DOD Defense Health Agency (DHA) Research & Development FY23-FY27 BROAD AGENCY ANNOUNCEMENT for Extramural Medical Research

The scope of this effort and the priorities attached to specific projects are influenced by changes in military and civilian medical science and technology (S&T), operational requirements, military threat assessments, and national defense strategies. Extramural research and development programs play a vital role in the fulfillment of the objectives established by the USAMRDC. General information on the USAMRDC can be obtained at https://mrdc.health.mil/. This BAA is intended to solicit extramural research and development ideas using the authority provided by 10 USC 4001. The BAA is issued under the provisions of the Competition in Contracting Act of 1984 (Public Law 98-369), as implemented in FAR 6.102(d)(2) and 35.016 and in Department of Defense Grant and Agreement Regulations (DoDGARs) 22.315. In accordance with FAR 35.016, projects funded under this BAA must be for basic and applied research to support scientific study and experimentation directed toward advancing the state-of-the-art or increasing knowledge or understanding rather than focusing on development of a specific system or hardware solution. Research and development funded through this BAA are intended and expected to benefit and inform both military and civilian medical practice and knowledge. This BAA utilizes competitive procedures in accordance with 10 USC 3012 for the selection for award of S&T proposals/applications. For the purposes of this BAA, S&T includes activities involving basic research, applied research, advanced technology development, and, under certain conditions, may include activities involving advanced component development and prototypes. The selection process is highly competitive, and the quantity of meaningful submissions (both pre-proposals/pre-applications and full proposals/applications) received typically exceeds the number of awards that available funding can support. This BAA provides a general description of USAMRDC’s research and development programs, including Research Areas of Interest, evaluation and selection criteria, pre-proposal/ pre-application and full proposal/application preparation instructions, and general administrative information. Specific submission information and additional administrative requirements can be found in the document titled, “General Submission Instructions,” which is available on Grants.gov along with this BAA. The FY23-FY27 USAMRDC BAA is continuously open for a 5-year period, from October 1, 2022 through September 30, 2027, at 11:59 p.m. Eastern Time. Submission of a pre-proposal/pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) (https://eBRAP.org/). Pre-proposals/pre-applications may be submitted at any time throughout the 5-year period. If the USAMRDC is interested in receiving a full proposal/application, the Principal Investigator will be sent an invitation to submit via eBRAP. A full proposal/application must be submitted through Grants.gov (http://www.grants.gov/). Invited full proposals/applications can be submitted under this FY23-FY27 BAA through September 30, 2027.

FY25 MRDC BAA HT942523SBAA1

I. OVERVIEW OF THE FUNDING OPPORTUNITY
Defense Health Agency Research & Development
BROAD AGENCY ANNOUNCEMENT
for Extramural Medical Research
Funding Opportunity Number: HT942523SBAA1
Announcement Type: Initial
Assistance Listing Number: 12.420
Military Medical Research and Development
KEY DATES
Release/Posted Date: October 1, 2022
Closing Date: September 30, 2027, 11:59 p.m. Eastern Time
This funding opportunity announcement is a broad agency announcement (BAA). It is
continuously open for a 5-year period, from October 1, 2022, through September 30, 2027,
11:59 p.m. Eastern Time.
This broad agency announcement must be read in conjunction with the General Submission
Instructions, which are available for downloading from Grants.gov. The General Submission
Instructions are located under the “package tab” and can be downloaded by selecting the
“Download Instructions” icon when previewing the submission package.
FY23 – FY27 DOD USAMRDC Broad Agency Announcement 1
for Extramural Medical Research

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Table of Contents
I. OVERVIEW OF THE FUNDING OPPORTUNITY ........................................................1
I.A. New for Fiscal Year 2023 – Fiscal Year 2027 ..................................................................5
II. DETAILED INFORMATION ABOUT THE FUNDING OPPORTUNITY ..................6
II.A. Program Descriptions ........................................................................................................7
II.A.1. Military Infectious Diseases ....................................................................................7
II.A.2. Combat Casualty Care .............................................................................................8
II.A.3. Traumatic Brain Injury ..........................................................................................11
II.A.4. Psychological Health .............................................................................................13
II.A.5. Sensory Systems ....................................................................................................14
II.A.6. Musculoskeletal Injury...........................................................................................15
II.A.7. Environmental Exposures ......................................................................................16
II.A.8. Directed Energy/Radiation Health .........................................................................17
II.A.9. DOD Working Dogs ..............................................................................................17
II.B. Award Information ..........................................................................................................18
II.B.1. Clinical Trial Support ............................................................................................19
II.B.2. Use of Military and Department of Veterans Affairs Populations or Resources ...19
II.B.3. Technology Requirements and Standards ..............................................................20
II.B.4.