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The Greater Cincinnati Foundation

Cincinnati, OH

The Greater Cincinnati Foundation supports education, affordable housing, arts and culture, community well-being, neighborhood development, and basic needs, with responsive grants focused on its eight-county Greater Cincinnati service area. Its 2024 grants had a median of $20,000, while specific opportunities range from small awards to grants of up to $450,000. It offers open RFP and LOI opportunities; the profile does not state whether it accepts unsolicited requests outside those opportunities.

Selling to Give Foundation Inc

Raleigh, NC

Lilly Endowment Inc

Indianapolis, IN

Lilly Endowment funds community development, education and youth, and religion, with a national reach—especially in religion—and a particular commitment to Indianapolis and Indiana. Its 2025 grants had a median of $100,000, though awards ranged widely; the profile does not state whether it accepts unsolicited requests.

Ludwig Family Foundation

Brighton, MI

The Ludwig Family Foundation supports Christian teaching, evangelism, theological education, and church- and mission-related work, with recent grants concentrated in North Carolina and Michigan and others in several states. Its 2025 grants ranged from $5,000 to $50,000, with a median of $10,000. It funds only preselected charitable organizations and does not accept unsolicited requests.

Museum of the Bible

Oklahoma City, OK

The Museum of the Bible is an innovative, global, and educational institution whose purpose is to invite all people to engage with the transformative power of the bible. We do so through 4 main initiatives: our permanent museum in washington, d.c., traveling exhibitions, education and research. These are further described at www.museumofthebible.org/our-history.

Duke Energy Foundation

Charlotte, NC

The Duke Energy Foundation funds workforce development, local economic development and recovery, disaster resilience, conservation, and economic opportunity in communities across North Carolina, South Carolina, Florida, Ohio, Kentucky, and Indiana. It reports more than $30 million in annual charitable grants; awards vary widely, with a 2024 median of $25,000, and applications of $20,000 or less are accepted on a rolling basis. Applicants should contact their local Foundation representative before applying.

Brady Family Foundation

Cary, NC

Enterprise Holdings Foundation

Saint Louis, MO

Enterprise Holdings Foundation supports nonprofits in health, education, arts, disaster relief, reforestation, hunger relief, and community equity, with an emphasis on organizations actively supported by Enterprise employees and their families. Its reported grants range widely: 2024 giving averaged about $7,700 across 9,499 grants, while the foundation also offers awards of up to $40,000; it supports communities where Enterprise operates worldwide. Unsolicited requests are accepted at any time, but eligible applications must be submitted by an Enterprise team member or their spouse or domestic partner on behalf of a nonprofit they actively support.

Greater Horizons

Kansas City, MO

Greater Horizons is a donor-advised fund provider whose donor-directed grants support eligible U.S. public charities across a broad range of causes; international organizations may also qualify with additional review and fees. In 2024, grants had a median of $15,000, with itemized awards ranging from $5,001 to $10,073,050, and recipients were located across the United States, especially in California, Texas, Nebraska, New York, and Kansas. It describes a grant-request process for donors, not an application process for organizations, so unsolicited requests are not stated as accepted.

St Louis Community Foundation Inc

St. Louis, MO

The St. Louis Community Foundation supports nonprofits through donor- and foundation-directed grants, with priorities including economic mobility and youth connections as well as education, health, arts, and culture. Its 2024 grants had a median of $20,000, though amounts ranged from $5,050 to $4 million; its regional priorities center on Greater St. Louis, especially designated high-need ZIP codes. Grant processes vary by fund, so the profile does not establish whether the Foundation accepts unsolicited requests generally.

Commerce Bancshares Foundation

Kansas City, MO

The foundation supports a broad range of charitable organizations and community projects, with 2024 grants typically small (median $1,500) but ranging from $200 to $60,500. Most funding went to Missouri, followed by Kansas and Illinois, with smaller amounts elsewhere; it says applicants should contact the program director and provide proof of 501(c)(3) status, and does not restrict giving to preselected organizations.

Patterson Family Foundation

Kansas City, MO

The Patterson Family Foundation funds healthcare, education, and economic opportunity, including program, operating, equipment, and capital grants for organizations serving rural communities in Kansas and western Missouri, generally in counties under 50,000 residents. Its 2021 awards ranged from $144 to $2.5 million, with a median of $6,300; it says it does not accept unsolicited funding requests and contributes only to preselected charitable organizations.