The Shepherd Family Charitable

Enterprise Holdings Foundation

Saint Louis, MO

Enterprise Holdings Foundation supports nonprofits in health, education, arts, disaster relief, reforestation, hunger relief, and community equity, with an emphasis on organizations actively supported by Enterprise employees and their families. Its reported grants range widely: 2024 giving averaged about $7,700 across 9,499 grants, while the foundation also offers awards of up to $40,000; it supports communities where Enterprise operates worldwide. Unsolicited requests are accepted at any time, but eligible applications must be submitted by an Enterprise team member or their spouse or domestic partner on behalf of a nonprofit they actively support.

Aetna Foundation Inc

Hartford, CT

Aetna Foundation supported health and wellness, access to health care, and related community needs; its 2021 grants ranged from $5,000 to $1 million, with a median of $40,000, and went to organizations across multiple states, especially in D.C. and Connecticut. Its 2021 filing was marked final, so it appears to have ended or be winding down grantmaking; that filing said there were no restrictions on who could apply and pointed applicants to its website for application materials.

Duke Energy Foundation

Charlotte, NC

The Duke Energy Foundation funds workforce development, local economic development and recovery, disaster resilience, conservation, and economic opportunity in communities across North Carolina, South Carolina, Florida, Ohio, Kentucky, and Indiana. It reports more than $30 million in annual charitable grants; awards vary widely, with a 2024 median of $25,000, and applications of $20,000 or less are accepted on a rolling basis. Applicants should contact their local Foundation representative before applying.

McKesson Foundation Inc

Dallas, TX

McKesson Foundation supports healthcare access across the U.S. and Canada, focusing on cancer, healthcare workforce training, and emergency response, especially for vulnerable communities; local priorities include Atlanta, Columbus, Dallas-Fort Worth, Houston, Memphis, Montreal, Richmond, and Toronto. Its 2025 grants ranged from $10,000 to $2.47 million, with a median of $100,000. Its filing says it does not accept unsolicited requests, while its current website describes online applications: up to $25,000 year-round and larger requests from February 1 through April 30.

Bristol-Myers Squibb Foundation Inc

Princeton, NJ

The Bristol-Myers Squibb Foundation supports health-access initiatives for disproportionately affected populations, including cancer, blood disorders, brain health, and clinical-trial participation, in the United States and internationally. In 2024, its median grant was $134,090, though awards varied widely; it says application materials are available upon request and advises organizations to contact it about the process, but does not state whether unsolicited requests are accepted.

Gannett Foundation Inc

New York, NY

Gannett Foundation’s 2025 grants supported a range of organizations, with listed awards generally between $1,500 and $2,500, though the available figures do not establish a typical grant size or geographic focus. The foundation has wound down: its 2026 filing reports no grants or assets, and no current application process or acceptance of unsolicited requests is stated.

United Way of Greater Philadelphia and Southern New Jersey

Philadelphia, PA

United Way of Greater Philadelphia and Southern New Jersey funds nonprofits working to reduce poverty and expand opportunity, including programs in basic needs, financial stability, early learning, career pathways, and community resilience. Its 2025 grants ranged from $6,000 to $1,588,855, with a median grant of $60,000, for work in four southeastern Pennsylvania and five Southern New Jersey counties. The profile does not state whether it accepts unsolicited requests.

United Way Worldwide

Alexandria, VA

United Way Worldwide supports community-focused work in health, youth opportunity, financial security, resilience, disaster recovery, education, and human services, including local United Way organizations. Its 2024 grants ranged from $5,100 to $736,333, with a median of $22,675, and went to recipients across multiple U.S. states; it describes its broader reach as global. No application process for unsolicited grant requests is specified.

Synchrony Foundation

Stamford, CT

In 2024, Synchrony Foundation supported charitable organizations across workforce development, education, financial assistance, and giving, with grants ranging from $150 to $2.6 million and a median of $10,000. Its largest shares of grant funding went to Connecticut, New York, and South Carolina, followed by the District of Columbia and New Jersey; it does not accept unsolicited requests and funds preselected organizations only.

The Yelp Foundation

San Francisco, CA

The Pittsburgh Foundation

Pittsburgh, PA

The Pittsburgh Foundation funds basic needs, racial equity and social justice, environmental action, arts and culture, and economic mobility, primarily for organizations located in or serving Allegheny County, Pennsylvania. Its 2024 grants had a median of $18,576, though awards varied widely; the profile does not state whether it accepts unsolicited requests.