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Breakthrough T1D- Innovative Awards Grant

Breakthrough T1D

Funding Amount

Up to US $200,000

Deadline

Deadline not published

Grant Type

Foundation

Overview

The Breakthrough T1D Innovative Awards provide seed funding for groundbreaking research aimed at transforming the understanding and treatment of type 1 diabetes. These awards support highly innovative projects that may not require preliminary data but must present plausible and testable hypotheses. With a maximum funding of $200,000 for one year, proposals should focus on significant questions that challenge existing paradigms and lead to high-risk, high-reward discoveries.

Breakthrough T1D provides seed funding for highly innovative, high-risk-high-reward research with significant potential to accelerate the mission of Breakthrough T1D. Proposals should address key outstanding questions and have the potential to lead to a challenge or a change in the current paradigm or conventional wisdom and/or lead to a groundbreaking discovery. Preliminary data is not required in the proposal, but the underlying concept, premise, or hypothesis must be plausible and testable, and the proposal must be focused with a well-defined goal that is achievable within the timeframe and amount of the award.
Specific information regarding Breakthrough T1D’s Research Strategy can be found here.The Innovative Grant Mechanism is not intended to support proposals aiming to incrementally advance existing hypotheses or ongoing areas of research, or proposals with the sole goal of generating novel reagents or resources. The concept does not require preliminary evidence in T1D but must be applicable to T1D. Central hypothesis should be justified in the proposed research plan, budget, and timeline.
TERMS OF THE AWARD
Innovative grants provide one year of support for a maximum of USD 200,000.00 which includes 10% indirect costs. These grants are not renewable. Final progress and expenditure reports are due within 75 days following the close of the award.

What Breakthrough T1D actually gave

Source: IRS Form 990, 2025

Grants in 2025
100
Total given
$79.32M
Median grant
$378K
Range
$25K–$7.28M
  • By dollars: Massachusetts 21%, California 13%, Florida 7%. Top recipient cities: Boston, MA; New York, NY; Seattle, WA.
  • 0% of grants with a stated purpose were for general or operating support.
  • 16% of recipients were new grantees, not repeat recipients.

Example grants

  • University of Massachusetts Medical School · Worcester, MA

    T1d research

    $7.28M

  • The Regents of the University of California San Francisco · San Francisco, CA

    T1d research

    $5.4M

  • The University of Chicago · Chicago, IL

    T1d research

    $4.12M

  • Regents of the University of Colorado · Denver, CO

    T1d research

    $3.58M

  • University of Florida · Gainesville, FL

    T1d research

    $3.13M

IRS Form 990, 2025. Amounts as reported by the funder. Full 990 history →

Focus Areas & Funding Uses

Fields of Work

  • Science research

Categories

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