The Stemler Family Foundation

The Darin and Lori Anderson Foundation

Irvine, CA

Samueli Foundation

Corona Del Mar, CA

The Samueli Foundation primarily funds community well-being and opportunity in Orange County, California, including education, food security, homelessness, and Jewish life in Orange County and Israel. Its 2024 grants ranged from $500 to nearly $9.7 million, with a median of about $39,500; open initiatives offer awards of $50,000–$100,000, up to $500,000, or up to $1 million, depending on the fund. It does not accept unsolicited requests for strategic grantmaking, but eligible organizations can apply to open initiatives during their application windows.

Edwards Lifesciences Foundation

Irvine, CA

Edwards Lifesciences Foundation funds charitable organizations improving access to care for underserved people with structural heart disease, as well as local health, education, economic opportunity, and basic-needs programs. Its 2024 grants ranged from $500 to $1,523,928, with a median of $7,500; it supports communities where Edwards employees live and work, with the largest share of recent funding going to California. It accepts requests through an annual online application cycle, usually opening in late spring.

Communities Foundation of Texas Inc

Dallas, TX

Communities Foundation of Texas funds charitable work in health, wealth, living, and learning, with much of its grantmaking supporting North Texas nonprofits; its 2025 grants had a median of $18,779, though award sizes varied widely. Nearly all opportunities are by invitation, and its Nonprofit Gateway profile is not a grant application.

The William Jeff and Jennifer Gross

Laguna Beach, CA

The William Jeff and Jennifer Gross supports nonprofits in healthcare, education and the arts, humanitarian relief and global development, the environment, and community services, with giving concentrated in New York and California but also reaching other states and international work. Its 2024 grants ranged from $2,500 to $3 million, with a median of $150,000. It does not accept unsolicited requests and gives only to preselected organizations.

C & R Newman Family Foundation

Encino, CA

The foundation funds organizations working in health, education, arts, youth programs, and human services, primarily in California. Its 2025 grants ranged from $500 to $1,061,000, with a median of $10,000. It gives only to preselected charities and does not accept unsolicited requests.

Penner Family Foundation Inc

Bentonville, AR

The foundation supports higher education and education, as well as work in mental health, employment, and health care. Its 2025 grants ranged from $1,000 to $8 million, with a median of $25,000; the largest shares went to organizations in California and Rhode Island. It does not accept unsolicited requests and gives only to preselected organizations.

Silicon Valley Community Foundation

Mountain View, CA

Silicon Valley Community Foundation funds work in areas such as housing, economic security, education, health, the environment, arts and culture, and civic engagement, with Community Action Grants supporting local, community-led organizations in San Mateo and Santa Clara counties. Its 2024 grants had a median of $51,716, though amounts varied widely; applications depend on the program, and SVCF states that it does not accept unsolicited proposals for advised funds.

California Community Foundation

Los Angeles, CA

The California Community Foundation funds work in education, health, housing, immigration, and other community needs, primarily in Los Angeles County. Its 2025 grants had a median of $50,000, though amounts varied widely; it does not accept unsolicited funding requests.

The William & Flora Hewlett Foundation

Menlo Park, CA

The William & Flora Hewlett Foundation funds education, climate and conservation, the arts, gender equity, governance, democracy, and philanthropy, with work in the San Francisco Bay Area, the U.S. West, nationally, and internationally. Its 2024 grants had a median of $150,000, though awards ranged from $50 to more than $11 million; it often provides long-term general operating support. It generally does not accept unsolicited requests, except through invited open processes.

Marin Community Foundation

Novato, CA

Marin Community Foundation funds equity-focused work, including affordable housing, homelessness, community resilience and power, and arts; its Buck Family Fund supports organizations serving Marin County, including those based elsewhere. Its 2025 grants had a median of $25,000 and ranged from $5,050 to $10 million; the profile does not state whether it accepts unsolicited requests.

Direct Relief

Santa Barbara, CA

Direct Relief funds community health centers, free and charitable clinics, educational institutions, and other organizations addressing health inequities, and provides medical supplies for healthcare facilities serving underserved communities and people affected by emergencies. Its 2025 grants ranged from $5,500 to $4.34 million, with a median of $100,000, supporting work across the U.S. and more than 80 countries. The available information does not state whether it accepts unsolicited grant requests.