Betty S Campbell Charitable

Duke Energy Foundation

Charlotte, NC

The Duke Energy Foundation funds workforce development, local economic development and recovery, disaster resilience, conservation, and economic opportunity in communities across North Carolina, South Carolina, Florida, Ohio, Kentucky, and Indiana. It reports more than $30 million in annual charitable grants; awards vary widely, with a 2024 median of $25,000, and applications of $20,000 or less are accepted on a rolling basis. Applicants should contact their local Foundation representative before applying.

Eastern Carolina Community Foundation

Florence, SC

Eastern Carolina Community Foundation supports nonprofits addressing needs such as youth development, mental health, violence prevention, food security, housing, and services for children, families, and seniors in seven Pee Dee counties in South Carolina. Its 2024 grants ranged from $5,200 to $50,000, with a median of $15,000; Community Impact requests are limited to $10,000, and Women in Philanthropy awards are up to $7,000. It offers an annual competitive application process; the profile does not state whether it accepts unsolicited requests outside these programs.

The First Bank Foundation

Cheraw, SC

Enterprise Holdings Foundation

Saint Louis, MO

Enterprise Holdings Foundation supports nonprofits in health, education, arts, disaster relief, reforestation, hunger relief, and community equity, with an emphasis on organizations actively supported by Enterprise employees and their families. Its reported grants range widely: 2024 giving averaged about $7,700 across 9,499 grants, while the foundation also offers awards of up to $40,000; it supports communities where Enterprise operates worldwide. Unsolicited requests are accepted at any time, but eligible applications must be submitted by an Enterprise team member or their spouse or domestic partner on behalf of a nonprofit they actively support.

Vyuha Inc

Miami Beach, FL

VYUHA INC supports a broad range of charitable work, including arts and culture, wildlife conservation, humanitarian aid, and health services, with grants across multiple states. Its 2025 grants ranged from $2,500 to $50,000, with a median of $15,000. It does not require an application form for consideration; eligible applicants must be public charities under IRC Sections 509(a)(1) or 509(a)(2).

Central Carolina Community Foundation

Columbia, SC

Central Carolina Community funds education, human services, health, arts and culture, community development, disaster relief, and nonprofit capacity-building, primarily in the 11-county Midlands region of South Carolina, with some statewide and national grantmaking. Its 2025 grants had a median of $20,000; eligible nonprofits may apply through the online portal during published grant periods, though some opportunities are invitation-only.

HM and Pearl Kyle Foundation Inc

Florence, SC

The foundation supports organizations addressing health care, basic needs, children and families, education, and community activities. Its 2024 grants ranged from $1,000 to $10,000, with a median of $7,500, primarily in South Carolina and also in North Carolina. It funds only preselected organizations and does not accept unsolicited requests.

Coastal Community Foundation of South Carolina Inc

N Charleston, SC

The Coastal Community Foundation of South Carolina funds nonprofits through competitive grants for areas including education, health, community development, arts, and human needs. Its 2024 grants had a median of $16,500, with awards ranging from $5,057 to $2.3 million, across nine coastal South Carolina counties. It accepts applications only for listed competitive programs, through its online portal.

Community Foundation of Greenville Inc

Greenville, SC

Community Foundation of Greenville funds nonprofits and projects in arts, education, environment, health, and human services, with a focus on Greenville County, South Carolina. Its 2026 Capacity Building Grants award $5,000–$12,500; 2024 grants had a median of $23,900. It accepts unsolicited requests through its Capacity Building Grants program.

South Carolina Christian Foundation

Spartanburg, SC

The foundation funds Christian ministries, churches, and quality-of-life organizations, with particular attention through its Community Trust Grants to Christian nonprofits in five South Carolina counties. Its 2024 grants had a median of $15,000, though awards varied widely; most grant dollars went to South Carolina, with additional funding in other states. Community Trust applicants must submit a Ministry Introduction Form and be invited to apply; the profile does not state whether other requests are unsolicited.

United Community Bank Foundation

Greenville, SC

United Community Bank Foundation funds economic empowerment, arts, housing and youth development in communities served across Alabama, Florida, Georgia, North Carolina, South Carolina and Tennessee. Its 2025 grants ranged from $250 to $16,000, with a median of $2,000. It does not accept unsolicited requests; grants go to preselected organizations.

Spartanburg County Foundation

Spartanburg, SC

The Spartanburg County Foundation funds nonprofits serving Spartanburg County residents, especially work advancing quality of life, education, economic mobility, and nonprofit capacity. Itemized grants had a median award of $15,500, though amounts varied widely; the information provided does not state whether it accepts unsolicited requests.