CRISPRa Proof of Concept Constructs for MED13L Haploinsufficiency
Funding Amount
$165,000
Deadline
Deadline not published
Grant Type
Foundation
Deadline history & next window
- Cycle
- One-time opportunity
- Tracked since
- April 2026
Source: the cycle recorded on this listing. Confirm dates with the funder.
Overview
Project Duration: Two-year research period
Geographic Scope: United States (UCSF-based)
Focus Areas:
- CRISPR-based gene activation (CRISPRa) as a potential approach to increase MED13L gene expression
- Exploration of therapeutic strategies for MED13L Syndrome haploinsufficiency
- Foundational scientific knowledge advancement
- Therapeutic development landscape support
Research Institution
- Partner: University of California, San Francisco (UCSF)
- Agreement Type: Sponsored Research Agreement
Background
The MED13L Foundation is pursuing promising scientific avenues that may help families affected by MED13L Syndrome. This investment reflects the Foundation's commitment to accelerating research, strengthening the scientific pipeline, and improving long-term outcomes for individuals with MED13L Syndrome.
Contact Information
Address: 14 Main Street, Park Ridge, IL 60068
What The MED13L Foundation Inc actually gave
Source: IRS Form 990, 2024
- Grants in 2024
- 4
- Total given
- $292K
- Median grant
- $61K
- Range
- $4,781–$165K
- By dollars: California 56%, New Jersey 26%, Tennessee 17%. Top recipient cities: Palo Alto, CA; Glassboro, NJ; Nashville, TN.
Example grants
Transcripta Bio Inc (FKA Rarebase PBC) · Palo Alto, CA
Biomarker discovery project and drug discovery project using rarebase (now transcripta…
$165K
Rowan University Foundation Inc · Glassboro, NJ
Understanding of the role mitochondrial dysfunction plays in the pathoogy associated…
$77K
Vanderbilt University Medical Center · Nashville, TN
Exploring the impact of disease modifying compounds in med13l patient derive
$46K
Combined Brain · Brentwood, TN
Strategic research plan and biospecimen collection
$4,781
Focus Areas & Funding Uses
Fields of Work
- Science research
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