Cure Mito Foundation

PKD Foundation

Kansas City, MO

The PKD Foundation funds PKD-related research, care-team services, education, and patient support, primarily through grants to U.S. universities, medical centers, and research institutes; it also gives special consideration to some research partnerships in Canada and Australia. Recent grants typically had a median award of $70,000, while research grants are structured at $120,000 per year for two years; applicants may submit a pre-application, but only invited applicants can submit a full research application.

The Parent Project for Muscular Dystrophy Research Inc

Washington, DC

PPMD funds research and therapy development for Duchenne and Becker muscular dystrophy, along with related care, education, advocacy, and research infrastructure. In 2025, grants ranged from $7,500 to $300,000, with a median of $27,100; it accepts unsolicited applications through its ad hoc Investigator Award opportunity for eligible research. Its profile identifies it as Washington, DC-based but does not specify geographic limits for awards.

Flinn Foundation

Phoenix, AZ

The Flinn Foundation funds Arizona bioscience research and infrastructure, university scholarships, and arts-and-culture organizations; its civic-leadership work does not currently make grants. Its 2024 grants had a median of $33,000, though amounts varied widely. Bioscience grants are primarily by invitation, but eligible teams and early-stage companies can apply to specified programs.

The Leona M and Harry B Helmsley

New York, NY

Helmsley funds health research, care, facilities, and technology focused on Crohn’s disease, Type 1 diabetes, rural healthcare, Israel, vulnerable children in Sub-Saharan Africa, and New York City, with some programs reaching beyond those places. In 2025, its grants ranged from $3,157 to $6,966,024, with a median of $396,866. It does not accept unsolicited requests; organizations generally apply only after an invitation.

The Preuss Foundation Inc

La Jolla, CA

Institute for Advanced Clinical Trials for Children

North Bethesda, MD

To function as a nonprofit educational, scientific and research organization to enable and advance pediatric clinical research prescribed by regulation through:

Alzheimers Disease Data Initiative Inc

Kirkland, WA

Alzheimer's Disease Data Initiative is a coalition of leading academic, advocacy, government, industry, and philanthropy organizations that recognizes the need for dementia researchers to find easier ways to share data, analytical tools, and scientific findings. These partners are working together to accelerate progress towards new diagnostics, treatments, and cures for Alzheimer's disease and related dementias. Learn more atwww.alzheimersdata.org.

Friedreich's Ataxia Research Alliance

Springfield, VA

FARA funds basic, translational, and clinical research aimed at treatments and a cure for Friedreich’s ataxia, including disease mechanisms, cardiac research, and drug development. It supports eligible researchers and organizations worldwide; its 2024 grants had a median of about $121,000, while specific awards generally allow up to $125,000–$200,000 per year.

The Michael J Fox Foundation for Parkinson's Research

New York, NY

The Michael J. Fox Foundation funds basic, translational, and clinical research to advance a cure for Parkinson’s disease and improve treatments, supporting researchers in the United States and internationally. Its 2025 grants had a median award of about $426,000, though amounts varied widely. It generally does not accept unsolicited proposals; applications are submitted through its grant portal for designated funding opportunities.

Gates Foundation

Seattle, WA

The Gates Foundation funds work to reduce disease and poverty, improve health and gender equality in lower-income countries, and support education and economic mobility in the United States, especially Washington State; it works in more than 140 countries. Its 2024 grants had a median of $500,000, with awards ranging from $1 to $350.5 million. It generally does not accept unsolicited proposals, but periodically offers opportunities through published requests for proposals.

Communities Foundation of Texas Inc

Dallas, TX

Communities Foundation of Texas funds a broad range of community needs, including health, education, housing, and community development, primarily in North Texas and across Texas. Its 2025 grants had a median of about $18,800, though amounts varied widely; nearly all opportunities are by invitation, with some specific programs open for applications.

Greater Houston Community Foundation

Houston, TX

The Foundation makes grants through donor-advised and other donor-established funds for public benefit, human services, education, and health, including initiatives addressing economic mobility and poverty in Harris County. In 2024, its median grant was $25,000; it serves Greater Houston, while grants also go to recipients elsewhere in Texas and beyond. It does not accept proposals for the upcoming High-Impact Grantmaking cycle and plans to invite selected organizations or collaboratives to apply.