Novel Research Grants

The Lupus Research Alliance Novel Research Grants program is a proven platform for innovation that supports bold, pioneering research into lupus. The program has a 16+ year foundation of documented success in bringing new insights and untried directions to the complexities of lupus.

Program Focus:

• Encourages scientists to explore at the frontiers of current knowledge
• Tests new theories about what causes lupus and why it has such varied and widespread effects in the body
• Supports fundamental, translational, and clinical research approaches
• Explores diverse perspectives on lupus mechanisms and treatments

Geographic Scope: United States (institutions include Yale, University of Washington, Children's Hospital of Philadelphia, UC San Diego, Fred Hutchinson Cancer Research Center, Brigham and Women's Hospital, Medical University of South Carolina, Methodist Hospital Research Institute, University of Nebraska Medical Center, Hospital for Special Surgery, University of Pittsburgh, Monash University, UC San Francisco, and others)

Research Areas Funded:

• B cell dysfunction and autophagy
• Immune tolerance mechanisms
• Mitochondrial dysfunction and inflammation
• Regulatory T cell dysfunction
• Neuropsychiatric manifestations in pediatric lupus
• Drug repurposing for lupus treatment
• Ferroptosis in lupus nephritis
• Epigenetic regulation
• T cell exhaustion
• Lymphatic regulation and photosensitivity

Recent Awardees Examples:

• Erika Boesen, PhD (University of Nebraska Medical Center) - Ferroptosis as a Novel Driver of Inflammation in Lupus Nephritis
• Theresa Lu, PhD (Hospital for Special Surgery) - Lymphatic Regulation and Photosensitivity
• Kevin Nickerson, PhD (University of Pittsburgh) - Age-Associated B cells in Autoimmune Lupus
• Joshua Ooi, PhD (Monash University) - Genetically Engineering Regulatory T cells to Treat SLE
• Jeremy Tilstra, MD, PhD (University of Pittsburgh) - Examining the Role of T cell Exhaustion in Lupus Pathogenesis
• Michael Waterfield, MD, PhD (UC San Francisco) - Epigenetic Regulation of Il2 by ATF7ip — Implications for SLE

Application Process

Detailed application procedures and submission requirements are not provided in the available website content. Prospective applicants should visit the Lupus Research Alliance website or contact the organization directly.

Contact for More Information:

• Lupus Research Alliance
• 52 Vanderbilt Ave, Suite 401, New York, NY 10017
• 646-884-6000
• Website: lupusresearch.org