RFA- Studies Addressing Clinically Relevant Questions About Ketones And The Use Of Continuous Ketone Monitoring In Type 1 Diabetes Grant

RFA- Studies Addressing Clinically Relevant Questions About Ketones And The Use Of Continuous Ketone Monitoring In Type 1 Diabetes Grant

Status: ACTIVE
Funder: Breakthrough T1D ( Formally JDRF International)
Amount: Up to US $1,500,000
Last Updated: September 16, 2025

Summary

Breakthrough T1D is inviting studies that address clinically relevant questions about ketones and the use of continuous ketone monitoring (CKM) in type 1 diabetes. As CKMs provide continuous data, they can enhance our understanding of ketone dynamics and their implications for diabetes management and DKA prevention. This initiative aims to foster innovative research that can lead to improved treatments and outcomes for individuals living with type 1 diabetes.

Overview

Breakthrough T1D Founded in 1970 by families whose loved ones had been diagnosed with type 1 diabetes (T1D), Breakthrough T1D is a tax-exempt nonprofit 501(c)3 organization. We are opening doors that were once closed by T1D diagnosis. We lead the way to more effective solutions by connecting the brightest minds to advance treatments, influence policy, and improve access to care.​ By driving innovation forward, Breakthrough T1D will make type 1 diabetes a condition of the past. Studies addressing clinically relevant questions about ketones and the use of continuous ketone monitoring in type 1 diabetes Purpose Circulating ketones are clinically relevant metabolites in type 1 diabetes (T1D). To date, most of our knowledge about ketones in T1D has come from point-of-care blood and urine ketone measurements, which provide only snapshots in time and lack the temporal resolution needed to fully understand ketone dynamics. Today, emerging continuous ketone monitors (CKMs) allow us to answer questions we never could before about the pathophysiology of T1D and its complications, DKA prevention, and other topics. Breakthrough T1D invites letters of intent for studies addressing clinically relevant questions about ketones and the use of CKM in T1D.

Eligibility

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