JS Greene Memorial Foundation

Houston Texans Foundation

Houston, TX

The Houston Texans Foundation supports youth and families through education, youth development, health and wellness, economic advancement, community resources, and social justice, with a focus on Houston and Harris County and neighborhood efforts in Greenspoint, Magnolia Park, and Sunnyside. In 2024, grants ranged from $5,871 to $250,000, with a median of $20,000. Unsolicited grant applications are not addressed; Texas-based nonprofits may submit online requests for in-kind donations.

The Buum Foundation

Houston, TX

ESB3 Foundation

Houston, TX

ESB3 Foundation supports charitable organizations across areas including culture, health, disability services, community needs, and education, with 2024 grants going to recipients in Texas and Pennsylvania. Its 12 grants ranged from $5,000 to $1.35 million, with a median of $50,000; it does not accept unsolicited requests and gives only to preselected organizations.

The Ott Family Foundation

Houston, TX

AbbVie Foundation

North Chicago, IL

The AbbVie Foundation funds health equity, access to care, cancer care, and community-led health solutions through partnerships and local programs, supporting communities worldwide. Its 2025 grants ranged from $8,000 to $15 million, with a median of $25,000. It says it funds only preselected organizations and does not accept unsolicited requests; a separate Health Equity Accelerator is listed as encouraging applications, but its application details are not specified.

McKesson Foundation Inc

Dallas, TX

McKesson Foundation supports healthcare access across the U.S. and Canada, focusing on cancer, healthcare workforce training, and emergency response, especially for vulnerable communities; local priorities include Atlanta, Columbus, Dallas-Fort Worth, Houston, Memphis, Montreal, Richmond, and Toronto. Its 2025 grants ranged from $10,000 to $2.47 million, with a median of $100,000. Its filing says it does not accept unsolicited requests, while its current website describes online applications: up to $25,000 year-round and larger requests from February 1 through April 30.

Melbern G & Susanne M Glasscock

Houston, TX

This Houston-based foundation supports a range of cultural, educational, health care, and human-service organizations, with nearly all 2024 grant dollars going to Texas recipients. Its 2024 grants ranged from $15,000 to $300,000, with a median of $32,500. It accepts applications anytime and directs applicants to contact the foundation for guidelines.

Harris County Hospital District

Bellaire, TX

It funds Harris Health System and related patient-care and community health work, including children’s health, heart health, cancer resources, trauma outreach, and employee support, primarily in Harris County, Texas. In 2025, grants ranged from $10,000 to $2.63 million, with a median of $24,411; it has application processes for its Children’s Health Fund and small grants, but whether it accepts unsolicited requests is not stated.

Rockwell Fund Inc

Houston, TX

Rockwell Fund supports Greater Houston nonprofits working on community development, including housing, food access, health, education, flood resilience, and nonprofit capacity, with current priority given to organizations serving or benefiting Houston’s Super Neighborhood 52. Its 2024 grants ranged from $2,500 to $235,000, with a median of $67,500. It accepts unsolicited requests through an open application process, though some opportunities are invitation-only.

MD Anderson Foundation

Houston, TX

The MD Anderson Foundation funds tax-exempt organizations working in health and medicine, education, arts and culture, and improving the lives of underserved people, primarily in Houston and Harris County, Texas. In 2024, grants ranged from $7,500 to $360,000, with a median of $50,000. It accepts written applications from tax-exempt organizations; no deadline is stated.

The Brown Foundation Inc

Houston, TX

The Brown Foundation funds education, arts and culture, healthcare, human services, and civic assets, with education and the arts as top priorities and public education giving focused almost exclusively on greater Houston. Its 2025 grants ranged from $20,000 to $11 million, with a median of $50,000; it primarily supports Houston organizations and selectively funds distinctive opportunities elsewhere in Texas and beyond.

Houston Endowment Inc

Houston, TX

Houston Endowment funds public education, civic engagement, arts and culture, and greenspaces, supporting work that benefits people in Greater Houston, including Harris County and its contiguous counties. Its 2024 grants ranged from $500 to $5 million, with a median of $125,000. Grants are by invitation only; it does not accept unsolicited requests.