Planning, organizing, and conducting fundraising activities and events to distribute funds to benefit pediatric cancer research.
Key facts about Caroline Symmes Inc
In short: Caroline Symmes Inc gave $250K across 3 grants in 2025 (avg $83K), mostly in Pennsylvania. Source: 2025 IRS Form 990.
- EIN
- 46-5643329
- Latest 990 filing
- Form 990, 2025
- Annual giving (2025)
- $250,000
- Grants made (2025)
- 3
- Average grant
- $83,333
- Median grant
- $25,000
- Total assets
- $265,506
- Primary geography
- Pennsylvania (80% of itemized 2025 grant dollars)
Data from IRS Form 990, 2025; updated September 2026.
Financial Overview
From 2025 IRS Form 990 · View filing
Total Assets
$266K
-5.9% YoY
Annual Giving
$250K
+0.0% YoY
Grant Count
3
-25.0% YoY
Avg Grant Size
$83K
+33.3% YoY
How Caroline Symmes Inc gives
- Giving held roughly steady from 2022 to 2025 (−17%). Method
From the foundation's IRS Form 990 filings. Methodology.
About Caroline Symmes Inc
Based on IRS filings
Caroline Symmes Inc is a public charity focused on Medical Research, based in Carmel, IN. IRS filing data is available from 2020 through 2025. As of 2025, the organization holds $266K in total assets. In 2025, it awarded 3 grants totaling $250K. Net investment income was $8K.
Focus Areas
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Geographic Focus
Where this funder awards grants
Grant Distribution by State
Share of 2025 grant dollars across all 3 itemized grants.
Cities
Giving Over Time
Total grant dollars and number of grants per year
From 2020 to 2025, annual grant giving ranged from $250K (2024) to $600K (2020). In 2025 it made 3 grants totaling $250K.
Grant Insights
How this funder distributes its grants
Top Recipients
Top 3 recipients in 2025
The largest 2025 recipient was The Children's Oncology Group Foundation Inc ($200K). Together the top 3 received $250K.
Grant Size Distribution
10 grants across all recorded years
The most common grant size was under $50K: 4 grants of 10 (40%).
Giving History
Grant recipients and amounts by year
| Recipient | Purpose | Amount |
|---|---|---|
| The Children's Oncology Group Foundation Inc Philadelphia, PA | Project Every Child is an initiative serving as a comprehensive registry and biobank for children, adolescents, and young adults with cancer. It enables researchers to link clinical data with tumor biospecimens, supporting precision medicine and improving treatment for common and rare cancers. The project aims to collect biological samples and health information from every child (aged 26 and under) diagnosed with cancer at COG institutions to understand disease causes and improve care. It maintains a secure, large-scale database of clinical data and a biorepository of specimens, including tumor, blood, saliva, or tissue samples, collected at diagnosis, progression, or relapse. It helps determine patient eligibility for COG therapeutic clinical trials. Provides data for molecular characterization, aiding in the development of targeted therapies. | $200,000 |
| Pediatric Cancer Research Foundation Irvine, CA | Our grant helped to fund pioneering research and continued to build the pipeline of pediatric oncology professionals. | $25,000 |
| Indiana University Foundation Ampath Global Pediatric Oncology and Hematology Fund Bloomington, IN | Donation by the Teen Board used in Dr. Vik's Ampath lab. Ampath Kenya is a partnership between Moi University, Moi Teaching and Referral Hospital, the AMPATH Consortium of universities around the world led by Indiana University and the Kenyan Government. Together, they work to build holistic, sustainable health in Kenya and around the world. | $25,000 |
Financial History
Multi-year comparison from IRS filings
| Metric | 2025 | 2024 | 2023 |
|---|---|---|---|
| Total Assets | $265,506 | $282,113 | $316,570 |
| Revenue | $335,667 | $290,676 | $389,037 |
| Expenses | $351,387 | $324,442 | $366,445 |
| Net Investment Income | $8,252 | $11,895 | $13,221 |
Data update history
When this profile's IRS filing data changed on Grantable
- Updated Form 990 for fiscal year 2022 (received by the IRS July 25, 2023)
- Updated Form 990 for fiscal year 2023 (received by the IRS July 22, 2024)
- Updated Form 990 for fiscal year 2024 (received by the IRS October 24, 2025)
- Updated Form 990 for fiscal year 2020 (received by the IRS November 12, 2021)
- Updated Form 990 for fiscal year 2021 (received by the IRS May 16, 2022)
- Added Form 990 for fiscal year 2025 (received by the IRS May 13, 2026)
- IRS filings on file for fiscal years 2020–2024
Leadership & Key People
Officers and directors from IRS filings
Caroline Symmes Inc is led by Elizabeth Symmes, President on every filing since 2020; 1 of 8 officers listed in 2025 is compensated.
Officers on the 2025 filing
Elizabeth Symmes
President
On filings since 2020
40 hrs/week
$8K (2024) → $46K (2025)
Andrew Thornton
Treasurer
Board Member → Treasurer, 2022
On filings since 2020
1 hr/week
No compensation reported
Brian Holmes
Vice President Science & Research
Board Member → Vice President Science & Research, 2022
On filings since 2020
1 hr/week
No compensation reported
David Symmes
Board Member
On filings since 2020
1 hr/week
No compensation reported
Emily Czarnecki
Board Member
On filings since 2022
1 hr/week
No compensation reported
Joseph Mervis
Vice President Media
On filings since 2022
5 hrs/week
No compensation reported
Ryan Drook
Board Member
On filings since 2022
1 hr/week
No compensation reported
Jason Cosgrove
Board Member
On filings since 2024
1 hr/week
No compensation reported
Former officers (3)
- Former: Joey Mervis (2020–2021) — Board Member
- Former: Jon Sinder (2020–2021) — Board Member
- Former: Tara Moore (2020–2021) — Board Member
Data from IRS Form 990 filings, 2020–2025. "On filings since" is the earliest filing we hold that lists the person; hours are average hours per week as reported.
Compensation Overview
From 2025 IRS filing
The highest reported compensation on the 2025 filing was $46K, to Elizabeth Symmes (President).
Frequently asked questions about Caroline Symmes Inc
How much does Caroline Symmes Inc give each year?
Caroline Symmes Inc gave $250K across 3 grants in 2025, according to its 2025 IRS Form 990. In 2024 it gave $250K across 4 grants.
What is Caroline Symmes Inc's typical grant size?
Caroline Symmes Inc's median grant in 2025 was $25,000, and its average grant was $83,333, across 3 grants on its 2025 IRS Form 990.
Where does Caroline Symmes Inc give grants?
Caroline Symmes Inc gives mostly in Pennsylvania: 80% of the grant dollars itemized on its 2025 IRS Form 990 went to recipients there. The next largest states were California (10%) and Indiana (10%).
Does Caroline Symmes Inc give general operating support?
Not in 2025: none of the 3 grants with a stated purpose on Caroline Symmes Inc's 2025 IRS Form 990 were described as general or operating support.
How large is Caroline Symmes Inc?
Caroline Symmes Inc reported $266K in total assets on its 2025 IRS Form 990. Its revenue that year was $336K.
What is Caroline Symmes Inc?
Caroline Symmes Inc is a public charity focused on Medical Research, based in Carmel, IN. It holds $266K in total assets as of 2025.
What is Caroline Symmes Inc's EIN?
Caroline Symmes Inc's EIN (Employer Identification Number) is 46-5643329. IRS Form 990 filing data is available on this page for 2020–2025.
Data last updated September 2026. Sourced from IRS Form 990 filings.
Here's the math on researching Caroline Symmes Inc by hand.
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