The GPCR Institute
The GPCR Institute is based in San Marcos, California. It manages the GPCR Consortium, which conducts research focused exclusively on G protein-coupled receptors (GPCRs). In its 2025 IRS filing, the Institute said its function had been fulfilled, its activities had substantially concluded, and it had begun shutting down.
The GPCR Institute at a glance
- Total assets
- $153,616
- -9.4% vs 2024
- Expenses (2025)
- $16,000
- -92.2% vs 2024
- Latest 990 filing
- Form 990-EZ, 2025 View filing
Data from IRS Form 990-EZ, 2025; updated September 2026.
How to apply to The GPCR Institute
- Contact
Mailing address: 310 S Twin Oaks Vly Rd 107-364, San Marcos, CA 92078
Phone: (858) 254-7116
Application details from Grantable's research on the foundation's public materials; confirm on its website before applying.
Who The GPCR Institute funds
Giving History
Giving Over Time
Total grant dollars and number of grants per year
From 2020 to 2021, annual grant giving ranged from $656K (2020) to $990K (2021). In 2021 it reported $990K in grants paid, as a total without an itemized list.
Hatched bars: grants paid as reported on the IRS filing, which lists no individual grants for that year.
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Financial History
Multi-year comparison from IRS filings
| Filing year | Total Assets | Revenue | Expenses | Grants paid | Grants |
|---|---|---|---|---|---|
| 2025 | $153,616 | — | $16,000 | — | — |
| 2024 | $169,616 | — | $205,519 | — | — |
| 2023 | $375,135 | — | $9,065 | — | — |
| 2022 | $384,200 | — | $602,109 | — | — |
| 2021 | $1,290,580 | — | $1,170,960 | $989,579 | Total only |
| 2020 | $3,484,701 | $625,061 | $1,547,668 | $656,437 | 1 |
"Total only": grants paid as reported on the IRS filing, which lists no individual grants for that year.
Research compiled by Grantable AI from public sources. Last updated September 2026.
Mission & Focus Areas
The Institute’s stated mission is to manage the GPCR Consortium, which conducts science research activities focused exclusively on GPCRs. The filing notes that GPCRs are important to pharmaceutical and biotechnology research and development efforts. It says the Institute recruited a membership base and organized, planned, and granted research projects with multiple research facilities.
Grantmaking
The IRS filing reports no grants in 2023, 2024, or 2025. It does not identify grant recipients, grant amounts, typical grant size, application procedures, or deadlines.
Leadership & Key People
Leadership team and compensation from IRS filings
The officers and directors listed on the 2025 filing are Maria Orencia, President and Director; James Schmidt, CFO; Jun Yoon, Director and Chairman of the Board; and Angela Walker, Director, Treasurer, and Secretary.
The GPCR Institute is led by Maria Orencia, President & Director on every filing since 2020; none of the 4 officers listed in 2025 report compensation.
Officers on the 2025 filing
Maria Orencia
President & Director
On filings since 2020
0.1 hrs/week
$115K (2020) → $0 (2025)
Jun Yoon
Director & Chairman of the Board
On filings since 2020
0.1 hrs/week
No compensation reported
Angela Walker
Director, Treasurer & Secretary
On filings since 2020
0.1 hrs/week
No compensation reported
James Schmidt
CFO
On filings since 2020
0.1 hrs/week
$16K (2020) → $0 (2025)
Data from IRS Form 990 filings, 2020–2025. "On filings since" is the earliest filing we hold that lists the person; hours are average hours per week as reported.
Compensation Overview
From 2021 IRS filing
The highest reported compensation on the 2021 filing was $105K, to Maria Orencia (President, Director). 2 officers or directors reported compensation on that filing.
Frequently asked questions about The GPCR Institute
How large is The GPCR Institute?
The GPCR Institute reported $154K in total assets on its 2025 IRS Form 990-EZ.
What does The GPCR Institute fund?
The Institute’s stated mission is to manage the GPCR Consortium, which conducts science research activities focused exclusively on GPCRs. The filing notes that GPCRs are important to pharmaceutical and biotechnology research and development efforts. See mission & focus areas ↑
How do I apply for a grant from The GPCR Institute?
The GPCR Institute has no public application process in the sources Grantable reviewed. Contact the foundation directly before submitting a request.
What is The GPCR Institute's EIN?
The GPCR Institute's EIN (Employer Identification Number) is 47-1291331. IRS Form 990 filing data is available on this page for 2020–2025.
Data last updated September 2026. Sourced from IRS Form 990 filings. Research dossier generated September 2026.
Data update history
(7)
When this profile's IRS filing data changed on Grantable
- Updated Form 990 for fiscal year 2020 (received by the IRS August 23, 2022)
- Updated Form 990 for fiscal year 2021 (received by the IRS November 15, 2022)
- Updated Form 990-EZ for fiscal year 2022 (received by the IRS September 13, 2023)
- Updated Form 990-EZ for fiscal year 2023 (received by the IRS November 15, 2024)
- Updated Form 990-EZ for fiscal year 2024 (received by the IRS November 17, 2025)
- Added Form 990-EZ for fiscal year 2025 (received by the IRS August 2, 2026)
- IRS filings on file for fiscal years 2020–2024
Explore Open Grants
Browse active grant opportunities in The GPCR Institute's focus areas in our free grants database
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Figures come from The GPCR Institute's IRS filings (methodology). AI-written summaries, news items and logos are not covered by the open licence. Spot an error? Email hello@grantable.co.
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