Challenge to Conquer Cancer

Scansource Charitable Foundation

Greenville, SC

The foundation funds services for underrepresented children, PreK–12 education, and community-based family support, including children’s basic needs, family well-being, and education or workforce programs. Grants typically have a median of $3,750, though 2025 awards ranged from $150 to $50,000, for organizations serving communities in its listed U.S. footprint. It accepts online applications from eligible 501(c)(3) organizations; the application window is March 1–September 30.

Alicia Watchorn Snyder Foundation Inc

Vero Beach, FL

The Stringer Foundation

Anderson, SC

Fred Collins Foundation

Simpsonville, SC

The Fred Collins Foundation supports charitable organizations working in areas including arts, community services, health, and education, with nearly all its 2024 giving directed to South Carolina. Its 12 grants ranged from $2,500 to $200,000, with a median of $8,500; it funds only preselected organizations and does not accept unsolicited requests.

United Way of Greenville County Inc

Greenville, SC

United Way of Greenville County funds multi-year grants to organizations addressing poverty through affordable housing, childcare, postsecondary education and job credentials, and transportation. Its 2024 grants ranged from $5,118 to $252,389, with a median of $35,000; funding focuses on organizations serving Greenville County, South Carolina. The current grant cycle is closed, and the next is expected in 2026; the profile does not state whether unsolicited requests are accepted.

American Association of Hip & Knee

Rosemont, IL

AAHKS funds hip and knee care research, professional education, and fellowship programs, including grants for adult reconstruction fellowships and North American arthroplasty studies. Its 2024 grants were typically $13,800 each; related FARE research grants offer up to $50,000. Awards have gone to organizations across the U.S., while FARE supports studies in North America; the profile describes an application process for FARE but does not state whether AAHKS accepts unsolicited requests.

Baker and Baker Foundation Inc

Columbia, SC

American Cancer Society Inc

Atlanta, GA

The American Cancer Society funds cancer research, patient support, advocacy, and related programs, with research support available to institutions across the United States. Its 2025 grants ranged from $5,648 to $9.6 million, with a median of $15,000. It accepts applications for research grants through specific programs and ProposalCentral; the profile does not state whether it accepts unsolicited requests for other funding.

Medicinal Whiskey Charity Inc

Greenville, SC

Fighting childhood illness with the power and passion of whiskey enthusiasts.

The Etnyre Foundation

Oregon, IL

The Etnyre Foundation funds nonprofit education, environmental, and health and well-being initiatives that benefit communities where Etnyre International operates. Its typical 2025 grant was about $4,800, with awards ranging from $1,615 to $23,680; most funding went to Illinois, with grants also made in several other states. It accepts applications annually from February 1 through 28.

Prisma Health Midlands Foundation

Columbia, SC

To promote awareness of prisma health's programs and services and to strengthen the quality of healthcare for the people served by prisma health through the use of the highest standards of philanthropy.

Central Carolina Community

Columbia, SC

Central Carolina Community funds education, human services, health, arts and culture, community development, disaster relief, and nonprofit capacity-building, primarily in the 11-county Midlands region of South Carolina, with some statewide and national grantmaking. Its 2025 grants had a median of $20,000; eligible nonprofits may apply through the online portal during published grant periods, though some opportunities are invitation-only.