Alpha-1 Foundation: John W. Walsh Career Development Grant

Alpha-1 Foundation: John W. Walsh Career Development Grant

Status: ACTIVE
Funder: Alpha 1 Foundation Inc
Amount: Up to US $300,000
Last Updated: December 26, 2025

Summary

The Alpha-1 Foundation's John W. Walsh Career Development Grant aims to foster careers in biomedical research for physician-scientists dedicated to Alpha-1 Antitrypsin Deficiency. This grant supports innovative research and training for junior physicians, encouraging the exploration of new hypotheses relevant to AATD. With funding of up to $100,000 over three years, it promotes collaboration and development in the field, emphasizing the importance of addressing clinical and ethical challenges in AAT research.

Overview

Alpha-1 Foundation Our Mission The Alpha-1 Foundation is committed to finding a cure for Alpha-1 Antitrypsin Deficiency and to improving the lives of people affected by Alpha-1 worldwide. Grants Awards Program The Grants Award Program is the Alpha-1 Foundation’s mechanism to fund a broad range of research that leads to improvements in the lives of people living with AAT Deficiency. Goals The specific goals of the Program are: to promote basic science and clinical research related to the alpha-1 antitrypsin protein and AAT Deficiency; to attract and train clinical researchers for the study of AAT Deficiency; to support and encourage established scientists to work on clinical problems and ethical, legal, and social issues within the field of AAT research (with a preference given to new investigators); and ultimately, to develop effective therapies for the clinical manifestations of AAT Deficiency. The Alpha-1 Foundation will support a broad spectrum of research projects involving basic science, translational and clinical research, and ethical, legal, and social issues. John W. Walsh Career Development The John W. Walsh Career Development Grant is aimed specifically at facilitating the establishment of a career in biomedical research for physician-scientists, is intended to continue his/her commitment to a cure through investment in the careers of junior physicians engaged in Alpha-1 research. Objective Encourage the development/testing of new hypotheses/new methods in AATD relevant research. Funding Up to $100,000 for a three-year period.

Eligibility

We've imported the main document for this grant to give you an overview. You can learn more about this opportunity by visiting the funder's website. Eligible InstitutionsApplicants are eligible to apply if their institution has any of the following characteristics:For-profit or non-profit organizationPublic or private institutions, such as universities, colleges, hospitals, and laboratoryUnits of State and local governmentEligible agency of the federal governmentDomesticForeignEligible InvestigatorEligible candidates for this award must have a clinical doctorate (including M.D., D.O., or equivalent) and must be practicing physicians. No more than 6 years may have elapsed since the first faculty appointment at the assistant professor level or equivalent (including instructor, research assistant professor, research scientist, staff scientist, etc) at the time of the award.Interruptions of work experience due to extenuating circumstances will be considered on a case-by-case basis. At the time of this award, the candidate must have a “full-time” faculty appointment at the applicant institution. The Alpha-1 Foundation requires that each applicant allocate $1,000 of the total budget to pay for travel to the Alpha-1 Foundation’s Biennial Investigators’ Meeting for the first year of the proposal’s period of performance. In case the applicant cannot attend the Investigators’ Meeting, the $1,000 budgetary line item is not refundable.

Ineligibility

Please note that the Alpha-1 Foundation does not accept LOIs or grant applications from pharmaceutical companies, biotechs, or industry for its in-cycle grants programs.  These entities may not be collaborators on any proposals.  Applicants who have already received an NIH K award (or equivalent career development award) or R-level grant award are not eligible to apply.Any individual who received an Alpha-1 Foundation Research Grant in the previous year’s grant cycle is not eligible to apply for an in-cycle grant in the current cycle. Major equipment may not be requested as part of a grant application, in accordance with Alpha-1 Foundation policies. Major equipment is defined as equipment that costs more than $500.The Alpha-1 Foundation does not pay for indirect costs, facilities and administrative costs or overhead costs.