DYRK1A Syndrome US

The Terra Foundation

Scottsdale, AZ

Childs Cure Genetic Research Non Profit Corporation

Reno, NV

Sponsor and manage pre-clinical research and drug discovery programs, Raise awarness about genetic disorders affecting children, lead and sponsor the research and treatments to help children in need. Assist with fiscal sponsorship and fundraising framework to help parents.

Cure KCNH1 Foundation

Encinitas, CA

Our mission is to urgently improve the lives of individuals and families affected by KCNH1-Related Disorders by accelerating research toward the development of effective treatments and a cure building connections within the KCNH1 patient and professional community raising awareness about KCNH1-related disorders and advocating for the needs of families affected by rare diseases.

Lydian Accelerator

San Francisco, CA

To invest in scientific and translational research of personalized genetic treatments for children impacted by severe genetic disease.

The Wolverine Foundation

Greenwich, CT

The Wolverine Foundation’s website describes research grants benefiting wolverines or their habitat, typically $5,000–$10,000, while its 2024 grants also supported medical research, education, and charitable services, mainly in California, Connecticut, New York, Alabama, and Massachusetts. The website says it is not currently offering research grants and does not accept unsolicited requests, making contributions only to preselected organizations.

Target ALS Foundation Inc

New York, NY

Target ALS funds collaborative research and drug discovery focused on ALS, including disease biology, biomarkers, and therapeutic targets. Its 2025 grants ranged from about $49,000 to $800,000, with a median of about $129,000; opportunities are open to investigators worldwide. It says it does not accept unsolicited requests and makes contributions only to preselected charitable organizations.

Elster Foundation AGT

Atlanta, GA

ELSTER FOUNDATION AGT funds organizations in the arts, education, community support, and conservation, with 2025 grants going to recipients in multiple states, especially Georgia, Florida, and Virginia. Grants ranged from $500 to $60,000, with a median of $3,000. It does not accept unsolicited requests and gives only to preselected organizations.

The Conrad Prebys Foundation

San Diego, CA

The Conrad Prebys Foundation funds visual and performing arts, youth success, healthcare, and medical research, primarily in San Diego County. Its 2024 grants ranged from $200 to $3 million, with a median of $100,000. It offers opportunities throughout the year, including open applications and requests for proposals, but may also use invitation-only or community-led processes.

The Trustees of Columbia University in the City of New York

New York, NY

Columbia funds research, education and research, and capital projects, primarily through grants to universities and medical and research institutions across the United States, with the largest share going to New York recipients. Its 2025 grants had a median of about $109,000, though awards ranged from $5,350 to $15.1 million. The profile does not state whether it accepts unsolicited requests.

The San Diego Foundation

San Diego, CA

The San Diego Foundation funds nonprofit work in family well-being, education, the environment, and housing, including projects, capacity building, and general support that advance equity and resilient communities. Its 2025 grants had a median of $25,000, though amounts varied widely; applicants generally must be located in San Diego County and primarily serve county residents. It offers competitive grant opportunities through its online portal, but the profile does not state whether it accepts unsolicited requests.

Silicon Valley Community Foundation

Mountain View, CA

Silicon Valley Community Foundation funds work in areas such as housing, economic security, education, health, the environment, arts and culture, and civic engagement, with Community Action Grants supporting local, community-led organizations in San Mateo and Santa Clara counties. Its 2024 grants had a median of $51,716, though amounts varied widely; applications depend on the program, and SVCF states that it does not accept unsolicited proposals for advised funds.

The Chicago Community Trust

Chicago, IL

The Chicago Community Trust funds eligible nonprofits working to narrow the wealth gap and meet urgent needs, with priorities including economic mobility, education, jobs, homeownership, and community development in metropolitan Chicago and Cook County. Its 2025 grants had a median of $26,500, though amounts varied widely; the profile does not state whether it accepts unsolicited requests.