Upstream USA Inc logo

Upstream USA Inc

BOSTON, MA EIN: 35-2581424 Website

Upstream USA Inc is a 501(c)(3) nonprofit organization based in Boston, Massachusetts, focused on expanding access to patient-centered contraceptive care across the United States. The organization works in partnership with healthcare providers, including hospital systems, state and local health departments, Federally Qualified Health Centers (FQHCs), Planned Parenthoods, and community agencies, to strengthen reproductive care and increase equitable access to the full range of contraceptive options.

Financial Overview

From 2024 IRS Form 990-PF · View filing

Total Assets

$242.4M

-3.4% YoY

Annual Giving

$3.0M

+17.6% YoY

Grant Count

77

+10.0% YoY

Avg Grant Size

$39K

+6.9% YoY

Research compiled by Grantable AI from public sources. Last updated April 2026.

Mission & Focus Areas

Mission: Upstream's mission is to ensure that patient-centered contraceptive care is basic healthcare.

The organization addresses the gap in contraceptive care access in the United States, where an estimated 19 million women lack reasonable access to high-quality contraceptive care. Research cited by the organization indicates that 70% of women reported they would have preferred receiving additional information prior to making a contraceptive decision, and 45% of adults reported barriers to receiving reproductive healthcare, including 28% reporting access-related barriers.

Upstream provides comprehensive, evidence-based training and technical assistance to healthcare organizations. As of 2023, the organization had added 58 new partnerships serving 310,000 patients of reproductive age, with projections to deliver interventions to healthcare organizations serving 1.2 million patients of reproductive age by mid-2026.

Grantmaking

Upstream USA makes grants to support contraceptive coverage and related initiatives. Recent grants documented include:

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Geographic Focus

Where this funder awards grants

Upstream's work spans multiple states across the United States. The organization has expanded its reach through partnerships in states including Delaware, Rhode Island, North Carolina, Massachusetts, Colorado, and Texas.

Grant Distribution by State

27states
+19 more states

Cities

AlamosasAshervilleAshevilleAustinAvondaleBaton RougeBeaumontBellinghamBooneBostonBrightonBrownfieldBrownwoodCharlotteChehalisChicagoColorado SpringsCommerce CityConroeCoupeville

Financial History

Multi-year comparison from IRS filings

2023 Financial Data:

  • Total revenues: $121,746,531
  • Total expenses: $45,445,245
  • Total assets: $250,903,262
  • Number of employees: 206

2022 Financial Data:

  • Revenue: $80,222,610
  • Expenses: $29,801,749
  • Assets: $172,642,723

Organization Status:

  • EIN: 35-2581424
  • Tax-exempt since: May 2017
  • Founded: 2014
  • IRS ruling year: 2017
Revenue
Expenses
Qualifying Distributions
Net Investment Income
$0$33M$67M$100M$134M201920202021202220232024
Metric202420232022
Total Assets$242,356,291$250,903,262$172,642,723
Revenue$38,703,079$121,746,531$80,222,610
Expenses$47,863,156$45,445,245$29,801,749
Qualifying Distributions
Net Investment Income$9,611,750$6,695,562$1,245,738
Distributable Amount

Giving Over Time

Total grant dollars and number of grants per year

$0$760K$2M$2M$3M12 grants201914 grants202018 grants202122 grants202270 grants202377 grants2024

Grant Insights

How this funder distributes its grants

Top Recipients

Top 10 recipients in 2024

Womens Health and Family…$800KAllianceChicago - Illino…$204KMassachusetts League of …$150KWashington Association f…$100K504HealthNet Inc$100KCaring for Colorado Cent…$75KUnity Healthcare Inc$75KCodman Square Health Cen…$50KCharles River Community …$50KCommunity Health Center …$50K

Grant Size Distribution

154 grants across all recorded years

130<$50K13$50–100K8$100–250K1$250–500K2$500K–1M$1–5M$5M+

Giving History

Grant recipients and amounts by year

No grants recorded for .

Leadership & Key People

Leadership team and compensation from IRS filings

Mark Edwards serves as CEO and Co-Founder of Upstream USA Inc.

Compensation Overview

From 2024 IRS filing

Mark EdwardsCo-Founder$495KNicole MckinneyChief of Organizational Effe…$330KJessica GreenfieldCFO and Treasurer$328KLisa GoldthwaiteClinical Advisor$292KElizabeth KaltmanLead Clinical Advisor$274KSarah PiersonChief Dev and External Affai…$274KJessica BeamanLead Clinical Trainer$266KKeshia HughstonVP People and Culture$264KJessica FosterPresident from 12-05-2024$225KJohn HoAssistant Secretary$143K

From 2024 filing

NameTitleHoursCompensation
Mark EdwardsCo-Founder40$494,861
Nicole MckinneyChief of Organizational Effectiveness and Culture40$329,966
Jessica GreenfieldCFO and Treasurer40$327,712
Lisa GoldthwaiteClinical Advisor32$292,332
Elizabeth KaltmanLead Clinical Advisor24$274,008
Sarah PiersonChief Dev and External Affairs Officer40$273,864
Jessica BeamanLead Clinical Trainer32$266,162
Keshia HughstonVP People and Culture40$263,546
Jessica FosterPresident from 12-05-202440$224,936
John HoAssistant Secretary40$143,238
Anita BekensteinChair to 12-05-2024 and Comp Comm Chair1
Sarah BrownVice-Chair to 12-05-241
Keith HigginsSecretary and Nominating Gov Comm Chair1
Mark PerryChair from 12-05-24 and Prog Comm Chair1
Paul GannonFinance Committee Chair1
Howard StevensonAudit Committee Chair1
Lauren Schadt BakerBoard Member1
Thea JamesBoard Member1
Scott RansomBoard Member1
Donella RapierBoard Member1
Ann StarrsBoard Member1
Krishna WhiteBoard Member1

Recent Activity

Recent developments and announcements

2021

In 2021, Upstream forged three new partnerships with health centers in Rhode Island and North Carolina, extending their reach to more women of reproductive age. A Centers for Disease Control and Prevention report on Upstream USA's statewide initiative in Delaware found a 25 percent drop in the share of births from unwanted pregnancies, from 35.5 percent in 2014 to 27 percent in 2017.

Upstream Launches Bold Initiative to Eliminate Single-use Waste with Grant

Subject Areas

Focus areas based on grantmaking activity

Related Funders

Similar funders by location and focus area

Data last updated April 2026. Sourced from IRS Form 990-PF filings. Research dossier generated April 2026.

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