Fanconi Anemia Research Fund: Research Grant Awards

_NOTE: Investigators can submit an LOI on a project idea relevant to FARF’s research priorities at any time. Investigators will be notified within one month as to whether they have been selected to submit a full proposal. Investigators selected to submit full proposals will be emailed a full proposal application at that time. Full proposals must be submitted within two months of the LOI acceptance date._

Founded in 1989 by parents Lynn and David Frohnmayer, FARF has supported more than 260+ grants to more than 202 investigators worldwide. Over the last 33 years, our outstanding donors have enabled us to fund $33 million in research projects.

Research Priorities

The Fanconi Anemia Research Fund (FARF) seeks to fund interdisciplinary and translational research efforts that will lead to rapid discovery and development of therapies or strategies that treat, control, or cure Fanconi anemia (FA). Research proposals must address one or more of our research priorities:

• Top Priority:
  • To define the pathogenesis of cancers including head and neck and anogenital squamous cell carcinomas that affect persons with FA, and to develop strategies for early detection, prevention, treatment, and cure.
• Additional Priorities:
  • Novel Therapies
  • To develop ex vivo and in vivo gene therapy and gene editing technologies for FA.
  • Bone Marrow Failure
  • To identify factors predictive of bone marrow failure, myelodysplastic syndrome, and leukemia, and associated treatment for high-risk populations.
  • Manifestations of FA
  • To understand, prevent, and treat systemic, inflammatory, and aging manifestations of FA, including but not limited to: Fanconi Anemia Neurological Syndrome (FANS), endocrine and fertility issues.
  • Quality of Life
  • To identify practical and proactive management strategies that families and persons with FA can use to develop and maintain a high quality of life.
  • Data Analytics
  • To use data analytics to identify biomarkers, hypotheses, risk predictions, and treatment for FA.
  • Resource Sharing
  • To develop shared research resources and systems for allocation (i.e., tissue samples, cell lines, model systems, and data).

Investigators can apply for Research Grant Awards (RGA) which range from $25,000 – $250,000 for one- to two-year projects that address our research priorities. Projects may be pre-clinical or clinical in nature.  FCF seeks to fund innovative project ideas that have the potential to make significant impact on our understanding of the disease and clinical care for people with FA.

Eligibility

_You can learn more about this opportunity by visiting the funder's website._

• Researchers who hold a PhD, MD, or equivalent degree from both US and international academic, nonprofit, or for-profit institutions are invited to apply.
  • Researchers previously funded by FARF, or those new to the FA field, including assistant, associate, and full professors, are all encouraged to apply.
• FARF encourages early stage investigators - defined as an individual who has not received a FARF grant as a principal investigator OR is within their first five years of their first academic appointment at the level of Assistant Professor or the equivalent - to apply.
  • FARF encourages early stage investigators to collaborate with senior investigators who have demonstrated scientific productivity either in the Fanconi anemia field or in fields of particular relevance to Fanconi anemia pathology and molecular pathogenesis.
• There is no limit to the number of LOI an investigator is allowed to submit.

Ineligibility

• RGA grants do not cover indirect costs
• RGA grants cannot be used as startup funds for establishing new laboratories