Bow Foundation GNAO1 Research Grant Program

Geographic Scope: International (funded researchers in US, Switzerland, Netherlands, Italy)

Focus Areas:

• GNAO1-related neurodevelopmental disorders research
• Gene therapy development
• Drug discovery and treatment identification
• Clinical trials and preclinical research
• Mechanistic studies of GNAO1 mutations
• Patient registry and natural history studies

Disease Focus: GNAO1-related genetic disorders (rare neurological condition affecting ~400+ children and adults worldwide)

Background

The foundation has supported over $1 million in GNAO1 research as of 2025.

Disease Impact

Children with GNAO1 disorders experience:

• Severe developmental delays
• Seizures
• Uncontrolled muscle movements (dystonia, dyskinetic crises)
• Movement disorders
• Epilepsy

Grant Administration

As of 2023, the grant program is administered in partnership with the Orphan Disease Center at the University of Pennsylvania.

Eligibility

• Qualified independent investigators
• Academic and research institutions
• International researchers

Tax Information

• Tax ID: 82-1323389
• Status: IRS-recognized 501(c)(3) tax-exempt public charity

Application Process

Current Status: No open funding opportunity at this time (as of April 2026)

How to Apply

1. Visit the grant opportunities page at gnao1.org/grant-opportunities/
2. Check for open Request for Proposals (RFP)
3. Contact the foundation via their website for further information when opportunities become available

Required Information

• Specific details about application requirements are not publicly available
• Applicants should contact the foundation directly for:
  • Current funding opportunities
  • Application deadlines
  • Required submission materials
  • Specific eligibility criteria
  • Budget guidelines

Contact Method

Website Contact Form: gnao1.org (via "Contact Us" page)