Path to a Cure (PTAC) – Pioneer Award Grant

Path to a Cure (PTAC) – Pioneer Award Grant

Status: ACTIVE
Funder: Cystic Fibrosis Foundation
Last Updated: July 09, 2025

Summary

The Cystic Fibrosis Foundation's Path to a Cure (PTAC) – Pioneer Award aims to support groundbreaking research that could lead to a cure for cystic fibrosis at a cellular or genetic level. This award encourages ambitious proposals utilizing innovative techniques, with no prior CF research experience required. Collaborative efforts are encouraged to enhance the project's focus. Applicants can request funding that exceeds typical grants, including an option for indirect costs.

Overview

Note: LOI Submission Deadline - Rolling/closes on December 5, 2025; LOI Notification and Discussion: 2-4 weeks after receipt; Full Application Deadline: As agreed upon/closes on December 5, 2025 About the Cystic Fibrosis Foundation The mission of the Cystic Fibrosis Foundation is to cure cystic fibrosis and to provide all people with CF the opportunity to lead long, fulfilling lives by funding research and drug development, partnering with the CF community, and advancing high-quality, specialized care. To achieve this mission, various types of grants and awards are offered to support meritorious research in CF. Path to a Cure (PTAC) – Pioneer Award Program and Award Overview The Pioneer Award is intended to support paradigm shifting technologies that have the potential to cure CF at the cellular and/or genetic level. Proposals should be ambitious and utilize cutting edge techniques and strategies. A history of CF research is not required. However, applicants new to CF are encouraged to collaborate or establish a dialogue with members of the CF research community. Proposals must align with the goals of the Path to a Cure initiative outlined in section VI. While not required, a multidisciplinary team of investigators are encouraged to jointly apply as a collaboration if the project maintains a single primary focus. Funding Amounts Applicants should request a funding amount necessary to complete the proposed research project. It is anticipated that the scope of work and requested funding will exceed a CFF Research Grant or a typical NIH R01 award. An additional twelve percent (12%) indirect costs may be requested.

Eligibility

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