Breakthrough T1D logo

In vitro Disease Modeling: Type I Diabetes-on-a-Chip Platforms for Translational Research Grant

Breakthrough T1D

Funding Amount

Up to US $300,000

Deadline

Deadline not published

Grant Type

Foundation

Can we apply?

Check your organization against each line. Taken from the listing; confirm with the funder's guidelines.

Required status

  • 501(c)(3) tax-exempt status

Overview

Breakthrough T1D is offering a funding opportunity focused on advancing innovative organoid and organ-on-a-chip models for Type I Diabetes (T1D). This initiative aims to enhance and validate in vitro models that are relevant to human biology, facilitating the evaluation of pharmacological and genetic interventions. By doing so, it seeks to accelerate the translation of these models into clinical research. Grants of up to $300,000 are available for academic and industry partners over a one-year period.

Note: An approved Letter of Intent (LOI) is required prior to the submission of a full proposal. The deadlines are indicated above.
Breakthrough T1D
Founded in 1970 by families whose loved ones had been diagnosed with type 1 diabetes (T1D), Breakthrough T1D is a tax-exempt nonprofit 501(c)3 organization.
We lead the way to more effective solutions by connecting the brightest minds to advance treatments, influence policy, and improve access to care.​ By driving innovation forward, Breakthrough T1D will make type 1 diabetes a condition of the past.
In vitro Disease Modeling: Type I Diabetes-on-aChip Platforms for Translational Research
Summary
Breakthrough T1D is launching a new funding opportunity to support advancement of cuttingedge organoid- and organ on a chip-based disease models of Type I Diabetes (T1D).
This initiative aims to validate and refine existing human-relevant in vitro models of T1D as tools for evaluation of pharmacological and genetic interventions with the goal of accelerating translation to clinical studies.
This Request for Applications (RFA) will provide grants to academic investigators and industry partners of up to $300,000 over one year.

What Breakthrough T1D actually gave

Source: IRS Form 990, 2025

Grants in 2025
100
Total given
$79.32M
Median grant
$378K
Range
$25K–$7.28M
  • By dollars: Massachusetts 21%, California 13%, Florida 7%. Top recipient cities: Boston, MA; New York, NY; Seattle, WA.
  • 0% of grants with a stated purpose were for general or operating support.
  • 16% of recipients were new grantees, not repeat recipients.

Example grants

  • University of Massachusetts Medical School · Worcester, MA

    T1d research

    $7.28M

  • The Regents of the University of California San Francisco · San Francisco, CA

    T1d research

    $5.4M

  • The University of Chicago · Chicago, IL

    T1d research

    $4.12M

  • Regents of the University of Colorado · Denver, CO

    T1d research

    $3.58M

  • University of Florida · Gainesville, FL

    T1d research

    $3.13M

IRS Form 990, 2025. Amounts as reported by the funder. Full 990 history →

Focus Areas & Funding Uses

Fields of Work

  • Science research

Categories

Browse similar grants by category

Related Grants

Open grants from this funder and similar programs

Your AI grants department

Ready to apply for In vitro Disease Modeling: Type I Diabetes-on-a-Chip Platforms for Translational Research Grant?

Grantable helps you assess fit, draft narratives, and track deadlines — so you can submit stronger applications, faster.

You found In vitro Disease Modeling: Type I Diabetes-on-a-Chip Platforms for Translational Research Grant. Now let's win it.

Start writing