What you must do
Failure to comply with the U.S. Constitution, federal statutes, regulations, or award terms exposes the recipient/subrecipient to escalating remedies: § 200.208 specific conditions first; then temporary payment withholding, cost disallowance, suspension or termination of the award, suspension/debarment proceedings under 2 CFR part 180 (or PTE referral for them), withholding of further federal funds (new awards or continuation funding), and other legally available remedies.
When it applies
Recipient or subrecipient fails to comply with the U.S. Constitution, federal statutes, regulations, or the terms and conditions of the Federal award