Illinois Public Health Institute

Enterprise Holdings Foundation

Saint Louis, MO

The Enterprise Holdings Foundation supports charitable and educational nonprofits in communities where Enterprise Mobility operates, focusing on health, education, arts, and disaster relief; applicants must be actively supported by an Enterprise Mobility team member, spouse, or domestic partner. Giving varies widely: it reported 9,499 grants in 2024, but its 2025 filing showed one grant of $101.4 million, so that amount is not a typical award. Applications are accepted at any time through eligible Enterprise-affiliated applicants; the Foundation does not limit giving to preselected organizations.

All Chicago Making Homelessness History

Chicago, IL

All Chicago funds Chicago-area homelessness and housing-stability services, including case management for provider organizations. In 2024, it made 51 grants ranging from $20,000 to $1,793,777, with a median of $196,915; all reported grant dollars went to Illinois recipients. The profile does not state whether it accepts unsolicited requests.

United Way Worldwide

Alexandria, VA

United Way Worldwide funds community programs focused on youth opportunity, health, financial security, education, and disaster relief, with 2024 grants made across multiple U.S. states and internationally. Its 209 reported grants ranged from $5,100 to $736,333, with a median of $22,675. It does not state whether it accepts unsolicited grant requests.

Visiting Nurse Association of Chicago

Chicago, IL

The VNA Foundation supports Chicago-area nonprofits providing home- and community-based health services to medically underserved people, with priorities including healthcare access, mental health, maternal and reproductive health, and organizational resiliency. Its 2025 grants ranged from $5,300 to $100,000, with a median of $50,000; it does not accept unsolicited requests for FY 2027, though eligible prior grantees may apply for renewals.

Blowitz-Ridgeway Foundation

Chicago, IL

The Blowitz-Ridgeway Foundation funds healthcare and homelessness services for low-income and underserved people in Chicago and suburban Cook County, with a focus on healthcare access and housing support. Recent grants were typically $10,000–$20,000, with a median of $15,000. It uses a letter-of-intent process, but applications from new organizations are paused through September 2026 and are expected to reopen in October 2026.

Cuore e Mani Foundation

Wilmington, DE

Cuore e Mani Foundation supports housing stability, homelessness prevention and services, affordable housing, and related advocacy, primarily in Illinois and California, especially Chicago and San Diego. Its 2024 grants ranged from $1,000 to $61,000, with a median of $7,500. It awards grants by invitation and does not accept unsolicited requests.

United Way of Metropolitan Chicago Inc

Chicago, IL

United Way of Metropolitan Chicago funds nonprofits addressing basic needs and community priorities such as health care, housing, food assistance, early learning, workforce development, and legal services across greater Chicago, including targeted support for Chicago’s South and West Sides and south suburbs. In 2025, grants ranged from about $5,000 to $2 million, with a median of $25,000. The stated 2026 Impact Grants process was limited to current partners, and the BridgeBuilders application was closed; no open unsolicited application process is stated.

University of Chicago

Chicago, IL

The University of Chicago primarily funds education and research, including instruction, scholarships, fellowships, and related services; its grants also support universities and research organizations. Its 2025 grants ranged from $5,182 to $8.85 million, with a median of about $161,000, and Illinois received the largest share of funding. It does not describe general unsolicited requests; specific opportunities use internal selection or application processes, and the Women’s Board accepts proposals from eligible university-affiliated applicants.

Bristol-Myers Squibb Foundation Inc

Princeton, NJ

The Bristol-Myers Squibb Foundation supports health access and stronger health systems, with a focus on adult and pediatric cancers, blood disorders, brain health, and clinical-trial participation in the United States, Brazil, India, and ten Sub-Saharan African countries. In 2024, its median grant was about $134,000, though awards varied widely; it does not state whether it accepts unsolicited requests, and advises prospective applicants to contact the Foundation about its process.

George M Eisenberg Foundation

Arlington Heights, IL

The foundation supports 501(c)(3) organizations in areas including health care, disability services, youth services, and hunger relief, with most 2024 grant dollars going to Illinois and the rest to Minnesota. Its 2024 grants had a median of $5,000, though awards ranged from $1,000 to $1,275,000. It accepts requests by letter rather than a formal application; requests are due by April 30 for consideration the following calendar year.

AT&T Foundation

Dallas, TX

The Chicago Community Trust

Chicago, IL

The Chicago Community Trust funds eligible nonprofits working to narrow the wealth gap and meet urgent needs, with priorities including economic mobility, education, jobs, homeownership, and community development in metropolitan Chicago and Cook County. Its 2025 grants had a median of $26,500, though amounts varied widely; the profile does not state whether it accepts unsolicited requests.