $24,709,945 | 3 | $317,759 |
Research compiled by Grantable AI from public sources. Last updated September 2026.
Mission & Focus Areas
The organization states its mission is to accelerate science in order to cure, prevent, or manage all diseases by the end of the 21st century. Its 2024 filing describes research in cryogenic electron tomography and open-access data, zebrafish development, immune-cell behavior, and implantable sensors for monitoring inflammation-related proteins.
In 2024, all ten itemized grants were designated for scientific and medical research. The recipients included universities and university-affiliated organizations. For example, the University of Chicago describes its mission as advancing knowledge and fostering a community of scholars and students; Northwestern University describes a commitment to teaching, research, and student growth; and the University of Illinois Foundation says it administers private gifts to benefit the University of Illinois System.
Grantmaking
In filing year 2024, Biohub reported 10 grants totaling $40,382,790. Grant amounts ranged from $200,000 to $12,257,389, with a median of $2,847,802. The largest awards went to the Regents of the University of California, San Francisco ($12,257,389), the Board of Trustees of the Leland Stanford Junior University ($11,626,018), and the Regents of the University of California at Berkeley ($5,535,784); each was for scientific and medical research.
Biohub’s New York Investigator Award FAQ describes a cycle offering up to eight awards to faculty affiliated with Columbia University, Rockefeller University, or Yale University. Awards are distributed only to those partner universities; collaborators at non-partner institutions cannot receive sub-awards through the program. The FAQ says proposals should present innovative, reasonably feasible, high-risk, high-reward ideas aligned with the program’s mission. Required materials include a research title and summary, a three-page proposal, a CV or NIH-style biosketch, a bibliography, three relevant publications (preprints accepted), and a signed statement of support from a division or department chair. The FAQ also says proposals from other institutions may be retained for later review. These details describe the cycle covered by the FAQ; it does not state a deadline.
The filing says investigator-award funds are provided to the recipient universities under a master collaboration agreement, restricted to the award’s purpose, and subject to written research reports. Universities disburse funds under their own policies. Biohub may also make small discretionary research gifts directly to recipients, sometimes without a written proposal and with limited or no post-grant review.
Leadership & Key People
Leadership team and compensation from IRS filings
The 2024 filing lists Stephen Quake as president and director. Joseph DeRisi is listed as a director and as president of CZB SF, a disregarded entity of Biohub; the filing explains that he was reported as an officer to reflect that entity role. Other directors listed are Cori Bargmann, Mark Zuckerberg, Mike Schroepfer, Paul Alivisatos, Priscilla Chan, Reid Hoffman, Sam Altman, and Sam Hagwood. The filing states that directors are not compensated in their capacity as directors.
Chan Zuckerberg Biohub Inc is led by Joseph Derisi, Director & President Czb Sf since 2023 (on filings since 2020); 11 of 22 officers listed in 2024 are compensated.
Officers on the 2024 filing
Joseph Derisi
Director & President Czb Sf
Co-President → Co-President & Director, 2022
Co-President & Director → Director & President Czb Sf, 2023
On filings since 2020
40 hrs/week
$909K (2020) → $904K (2024)
Andrea Califano
President & Czb Ny
President & Cz Biohub Ny → President & Czb Ny, 2024
On filings since 2023
40 hrs/week
$282K (2023) → $856K (2024)
Matthias Haury
COO, Acting Executive Director & Czii
On filings since 2023
40 hrs/week
$411K (2023) → $859K (2024)
Shana Kelley
President & Czb Chicago
On filings since 2023
40 hrs/week
$600K (2023) → $819K (2024)
Stephen Quake
President & Director
On filings since 2023
10 hrs/week
$302K (2023) → $303K (2024)
Bridget Carragher
Founding Technical Director & Czii
On filings since 2023
40 hrs/week
$377K (2023) → $782K (2024)
Clinton Potter
Founding Technical Director & Czii
On filings since 2023
40 hrs/week
$374K (2023) → $780K (2024)
David Andrew Agard
Founding Technical Director & Czii
Founding Scientific Director & Czii → Founding Technical Director & Czii, 2024
On filings since 2023
40 hrs/week
$375K (2023) → $775K (2024)
Cori Bargmann
Director
On filings since 2020
2 hrs/week
No compensation reported
Mark Zuckerberg
Director
On filings since 2020
2 hrs/week
No compensation reported
Priscilla Chan
Director
On filings since 2020
2 hrs/week
No compensation reported
Reid Hoffman
Director
On filings since 2020
2 hrs/week
No compensation reported
Mike Schroepfer
Director
On filings since 2023
2 hrs/week
No compensation reported
Paul Alivisatos
Director
On filings since 2023
2 hrs/week
No compensation reported
Sam Altman
Director
On filings since 2023
2 hrs/week
No compensation reported
Sam Hagwood
Director
New on the 2024 filing
2 hrs/week
No compensation reported
Victor Colunga
CFO & Treasurer
On filings since 2020
40 hrs/week
$714K (2020) → $316K (2024)
Sandra L. Schmid
Chief Scientific Officer & Czb Sf
Chief Scientific Officer → Chief Scientific Officer & Czb Sf, 2023
On filings since 2021
40 hrs/week
$563K (2021) → $759K (2024)
Melinda Griffith
Secretary, COO, Counsel & Czb Sf
Secretary, Czb Network, Clo & Czb Sf → Secretary, COO, Counsel & Czb Sf, 2024
On filings since 2023
40 hrs/week
$718K (2023) → $733K (2024)
Ben Roh
CFO
New on the 2024 filing
20 hrs/week
No compensation reported
Marc Malandro
COO
New on the 2024 filing
20 hrs/week
No compensation reported
Sandy Yao
Secretary & Clo
New on the 2024 filing
20 hrs/week
No compensation reported
Former officers (24)
- Former: Annette Parent (2020–2023) — Lead Ip Counsel & Czb Sf
- Former: Astrid Ho (2020–2023) — Controller
- Former: Jim Karkanias (2020–2023) — Chief Technology Officer · Filing note: Ended 12/2022
- Former: John Hennessy (2020–2023) — Director
- Former: Rafael Gomez-Sjoberg (2020–2023) — Chief Techology Officer & Czb Sf
- Former: Sonya Zilka (2020–2023) — Chief People Officer
- Former: William Burkholder (2020–2023) — Director, Scientific Prgm Management & Czb Sf
- Former: Rosio Alvarez (2021–2023) — Chief Information Officer
- Former: Craig Kapfer (2022–2023) — Senior Director & Scientific Computing
- Former: Amy E. Herr (2023) — Chief Tech Officer & Czb Network
- Former: Christopher Chin (2023) — Network Security Principal Engr
- Former: Sam Hawgood (2023) — Director
- Former: Gajus Worthington (2020–2022) — Chief Operating Officer · Filing note: Ended 122
- Former: Steve Quake (2020–2022) — Co-President & Director
- Former: Cristina Tato (2021–2022) — Director & Rapid Response Team
- Former: Amy E. Herr Start (2022) — Chief Technology Officer & Cz Biohub Network
- Former: Mandana Asghamejad (2022) — Chief Operating Officer
- Former: Melinda Griffith Start (2022) — Chief Legal Officer & Secretary
- Former: Greg Huber (2021) — Group Leader II
- Former: Maureen Sheehy Ends (2021) — Secretary & Legal Counsel
- Former: Sonya Zilka Starts (2021) — Chief People Officer
- Former: Joshua E. Elias-Merriman (2020) — Platform Leader
- Former: Maureen Sheehy (2020) — Secretary & Legal Counsel
- Former: Sandra L. Schmid Start (2020) — Chief Scientific Officer
Data from IRS Form 990 filings, 2020–2024. "On filings since" is the earliest filing we hold that lists the person; hours are average hours per week as reported.
Compensation Overview
From 2024 IRS filing
The highest reported compensation on the 2024 filing was $904K, to Joseph Derisi (Director, President CZB SF (Key Emp)). 11 officers or directors reported compensation on that filing.
Frequently asked questions about Chan Zuckerberg Biohub Inc
How much does Chan Zuckerberg Biohub Inc give each year?
Chan Zuckerberg Biohub Inc gave $40.4M across 10 grants in 2024, according to its 2024 IRS Form 990. In 2023 it gave $32.4M across 7 grants.
What is Chan Zuckerberg Biohub Inc's typical grant size?
Chan Zuckerberg Biohub Inc's median grant in 2024 was $2,847,802, and its average grant was $4,038,279, across 10 grants on its 2024 IRS Form 990. Organizations receiving their first grant from Chan Zuckerberg Biohub Inc that year got $4.7M on average.
Where does Chan Zuckerberg Biohub Inc give grants?
Chan Zuckerberg Biohub Inc gives mostly in California: 73% of the grant dollars itemized on its 2024 IRS Form 990 went to recipients there. The next largest state was Illinois (21%). The most frequent recipient cities were Berkeley, CA (2 grants) and New York, NY (2 grants).
Does Chan Zuckerberg Biohub Inc give general operating support?
Not in 2024: none of the 10 grants with a stated purpose on Chan Zuckerberg Biohub Inc's 2024 IRS Form 990 were described as general or operating support. Recurring purposes include "Scientific and Medical Research" (10 grants).
Who are Chan Zuckerberg Biohub Inc's largest grantees?
Chan Zuckerberg Biohub Inc's largest 2024 grantees include Regents of the University of California San Francisco ($12,257,389), The Board of Trustees of the Leland Stanford Junior University ($11,626,018) and Regents of the University of California at Berkeley ($5,535,784), according to its 2024 IRS Form 990. Together they received 73% of its itemized 2024 grant dollars.
How large is Chan Zuckerberg Biohub Inc?
Chan Zuckerberg Biohub Inc reported $1.5B in total assets on its 2024 IRS Form 990. Its revenue that year was $99.6M.
What does Chan Zuckerberg Biohub Inc fund?
The organization states its mission is to accelerate science in order to cure, prevent, or manage all diseases by the end of the 21st century. See mission & focus areas ↑
How do I apply for a grant from Chan Zuckerberg Biohub Inc?
Chan Zuckerberg Biohub Inc has no public application process in the sources Grantable reviewed. Check czbiohub.org for current guidelines, or contact the foundation directly before submitting a request.
What is Chan Zuckerberg Biohub Inc's EIN?
Chan Zuckerberg Biohub Inc's EIN (Employer Identification Number) is 81-1669175. IRS Form 990 filing data is available on this page for 2020–2024.
Data last updated September 2026. Sourced from IRS Form 990 filings. Research dossier generated September 2026.
Data update history
(6)
When this profile's IRS filing data changed on Grantable
- Updated Form 990 for fiscal year 2020 (received by the IRS November 12, 2021)
- Updated Form 990 for fiscal year 2021 (received by the IRS November 14, 2022)
- Updated Form 990 for fiscal year 2022 (received by the IRS November 14, 2023)
- Updated Form 990 for fiscal year 2023 (received by the IRS November 14, 2024)
- Updated Form 990 for fiscal year 2024 (received by the IRS November 17, 2025)
- IRS filings on file for fiscal years 2020–2024
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Cite this profile
Grantable. (2026). Chan Zuckerberg Biohub Inc funder profile. GrantGraph. Retrieved October 4, 2026, from https://grantable.co/funders/chan-zuckerberg-biohub-inc-morg_62fcbb6cecd9442c99af186b333542d1
BibTeX
@misc{grantable_811669175_2026,
author = {{Grantable}},
title = {{Chan Zuckerberg Biohub Inc funder profile}},
howpublished = {GrantGraph},
year = {2026},
url = {https://grantable.co/funders/chan-zuckerberg-biohub-inc-morg_62fcbb6cecd9442c99af186b333542d1},
note = {Accessed 2026-10-04. Data licensed CC BY 4.0}
}The figures on this page are open data under CC BY 4.0: reuse them with credit to Grantable and a link. Download the data.
Figures come from Chan Zuckerberg Biohub Inc's IRS filings (methodology). AI-written summaries, news items and logos are not covered by the open licence. Spot an error? Email hello@grantable.co.
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