NF1 Basic & Translational Laboratory Scholars Program Grant

NF1 Basic & Translational Laboratory Scholars Program Grant

Status: ACTIVE
Funder: Children's Tumor Foundation
Amount: Up to US $145,000
Last Updated: July 31, 2025

Summary

The NF1 Basic & Translational Laboratory Scholars Program, established by the Children's Tumor Foundation, aims to cultivate the next generation of NF1 researchers. This initiative supports early-career scientists by providing essential funding and mentorship, ensuring the continuity of research in NF1. With a focus on cutaneous neurofibromas and cognitive function, the program addresses the urgent need for innovative therapies and academic leadership in the NF community, following the cessation of federal funding for related research.

Overview

Background The Neurofibromatosis Therapeutic Acceleration Program (NTAP) was inspired by two parents whose daughter was diagnosed with NF1 in 2007. Shocked to learn that despite NF1 being one of the world’s most common rare diseases there were no medical answers or approved drug therapies, they set about to create an organization  -- The Children’s Tumor Foundation (CTF) -- that would focus on two of the most devastating symptoms of NF1: plexiform and cutaneous tumors. From their own experiences, they knew the importance of leadership programs and they were committed to establishing a program to train the next generation of clinician scientists in NF1. The foundation for NTAP was sealed when they met Dr. Jaishri Blakeley at Johns Hopkin University. Her creativity, drive and kindness were matched only by her desire to deliver therapeutic results. Together these parents, Dr. Blakeley, and a small group of trusted industry and academic advisors, established NTAP in 2012. It is this vision and collaboration that continues to inspire NTAP’s work each day. NF1 Basic & Translational Laboratory Scholars Program Program overview The Neurofibromatosis (NF) community has long benefited from the essential work of discovery and translational scientists. To help cultivate the next generation of leaders in NF1 research, NTAP at Johns Hopkins University has launched the NF1 Basic and Translational Laboratory Scholars Program—an initiative designed to support outstanding early-career scientists dedicated to advancing basic and translational research in NF1. This program was developed in direct response to the termination of funding for the CDMRP Neurofibromatosis Research Program in 2025 and the resulting pause in the NF Research Academy. While NTAP expects the program’s eventual federal reinstatement, this new initiative offers critical interim support to ensure the momentum of NF1 research continues uninterrupted—and that the field’s emerging leaders receive the mentorship and resources they need to thrive. Program Highlights Target Audience: Early-stage research faculty (PhD or equivalent) in their first professional appointment and establishing independent labs focusing on NF1. Support Includes: Laboratory salary support, research expenses, travel and education expenses and comprehensive mentorship. Collaborative Environment: Scholars will work closely with clinicians and scientific thought leaders in the field. Focus Areas: All NF1 topics welcomed, with special emphasis on cutaneous neurofibromas and cognitive function/development. Professional Development: Training in communication, grant writing, regulatory topics, team science, and community engagement. Program Goals Build a diverse community of NF1-focused scientistsAccelerate impactful NF1 basic and translational researchPrepare scholars for long-term leadership in academia, government, or industry research focused on NF1Position scholars for future funding success (e.g., R01, U01, foundation grants). This program complements the Children’s Tumor Foundation’s Young Investigator Award and represents a critical bridge to sustain momentum in NF1 science until long-term federal support resumes. The award will consist of: Up to $100,000 per year for laboratory personnel, inclusive of fringe benefits* Research supplies support: maximum of $30,000 per year Travel/Education/Program building: $5,000 per year Mentorship stipend: $10,000 per year Up to three years 10% IDC rate

Eligibility

We've imported the main document for this grant to give you an overview. You can learn more about this opportunity by visiting the funder's website. Hold a PhD (or equivalent doctoral degree) in a relevant scientific field. Be within 5 years of your first faculty (or faculty equivalent) appointment. Work at a non-profit research-focused institution, including federal and state research institutes. With appropriate justification, candidates at for-profit research entities will be considered. Demonstrate a track record of academic and research excellence. Show a strong commitment to NF1-focused research.Have a mentorship committee, including at least one lead mentor with expertise in NF1. Secure institutional support, including: Access to appropriate facilities and administrative resourcesMentorship infrastructure and commitment to oversightWillingness to comply with all of NTAP's funding requirements.