The G Harold & Leila Y Mathers
The G. Harold & Leila Y. Mathers Charitable Foundation is a private, permanently endowed charitable organization established in 1983 in Santa Barbara, California. Based in Rye Brook, New York, the foundation is dedicated to advancing knowledge in the life sciences by funding bold, basic scientific research with the potential to transform human health. The foundation was created to honor the philanthropic vision of G. Harold Mathers (1901–1976) and Leila Young Mathers (1905–1980), with initial funding derived from assets of the C. W. Post estate.
Financial Overview
From 2024 IRS Form 990-PF · View filing
Total Assets
$107.9M
+8.0% YoY
Annual Giving
$17.3M
+4.9% YoY
Grant Count
103
+35.5% YoY
Avg Grant Size
$168K
-22.6% YoY
Mission & Focus Areas
The foundation is primarily interested in supporting fundamental basic research in the life sciences. Support is provided for specific projects from established researchers at top universities and independent research institutions within the United States. The foundation has evolved from focusing solely on basic medical research to embracing innovative research with translational potential.
Since its inception, the foundation has granted more than $350 million to support research aimed at advancing knowledge in the life sciences.
Grantmaking
The foundation operates a single grant program with the following characteristics:
Grant Range
$600,000 - $700,000 over three years, inclusive of 10% indirect costs
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Geographic Focus
Where this funder awards grants
The foundation funds U.S.-based 501(c)(3) institutions. Primary geographic areas of grantmaking include Massachusetts, New York, and California.
Grant Distribution by State
States
Cities
Financial History
Multi-year comparison from IRS filings
As of 2023:
- Total assets: $99,932,556
- Total revenues: $23,491,261
- Total expenses: $16,295,854
- Staff: 6 employees
As of 2024:
- Total assets: $107,899,647
- Annual giving: $18.6 million
| Metric | 2024 | 2023 | 2022 |
|---|---|---|---|
| Total Assets | $107,899,647 | $99,932,556 | $96,422,457 |
| Revenue | $29,243,446 | $23,491,261 | $20,904,966 |
| Expenses | $18,497,648 | $16,295,854 | $23,366,307 |
| Qualifying Distributions | $18,623,245 | $17,624,210 | $18,303,915 |
| Net Investment Income | $26,786,487 | $21,255,933 | $18,749,568 |
| Distributable Amount | $19,360,324 | $16,887,562 | $17,183,059 |
Giving Over Time
Total grant dollars and number of grants per year
Grant Insights
How this funder distributes its grants
Top Recipients
Top 10 recipients in 2024
Grant Size Distribution
250 grants across all recorded years
Open Grants
1 open opportunity from The G Harold & Leila Y Mathers
Giving History
Grant recipients and amounts by year
No grants recorded for .
Leadership & Key People
Leadership team and compensation from IRS filings
Zachary Handelman serves as Treasurer, Vice President, and Director of the foundation.
Compensation Overview
From 2024 IRS filing
From 2024 filing
| Name | Title | Hours | Compensation |
|---|---|---|---|
| DAVID BOYLE | DIRECTOR | 2 | $50,000 |
| RICHARD HANDELMAN | PRES/DIR | 4 | $50,000 |
| JUDY HERMAN | DIRECTOR | 2 | $50,000 |
| PETER GOTTLIEB | DIRECTOR | 2 | $45,000 |
| HOWARD CHESTER | SECRETARY/DIRECTOR | 40 | $500,000 |
| ZACHARY HANDELMAN | TREASURER/VP/DIR OF OPERATIONS | 30 | $210,000 |
| SCOTT HANDELMAN | DIRECTOR | 2 | $10,000 |
Contact Information
Address: 800 Westchester Avenue, Suite N-503, Rye Brook, New York 10573
Email: grants@mathersfoundation.org
Website: https://mathersfoundation.org/
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Data last updated April 2026. Sourced from IRS Form 990-PF filings. Research dossier generated April 2026.
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