Abiomed Pre-Clinical Research Grants

Abiomed Pre-Clinical Research Grants support innovative studies that explore how Impella heart pumps can enhance patient outcomes. Funded by the Abiomed Charitable Foundation, these grants prioritize research in urgent patient care, heart recovery, and AI applications in cardiac interventions. Researchers are responsible for designing and managing their studies, with quarterly proposal reviews. This initiative aims to advance clinical knowledge and improve practices in heart recovery through rigorous scientific inquiry.

Abiomed funds research programs that investigate how mechanical circulatory support with Impella® heart pumps may improve patient outcomes.
Overview
Recovering hearts and saving lives is core to Abiomed’s mission. Our research grants program enables researchers to pioneer innovation in heart recovery. Through novel and groundbreaking research, the scientific community can provide critical insights and uncover solutions that translate to patient care. Abiomed funds innovative research proposals from qualified investigators to advance clinical knowledge and welcomes all research proposals related to heart recovery, with prioritization of our specific areas of interest.
Investigator Responsibilities & Expectations
Applicants awarded funding by Abiomed’s research grants program fulfill the role of the study sponsor and investigator. Abiomed fulfills the role of primary funding source. Funded sponsor-investigators are responsible for the design, management and conduct of the study, as well as maintaining compliance with all applicable laws and regulations. Abiomed and the sponsor-investigators will generate study-specific, progress-based milestones to align expectations and ensure timely execution of the study.
Abiomed funds research programs that investigate how mechanical circulatory support with Impella® heart pumps may improve patient outcomes.
All types of research programs will be considered, including but not limited to: clinical studies and pre-clinical investigations. All research programs must focus on how Impella support can improve patient outcomes. Research proposals are reviewed quarterly by Abiomed's academic research department. The deadline for submission to each of these quarterly review sessions is outlined below.
Areas of Interest
The following research domains have been identified by Abiomed to be areas of interest for innovation within the field.
Best Practices in Urgent and Emergent Patient Populations
Maximizing procedural, acute and long-term benefits while minimizing complication risks (ie. peripheral vascular complications and acute limb ischemia) for patients supported during urgent cases, including but not limited to: NSTEMI, CTO, peripartum cardiomyopathy and ECPR.
Exploring methods to guide how Impella can minimize time to treatment and escalation in critical cardiac situations for improved patient outcomes.
Exploring alternatives to heparin and A/C monitoring, including PPT and Anti-Xa guidance.
Impella Support for Heart Recovery
Use of Impella 5.5® with SmartAssist® for reverse remodeling and recovery, including mechanisms of action, adjunctive therapies, right heart failure, outcomes, best practices for patient management and prediction of patient recoverability.
Determining optimal duration of Impella support and weaning in Acute Myocardial Infarction with Cardiogenic Shock (AMI-CGS) and implications on both short-term and long-term patient recovery.
Utilizing artificial intelligence to predict recovery and enhance decision-making processes in Impella-supported cases, focusing on AI Digitization to improve the prediction of patient outcomes.
Impella as a Platform to Enable Cardiac Interventions in High-Risk Populations
Use of Impella in surgical and interventional procedures for pre-procedure optimization, BTT, BTR, or prevention of PCCS, including patient identification, timing of support, patient management.
End Organ Protection with Impella
Identification of patients at risk for cardiorenal or other end organ dysfunction and unmasking the mechanisms of organ-to-heart crosstalk.
Impact of Impella support on acute or chronic end organ dysfunction to improve patient outcomes.

Eligibility

Instructions for Grant Submission:

• Instructions for Grant Submission:
• All types of research programs will be considered, including, but not limited to:pre-clinical investigations
• Research programs must focus on how Impella support may improve patient outcomes.
• Research proposals are reviewed quarterly.
• Specific areas of interest, instructions for grant submission, and quarterly submission deadlines are outlined below.