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Caroline Symmes Inc

Public charity · Grantmaker Carmel, IN EIN: 46-5643329 Website

Planning, organizing, and conducting fundraising activities and events to distribute funds to benefit pediatric cancer research.

Caroline Symmes Inc at a glance

In short: Caroline Symmes Inc gave $250K across 3 grants in 2025 (avg $83K), mostly in Pennsylvania. Source: 2025 IRS Form 990.

Annual giving (2025)
$250,000
+0.0% vs 2024
Grants made (2025)
3
-25.0% vs 2024
Average grant
$83,333
+33.3% vs 2024
Median grant
$25,000
Total assets
$265,506
-5.9% vs 2024
Primary geography
Pennsylvania (80% of itemized 2025 grant dollars)
Latest 990 filing
Form 990, 2025 View filing

Data from IRS Form 990, 2025; updated September 2026.

Who Caroline Symmes Inc funds

How this funder distributes its grants

Top Recipients

Top 3 recipients in 2025

The Children's Oncology Group Foundation Inc: $200KThe Children's Oncology GroupFoundation Inc$200KPediatric Cancer Research Foundation: $25KPediatric Cancer ResearchFoundation$25KIndiana University Foundation Ampath Global Pediatric Oncology and Hematology Fund: $25KIndiana University FoundationAmpath Global Pediatric…$25K

The largest 2025 recipient was The Children's Oncology Group Foundation Inc ($200K). Together the top 3 received $250K.

Grant Size Distribution

10 grants across all recorded years

4<$50K$50–100K3$100–250K3$250–500K$500K–1M$1–5M$5M+

The most common grant size was under $50K: 4 grants of 10 (40%).

Geographic Focus

Where this funder awards grants

Grant Distribution by State

5states

Share of 2025 grant dollars across all 3 itemized grants.

Cities

IndianapolisPhiladelphiaBloomingtonHollistonIrvineTampa

How Caroline Symmes Inc gives

  • Giving held roughly steady from 2022 to 2025 (−17%). Method

From the foundation's IRS Form 990 filings. Methodology.

Giving History

Giving Over Time

Total grant dollars and number of grants per year

$0$200K$400K$600K1 grant2020 1 grant2021 1 grant2022 1 grant2023 4 grants2024 3 grants2025

From 2020 to 2025, annual grant giving ranged from $250K (2024) to $600K (2020). In 2025 it made 3 grants totaling $250K.

Grants by year

Grant recipients and amounts by year

RecipientPurposeAmount
The Children's Oncology Group Foundation Inc Philadelphia, PAProject Every Child is an initiative serving as a comprehensive registry and biobank for children, adolescents, and young adults with cancer. It enables researchers to link clinical data with tumor biospecimens, supporting precision medicine and improving treatment for common and rare cancers. The project aims to collect biological samples and health information from every child (aged 26 and under) diagnosed with cancer at COG institutions to understand disease causes and improve care. It maintains a secure, large-scale database of clinical data and a biorepository of specimens, including tumor, blood, saliva, or tissue samples, collected at diagnosis, progression, or relapse. It helps determine patient eligibility for COG therapeutic clinical trials. Provides data for molecular characterization, aiding in the development of targeted therapies.$200,000
Pediatric Cancer Research Foundation Irvine, CAOur grant helped to fund pioneering research and continued to build the pipeline of pediatric oncology professionals.$25,000
Indiana University Foundation Ampath Global Pediatric Oncology and Hematology Fund Bloomington, INDonation by the Teen Board used in Dr. Vik's Ampath lab. Ampath Kenya is a partnership between Moi University, Moi Teaching and Referral Hospital, the AMPATH Consortium of universities around the world led by Indiana University and the Kenyan Government. Together, they work to build holistic, sustainable health in Kenya and around the world.$25,000
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Financial History

Multi-year comparison from IRS filings

Figures from IRS filings, by filing year
Filing yearTotal AssetsRevenueExpensesGrants paidGrantsNet Investment Income
2025$265,506$335,667$351,387$250,0003$8,252
2024$282,113$290,676$324,442$250,0004$11,895
2023$316,570$389,037$366,445$300,1071$13,221
2022$290,289$405,639$370,120$300,0001$694
2021$254,770$457,374$394,980$300,0001$160
2020$192,376$440,798$704,554$600,0001$344

About Caroline Symmes Inc

Based on IRS filings

Caroline Symmes Inc is a public charity focused on Medical Research, based in Carmel, IN. IRS filing data is available from 2020 through 2025. As of 2025, the organization holds $266K in total assets. In 2025, it awarded 3 grants totaling $250K. Net investment income was $8K.

Focus Areas

Leadership & Key People

Officers and directors from IRS filings

Caroline Symmes Inc is led by Elizabeth Symmes, President on every filing since 2020; 1 of 8 officers listed in 2025 is compensated.

Officers on the 2025 filing

  • Elizabeth Symmes

    President

    On filings since 2020

    40 hrs/week

    $8K (2024) → $46K (2025)

  • Andrew Thornton

    Treasurer

    Board Member → Treasurer, 2022

    On filings since 2020

    1 hr/week

    No compensation reported

  • Brian Holmes

    Vice President Science & Research

    Board Member → Vice President Science & Research, 2022

    On filings since 2020

    1 hr/week

    No compensation reported

  • David Symmes

    Board Member

    On filings since 2020

    1 hr/week

    No compensation reported

  • Emily Czarnecki

    Board Member

    On filings since 2022

    1 hr/week

    No compensation reported

  • Joseph Mervis

    Vice President Media

    On filings since 2022

    5 hrs/week

    No compensation reported

  • Ryan Drook

    Board Member

    On filings since 2022

    1 hr/week

    No compensation reported

  • Jason Cosgrove

    Board Member

    On filings since 2024

    1 hr/week

    No compensation reported

Former officers (3)
  • Former: Joey Mervis (2020–2021) — Board Member
  • Former: Jon Sinder (2020–2021) — Board Member
  • Former: Tara Moore (2020–2021) — Board Member

Data from IRS Form 990 filings, 2020–2025. "On filings since" is the earliest filing we hold that lists the person; hours are average hours per week as reported.

Compensation Overview

From 2025 IRS filing

Elizabeth Symmes — President: $46KElizabeth SymmesPresident$46K

The highest reported compensation on the 2025 filing was $46K, to Elizabeth Symmes (President).

Frequently asked questions about Caroline Symmes Inc

How much does Caroline Symmes Inc give each year?

Caroline Symmes Inc gave $250K across 3 grants in 2025, according to its 2025 IRS Form 990. In 2024 it gave $250K across 4 grants.

What is Caroline Symmes Inc's typical grant size?

Caroline Symmes Inc's median grant in 2025 was $25,000, and its average grant was $83,333, across 3 grants on its 2025 IRS Form 990.

Where does Caroline Symmes Inc give grants?

Caroline Symmes Inc gives mostly in Pennsylvania: 80% of the grant dollars itemized on its 2025 IRS Form 990 went to recipients there. The next largest states were California (10%) and Indiana (10%).

Does Caroline Symmes Inc give general operating support?

Not in 2025: none of the 3 grants with a stated purpose on Caroline Symmes Inc's 2025 IRS Form 990 were described as general or operating support.

How large is Caroline Symmes Inc?

Caroline Symmes Inc reported $266K in total assets on its 2025 IRS Form 990. Its revenue that year was $336K.

What is Caroline Symmes Inc?

Caroline Symmes Inc is a public charity focused on Medical Research, based in Carmel, IN. It holds $266K in total assets as of 2025.

What is Caroline Symmes Inc's EIN?

Caroline Symmes Inc's EIN (Employer Identification Number) is 46-5643329. IRS Form 990 filing data is available on this page for 2020–2025.

Data last updated September 2026. Sourced from IRS Form 990 filings.

Data update history

(7)

When this profile's IRS filing data changed on Grantable

  1. Updated Form 990 for fiscal year 2022 (received by the IRS July 25, 2023)
  2. Updated Form 990 for fiscal year 2023 (received by the IRS July 22, 2024)
  3. Updated Form 990 for fiscal year 2024 (received by the IRS October 24, 2025)
  4. Updated Form 990 for fiscal year 2020 (received by the IRS November 12, 2021)
  5. Updated Form 990 for fiscal year 2021 (received by the IRS May 16, 2022)
  6. Added Form 990 for fiscal year 2025 (received by the IRS May 13, 2026)
  7. IRS filings on file for fiscal years 2020–2024

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The filing figures on this page are open data under CC BY 4.0. About GrantGraph Open

Figures come from Caroline Symmes Inc's IRS filings (methodology). AI-written summaries, news items and logos are not covered by the open licence. Spot an error? Email hello@grantable.co.

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