The Craig and Vicki Brown Foundation

Enterprise Holdings Foundation

Saint Louis, MO

Enterprise Holdings Foundation supports nonprofits in health, education, arts, disaster relief, reforestation, hunger relief, and community equity, with an emphasis on organizations actively supported by Enterprise employees and their families. Its reported grants range widely: 2024 giving averaged about $7,700 across 9,499 grants, while the foundation also offers awards of up to $40,000; it supports communities where Enterprise operates worldwide. Unsolicited requests are accepted at any time, but eligible applications must be submitted by an Enterprise team member or their spouse or domestic partner on behalf of a nonprofit they actively support.

Duke Energy Foundation

Charlotte, NC

The Duke Energy Foundation funds workforce development, local economic development and recovery, disaster resilience, conservation, and economic opportunity in communities across North Carolina, South Carolina, Florida, Ohio, Kentucky, and Indiana. It reports more than $30 million in annual charitable grants; awards vary widely, with a 2024 median of $25,000, and applications of $20,000 or less are accepted on a rolling basis. Applicants should contact their local Foundation representative before applying.

John R & Hope Reese Foundation

Hobe Sound, FL

The foundation supports a range of charitable organizations, including community, education, historic preservation, and health care groups, with recent grants concentrated in Florida and New York and also reaching other states. In 2025, grants ranged from $500 to $9,000, with a median of $1,000. Its 2023 filing says it does not limit giving to preselected organizations and invites organizations to submit a letter describing their work.

The Jolley Foundation

Greenville, SC

The Jolley Foundation funds community-led work addressing the root causes and effects of poverty and discrimination, including racial and social justice, advocacy, capacity-building, and equitable economic development. Its primary focus is Greenville County, South Carolina; recent grants ranged from $1,555 to $150,000, with a median of $30,000.

United Way of Greenville County Inc

Greenville, SC

United Way of Greenville County funds multi-year grants to organizations addressing poverty through affordable housing, childcare, postsecondary education and job credentials, and transportation. Its 2024 grants ranged from $5,118 to $252,389, with a median of $35,000; funding focuses on organizations serving Greenville County, South Carolina. The current grant cycle is closed, and the next is expected in 2026; the profile does not state whether unsolicited requests are accepted.

William Randolph Hearst Foundation

New York, NY

The William Randolph Hearst Foundation funds established U.S. nonprofits in culture, education, health, and social services, with an emphasis on broad reach, strong results, and sustainable programs. In 2024, grants ranged from $1,000 to $2 million, with a median of $100,000. It accepts applications through its grants portal and does not restrict giving to preselected organizations.

LPL Financial Foundation Inc

Boston, MA

Scansource Charitable Foundation

Greenville, SC

The foundation funds services for underrepresented children, PreK–12 education, and community-based family support, including children’s basic needs, family well-being, and education or workforce programs. Grants typically have a median of $3,750, though 2025 awards ranged from $150 to $50,000, for organizations serving communities in its listed U.S. footprint. It accepts online applications from eligible 501(c)(3) organizations; the application window is March 1–September 30.

Sisters of Charity Foundation of South Carolina

Cleveland, OH

The Sisters of Charity Foundation of South Carolina funds nonprofits and coalitions serving South Carolina, focusing on systems change in economic mobility and housing security, plus community engagement activities; health care systems change grants are by invitation only. Recent grants ranged from $5,500 to $100,000, with a median of $25,000; current Systems Change grants offer up to $75,000 annually for local or regional work or $100,000 for state-level work, while Community Engagement grants are up to $1,500. Systems Change Grants currently accept Letters of Intent through an inquiry process; unsolicited requests for health care grants are not accepted.

Seattle Children's Hospital

Seattle, WA

Seattle Children’s supports pediatric medical research, education, and programs that improve children’s health, including housing support; grants primarily go to research and medical organizations. In 2024, grants ranged from $5,147 to $9.5 million, with a median of about $58,000. Its Crossett Fund accepts unsolicited requests year-round for projects improving the health of children and adolescents in southeast Alaska, with awards up to $10,000.

Truist Foundation Inc

Orlando, FL

The foundation funds nonprofit work that advances economic mobility and opportunity, especially workforce and career pathways, small-business support, and community development for low-to-moderate-income and disadvantaged people. Grants reach communities along the East Coast through Texas; the 2024 median grant was $25,000, though awards varied widely. It accepts unsolicited requests through an online application, with annual cycle deadlines of March 31, July 31, and November 30.

Community Foundation of Western Pennsylvania and Eastern Ohio

Sharon, PA

The Community Foundation of Western PA & Eastern OH supports charitable programs in areas such as health, education, human services, arts, and community development. It serves Mercer and Lawrence counties in Pennsylvania and Trumbull County, Ohio; its 2024 grants had a median of $17,750, with amounts ranging from $5,050 to $609,507. It accepts unsolicited requests through a Letter of Intent, with full applications by invitation.