Alexian Brothers Health System

The Chicago Community Trust

Chicago, IL

The Chicago Community Trust funds nonprofits addressing economic mobility, wealth gaps, and urgent community needs, with priorities including homeownership, small businesses, education, quality jobs, and investment in underinvested communities. Its 2025 itemized grants had a median of $26,500, though awards vary widely; grants generally benefit Chicago-region residents, and the Trust directs applicants to open opportunities but does not state whether it accepts unsolicited requests.

United Way of Metropolitan Chicago Inc

Chicago, IL

United Way of Metropolitan Chicago funds nonprofit work on basic needs and community-led efforts, including healthcare, housing, food assistance, early learning, safety, legal services, and workforce development across greater Chicago and the surrounding region. Its 2025 grants ranged from $5,002 to $2,038,325, with a median of $25,000; the current Impact Grants cycle is closed to new applicants and limited to current partners, and the BridgeBuilders application is also closed.

Center for Housing and Health

Chicago, IL

The Center for Housing and Health funds homelessness-related programs, including housing and support services for people experiencing homelessness, with 2025 grants typically around $245,593 (median; awards ranged from $53,925 to $518,141). Its 2025 grants went to organizations in Illinois, including Chicago and Maywood; whether it accepts unsolicited requests is not stated.

Design Industries Foundation Fighting AIDS/Chicago Inc

Chicago, IL

The organization raises funds to award grants in support of chicago and Illinois metropolitan hiv/aids service agencies that provide direct service, preventative education and outreach to people who are hiv positive, living with aids or at risk for infection.

George M Eisenberg Foundation

Arlington Heights, IL

The George M Eisenberg Foundation funds social assistance, including health care, rehabilitation, disability services, and youth programs, with most 2024 grant dollars going to Illinois and the rest to Minnesota. Its 2024 grants ranged from $1,000 to $1,275,000, with a median of $5,000. It accepts requests from 501(c)(3) organizations by letter, due April 30 for consideration the following year.

Robert R McCormick Foundation

Chicago, IL

The Robert R. McCormick Foundation funds education, community development and economic opportunity, journalism and government accountability, and support for service members, veterans, and their families. It focuses community investments on Chicago’s South and West Sides, especially Englewood and Little Village, while also supporting initiatives across the region; its 2024 median grant was $50,000.

Howard Brown Health Center

Chicago, IL

Howard Brown Health Center provides a comprehensive array of healthcare and social services to a broad community. In addition to healthcare services, HBHC also conducts behavioral and clinical research in a variety of areas that impact wellness in the community.

American Heart Association Inc

Dallas, TX

The American Heart Association funds basic, clinical, behavioral, translational, population, and other research on cardiovascular, cerebrovascular, and brain health, mainly through research awards to eligible U.S.-based nonprofit institutions. In 2025, grants ranged from $5,000 to $9.9 million, with a median award of $20,000. Applications are submitted through designated programs; the profile does not state whether unsolicited requests are accepted.

Marjorie J Coller Private Fdn

Pennington, NJ

Everett D and Geneva V Sugarbaker

Saint Louis, MO

The Saint Louis-based foundation previously gave to preselected charitable organizations in Missouri, typically awarding about $12,000–$13,000 per grant in 2022 and 2023; its much larger 2024 grants established two foundations. It does not accept unsolicited requests, and its 2024 filing was marked final, with all assets distributed to the two foundations.

Westlake Health Foundation

Oakbrook Terrace, IL

Westlake Health Foundation funds health research, education, prevention, promotion, access, and direct care, including related community programs and capital projects, primarily in west suburban Cook County, especially Proviso Township. Its 2025 grants ranged from $5,000 to $1,784,000, with a median of $60,000. It accepts grant requests twice a year, with application receipt dates of May 1 and November 1.

Silicon Valley Community Foundation

Mountain View, CA

Silicon Valley Community Foundation funds work in areas such as housing, economic security, education, health, the environment, arts and culture, and civic engagement, with Community Action Grants supporting local, community-led organizations in San Mateo and Santa Clara counties. Its 2024 grants had a median of $51,716, though amounts varied widely; applications depend on the program, and SVCF states that it does not accept unsolicited proposals for advised funds.