NFRP Outreach and Invitation for Response

The Congressionally Directed Medical Research Program (CDMRP) Neurofibromatosis Research Program (NFRP) and the US Army Medical Research Acquisition Activity (USAMRAA) are exploring the possibility of pursuing a Research-based Other Transactions Agreement (rOTA) in accordance with 10 U.S.C. 2371 to support a major goal/product-driven team of exceptional institutions and investigators that will accelerate the clinical translation of basic NF research and ultimately decrease the impact of the disease. The objectives of the resulting rOTA shall be to conceive, design, develop, and conduct collaborative Phase I and II clinical evaluations of promising therapeutic agents for the management or treatment of NF1, NF2, and schwannomatosis. Historically, this requirement has been competed as an assistance agreement, with prior awards made as part of the FY06, FY11, and FY16 portfolios. If the Government pursues this requirement as a rOTA, it is anticipated that this will be awarded as part of the FY21 portfolio. The Government is currently requesting feedback regarding the proposed approach and capabilities . All communication may be sent to Jason.D.Kuhns.civ@mail.mil . This Outreach and Invitation for Response is issued solely for information and planning purposes and does not constitute a solicitation. Neither unsolicited proposals nor any other kind of offers will be considered. Responses to this notice are not offers and will not be accepted by the Government to form a binding contract. Responders are solely responsible for all expenses associated with responding accordingly. General Information The Government anticipates an arrangement with a single Operations Center and a minimum of five Clinical Trial Sites with a demonstrated history of collaborative research. The participants will be jointly responsible for prioritizing, proposing, conducting, and analyzing Phase I and Phase II clinical trials focused on therapeutic interventions for NF1, NF2, and schwannomatosis. Th

Details

• Agency: Dept. of the Army -- USAMRAA
• Department: Department of Defense
• Opportunity #: W81XWH-21-NFRP-OUTREACH
• Instrument: other
• Cost Sharing: Required