Abiomed Clinical Research Grants

Abiomed Clinical Research Grants

Status: ACTIVE
Funder: Abiomed Charitable Foundation Inc.
Last Updated: February 04, 2026

Summary

Abiomed Clinical Research Grants aim to enhance patient outcomes through innovative research on mechanical circulatory support with Impella® heart pumps. The program supports diverse clinical studies, prioritizing proposals in areas such as urgent patient care, heart recovery, and AI applications in treatment decision-making. Researchers are expected to align with Abiomed's standards and funding priorities while contributing to advancements in cardiac health. Competitive reviews ensure high-quality research is funded, fostering breakthroughs that can save lives.

Overview

Note: The Concept submission deadlines are represented by the pre-proposal deadlines. Research Grants Abiomed funds research programs that investigate how mechanical circulatory support with Impella® heart pumps may improve patient outcomes. Overview Recovering hearts and saving lives is core to Abiomed’s mission. Our research grants program enables researchers to pioneer innovation in heart recovery. Through novel and groundbreaking research, the scientific community can provide critical insights and uncover solutions that translate to patient care. Abiomed funds innovative research proposals from qualified investigators to advance clinical knowledge and welcomes all research proposals related to heart recovery, with prioritization of our specific areas of interest. Investigator Responsibilities & Expectations Applicants awarded funding by Abiomed’s research grants program fulfill the role of the study sponsor and investigator. Abiomed fulfills the role of primary funding source. Funded sponsor-investigators are responsible for the design, management and conduct of the study, as well as maintaining compliance with all applicable laws and regulations. Abiomed and the sponsor-investigators will generate study-specific, progress-based milestones to align expectations and ensure timely execution of the study. Clinical Research Grants All types of research programs will be considered for funding through Abiomed’s Investigator-Sponsored Studies (ISS) office. ISS are clinical studies that are initiated, developed, and conducted by a qualified researcher external to Abiomed who assumes all legal and regulatory responsibility for the trial. Potential ISS programs are funded through a competitive review process. Areas of Interest The following research domains have been identified by Abiomed to be areas of interest for innovation within the field. Best Practices in Urgent and Emergent Patient Populations Maximizing procedural, acute and long-term benefits while minimizing complication risks (ie. peripheral vascular complications and acute limb ischemia) for patients supported during urgent cases, including but not limited to: NSTEMI, CTO, peripartum cardiomyopathy and ECPR. Exploring methods to guide how Impella can minimize time to treatment and escalation in critical cardiac situations for improved patient outcomes. Exploring Alternatives to Heparin and A/C monitoring, including PPT and Anti-Xa guidance. Impella Support for Heart Recovery Use of Impella 5.5® with SmartAssist® for reverse remodeling and recovery, including mechanisms of action, adjunctive therapies, right heart failure, outcomes, best practices for patient management and prediction of patient recoverability. Determining optimal duration of Impella support and weaning in Acute Myocardial Infarction with Cardiogenic Shock (AMI-CGS) and implications on both short-term and long-term patient recovery. Utilizing artificial intelligence to predict recovery and enhance decision-making processes in Impella-supported cases, focusing on AI Digitization to improve the prediction of patient outcomes. Impella as a Platform to Enable Cardiac Interventions in High-Risk Populations Use of Impella in surgical and interventional procedures for pre-procedure optimization, BTT, BTR, or prevention of PCCS, including patient identification, timing of support, patient management. End Organ Protection with Impella Identification of patients at risk for cardiorenal or other end organ dysfunction and unmasking the mechanisms of organ-to-heart crosstalk. Impact of Impella support on acute or chronic end organ dysfunction to improve patient outcomes.

Eligibility

You can learn more about this opportunity by visiting the funder's website. Researchers interested in applying to Abiomed for competitive research funding should familiarize themselves with investigator expectations, Abiomed funding priorities, and the research grant review process. Instructions for Grant Submission: All types of research programs will be considered, including, but not limited to: clinical studiesResearch programs must focus on how Impella support may improve patient outcomes. Research proposals are reviewed quarterly. Specific areas of interest, instructions for grant submission, and quarterly submission deadlines.Competitive Review Process Abiomed carefully evaluates all submitted proposals. The investigator-sponsored studies review board evaluates applications based on the following criteria: Scientific and clinical impact Alignment with established funding priorities Innovation Study design and methodology Investigator experience & research site infrastructure Feasibility Patient safetyAbiomed and investigators funded through the ISS office share a common goal of generating high-quality data, protecting human subjects, complying with all regulatory requirements, and advancing science for human health.Investigator-Sponsored Studies ResponsibilitiesStudy design & research protocol developmentSubmission of Investigational Device Exemption (IDE) application (if required)Study implementation & oversight Participant inclusion Obtaining proper informed consent Compliance with protocolRegulatory Submissions & Compliance IRB/EC approvals FDA submissions Protocol amendment submissions Continuing reviews Final study reports Safety reportingRegister study in a public database (e.g. clinicaltrials.gov)Contract with third-party vendorsDatabase development & data analysis PublicationsAbiomed ResponsibilitiesEvaluates the proposed study for funding based on scientific merit and business alignmentDistributes updated, approved product information Provides research grant award Monitors trial progress in accordance with agreed-upon milestones and protocolReviews protocol amendments Reviews study manuscripts prior to publication