General Research Funding Program

The Pediatric Brain Tumor Foundation is the largest patient advocacy funder of pediatric brain tumor research and is wholly dedicated to ending the most commonly diagnosed and deadliest childhood cancer. The foundation supports research across multiple tumor types and research categories.

Geographic Scope: United States and international institutions

Supported Research Types:

• Basic and Translational Science
• Clinical Trials
• Core Scientific Resources and Infrastructure
• Survivorship Research
• Other innovative approaches

Supported Brain Tumor Types:

• Atypical Teratoid/Rhabdoid Tumors (AT/RT)
• Choroid Plexus Tumors
• Craniopharyngiomas
• Diffuse Intrinsic Pontine Gliomas (DIPG)
• Diffuse Midline Gliomas (DMG)
• Ependymomas
• Germ Cell Tumors
• High-grade Gliomas
• Low-grade Gliomas
• Medulloblastomas
• Pineoblastomas

Example Funded Projects (2024-2025):

• Establishing and Credentialing a PLGA Xenograft Collection - $375,000 over 3 years
• Characterizing Pediatric Brain Tumor Patient Derived Organoids (PDO) for Precision Drug Screening - $100,000
• Investigating Mechanisms of Recurrence after Immune Gene Therapy in G34-Mutant Pediatric High-Grade Glioma - $750,000 over 2 years
• BTFC 2 of 2: Global Alliance to Establish a CSF-based Liquid Biopsy Platform for Brain Tumors - $100,000
• BTFC 1 of 2: Maximizing Detection of Childhood Brain Tumors in Biofluids - $100,000
• SNO: Neuro-Oncology Pediatrics Journal (2024-2025) - $200,000 over 2 years
• Accelerating the Clinical Translation of Nanomedicines for Pediatric Brain Tumors (ECD) - $300,000 over 3 years
• Kindred - Elucidating the mechanisms of dissemination and therapy resistance in pediatric low-grade glioma - $650,000 over 3 years
• Advancing Pediatric Brain Tumor Research Through Crucial Infrastructure Support - $222,000

Application Process

The PBTF awards grants for research on an ongoing basis. Detailed step-by-step application procedures are not fully provided in the available website content.

To Apply:

1. Visit the "Apply for Funding" section at curethekids.org/research/apply-for-funding
2. Review specific grant opportunity guidelines
3. Contact PBTF directly for:
   • Application materials and requirements
   • Current funding priorities
   • Specific deadlines for different grant types
   • Budget guidelines
   • Required documentation

Available Funding Categories:

• Early Career Development Grants
• PLGA Research Grants
• General Research Grants
• Infrastructure and Resource Grants

Contact for Application Questions: Pediatric Brain Tumor Foundation
Email and phone available on curethekids.org/research/apply-for-funding