Marion G Resch Foundation

Orris C&B Dewey Hirtzel Memorial FD

Pittsburgh, PA

The foundation funds scholarships, health care and medical research, and community services such as parks, libraries, public schools, and volunteer fire companies. In 2024, grants ranged from $2,500 to $320,000, with a median award of $7,500; its primary area is Erie County, Pennsylvania, and Chautauqua County, New York, with some medical and research support across Western Pennsylvania, Western New York, and Northern Ohio. Application details are provided after initial contact, but the profile does not state whether unsolicited requests are accepted.

The Wm M & a Cafaro Family Foundation

Niles, OH

The foundation supports a broad range of charitable causes, including education, churches, health and community organizations, with scholarships for students in eastern Ohio. Its 2026 grants ranged from $50 to $300,000, with a median of $500, and most funding went to Ohio recipients. Its filing says it does not limit giving to preselected organizations and describes how to submit a request.

Wright R R Educational FD - UA

Pittsburgh, PA

Gladys M Hess Memorial Scholarship Fund

Russellton, PA

Buhl Regional Health Foundation

Hermitage, PA

Buhl Regional Health Foundation funds nonprofit health and well-being efforts in Mercer County, with a current priority on children and youth; eligible mini-grants support youth health and access to care. Giving varies widely: 2024 awards ranged from $200 to $1.5 million, with a median of $6,180, and mini-grants are capped at $5,000. It accepts applications through rolling mini-grants and selected RFPs; mini-grants are submitted through its portal.

Otto Ruth Varner-Seneca Valley High

Pittsburgh, PA

The Pearce Foundation

Columbus, OH

Powers E & a Higher Educ FD

Pittsburgh, PA

The Business of Good Foundation

Ashtabula, OH

The Business of Good Foundation supports nonprofit leaders and social entrepreneurs working to empower economically disadvantaged people, and its grants have backed education, mentoring, basic needs, housing, and youth programs. In 2025, grants ranged from $1,000 to $595,000, with a median of $5,000; most funding went to Ohio, especially Northeast Ohio. Its 2024 filing says it accepts written requests with proof of exempt status and a proposed use of funds.

Columbus Foundation

Columbus, OH

The Columbus Foundation supports nonprofits and community initiatives in areas including arts and culture, education, youth, neighborhoods, basic needs, and capacity building, with a median 2024 grant of about $21,500. Its focus is Central Ohio, though it also funds organizations elsewhere; most grants are donor-directed and not application-based, but some programs accept applications.

The Greater Cincinnati Foundation

Cincinnati, OH

The Greater Cincinnati Foundation supports education, affordable housing, arts and culture, community well-being, neighborhood development, and basic needs, with responsive grants focused on its eight-county Greater Cincinnati service area. Its 2024 grants had a median of $20,000, while specific opportunities range from small awards to grants of up to $450,000. It offers open RFP and LOI opportunities; the profile does not state whether it accepts unsolicited requests outside those opportunities.

The Cleveland Foundation

Cleveland, OH

The Cleveland Foundation funds nonprofits working on community needs and long-term priorities, including education, health, arts and culture, economic development, neighborhoods, and human services in Cuyahoga, Lake, and Geauga counties. Its 2024 grants had a median of about $30,700, though amounts varied widely. Its general application is open year-round, so it accepts unsolicited requests through that process.