Jennie Edmundson Memorial Hospital Foundation

Gilbert M and Martha H Hitchcock Foundation

Omaha, NE

The foundation supports education, youth and family services, conservation, journalism, social services, and the arts, primarily in Nebraska, with some funding in Iowa and Virginia. Its 2025 grants ranged from $1,000 to $184,000, with a median of $15,000; it does not restrict giving to preselected organizations, but the filing does not say whether it accepts unsolicited requests.

American Heart Association Inc

Dallas, TX

The American Heart Association funds basic, clinical, behavioral, translational and population research on cardiovascular, cerebrovascular and brain health, along with research training and education programs. In 2025 it awarded 833 grants totaling about $198 million; amounts ranged from $5,000 to nearly $9.93 million, with a median of $20,000. Research awards are for eligible U.S.-based nonprofit institutions, and the profile describes a formal proposal process but does not state whether unsolicited requests are accepted.

Community Foundation for Western Iowa

Council Bluffs, IA

The Community Foundation for Western Iowa funds nonprofits and charitable projects in western and southwest Iowa, including work in community improvement, human services, education, youth, arts and culture, women’s well-being, and mental health and substance use. Its 2024 grants had a median of $15,000; Community Impact Grants for Pottawattamie County projects range from $500 to $5,000.

Community Fdn of Greater Des Moines F/K/a Greater Des Moines Community Fdn

Des Moines, IA

The Community Foundation of Greater Des Moines supports projects that improve quality of life in Greater Des Moines, including housing and transportation access, health, economic opportunity, inclusive communities, and nonprofit capacity-building. Its 2024 itemized grants had a median of about $12,900, though awards ranged from roughly $5,000 to $7.34 million.

Pella Rolscreen Foundation

Pella, IA

The Pella Rolscreen Foundation supports charitable organizations working in education and community betterment, including civic, cultural, social, and physical-environment programs in communities where Pella Corporation employees live. Large grants generally range from $10,000 to $50,000 and typically cover no more than 25% of project costs; its 2024 grants had a median of $1,029. It accepts unsolicited requests from eligible 501(c)(3) nonprofits and government entities in communities where Pella has manufacturing plants.

Prairie Meadows Race Track and Casino Inc

Altoona, IA

Prairie Meadows supports Iowa nonprofits in arts and culture, education, economic development, human services, and youth sports and recreation; Legacy grants focus on large-scale projects in central Iowa. Its programs offer $100–$1 million for Legacy, $100–$99,999 for Community Betterment, and $1,000–$50,000 for Youth Sports and Recreation. It accepts applications through its online system; the 2026 deadline was February 27, 2026, and has passed.

Iowa Health Care Association Foundation

West Des Moines, IA

The Iowa Health Care Association Foundation funds scholarships and career-education resources for employees of member long-term-care organizations and Iowa high school students pursuing long-term-care careers. Its typical giving level varies: it awarded 287 grants totaling about $4.1 million in 2024, and the listed high school scholarship is $2,000. Its programs focus on Iowa; the profile does not state whether it accepts unsolicited requests.

Quad Cities Community Foundation

Bettendorf, IA

Quad Cities Community Foundation funds nonprofit operations and programs across areas including education, health, arts and culture, community development, youth, and the environment, primarily in Rock Island County, Illinois, and Scott County, Iowa, with some service to surrounding counties. Its 2024 grants had a median of $15,000; its Operations and Programs Grants program lists requests of $5,000–$20,000.

Dupaco RW Hoefer Foundation

Dubuque, IA

The Dupaco RW Hoefer Foundation supports education, charitable work, and organizations or causes that enhance quality of life, with most 2025 grant dollars going to Iowa, followed by Florida, Wisconsin, and Illinois. Grants ranged from $100 to $100,000, with a median of $1,000. It directs applicants to a grant application form and says it does not restrict giving to preselected organizations.

New Charitable Foundation

Fort Dodge, IA

Ottumwa Regional Legacy Foundation Inc

Ottumwa, IA

The foundation funds community enrichment, nonprofit capacity building, health care, education, housing, and other priorities in Ottumwa and Wapello County, Iowa. Bright Ideas grants are typically $2,500–$30,000; 2024 grants ranged from $20 to $554,112. Its 2024 filing says it does not accept unsolicited funding requests and gives only to preselected organizations.

Community Foundation of Greater Dubuque

Dubuque, IA

It funds community needs across health, education, youth development, arts, social services, nonprofit capacity-building, and collaborative initiatives in a seven-county Eastern Iowa region, including through affiliate foundations. In 2024, its grants had a median of $13,500, with awards ranging from $5,020 to $1,292,499. The profile does not state whether it accepts unsolicited requests.