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Pathways for Hope Pilot Grant

THE ASSOCIATION FOR FRONTOTEMPORAL

Foundation Annual Grants for Science Research
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Funding Amount

Varies

Deadline

Rolling / Open

Grant Type

foundation

Overview

Pathways for Hope Pilot Grant

Funder: The Association for Frontotemporal Degeneration (AFTD)

Program Status: Active

Geographic Scope: Not specified; appears to be open to researchers internationally

Focus Areas:

  • Early-career researchers

  • New research ideas in FTD

  • Studies on genetic factors influencing FTD onset and resilience

  • Research on protein pathology and biomarkers

  • Studies across FTD subtypes (behavioral variant FTD, primary progressive aphasia, FTD-ALS, progressive supranuclear palsy, corticobasal syndrome)

    • Overview:
    The Pathways for Hope Pilot Grant is part of AFTD's long-standing Pilot Grant program, which has been operating for 20 years (since 2005). This grant provides seed funding to help early-career researchers and those exploring new ideas generate preliminary data and secure larger funding. The program has demonstrated strong success, with between 2005 and 2016 generating an estimated $7.53 million in follow-on federal funding from initial $955,000 in disbursements.

    Track Record:

  • Over 20 years, the program has funded $2.8 million in innovative FTD research

  • Recipients have gone on to secure NIH funding and other major grants

  • Grantees have launched successful clinical trials (e.g., Communication Bridge for PPA)

  • Many recipients maintain long-term relationships with AFTD and serve on review committees

    • 2025 Recipients:

  • Cyril Pottier, PhD (Washington University) - studying genetic factors influencing FTD onset and resilience in people with progranulin variants

  • Indira García Cordero, PhD (San Andres University, Argentina) - studying white matter changes in behavioral variant FTD across regions of Latin America and North America

    • Contact: AFTD HelpLine: 1-866-507-7222 or [email protected]

    Address: 2700 Horizon Drive, Suite 120, King of Prussia, PA 19406

    Focus Areas & Funding Uses

    Fields of Work

    science-research

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