Institute for Systems Biology

Nonprofit · Grant recipient Renton, WA EIN 91-2003593

Funding Overview

From IRS Form 990 filings · 2018–2025

Total received

$21.8M

Foundation funders

32

Grants recorded

112

Years covered

2018–2025

Who funds Institute for Systems Biology?

Institute for Systems Biology is funded by 32 grantmakers, led by Mayo Clinic Group Return ($2.7M), Gates Foundation ($2.5M), Seattle Children's Hospital ($2.3M). In total, IRS Form 990 filings record $21.8M in grants to Institute for Systems Biology between 2018–2025.

FunderTotal givenGrantsYears
Mayo Clinic Group Return$2,701,56242021–2024
Gates Foundation$2,542,78072020–2023
Seattle Children's Hospital$2,308,93772019–2025
Parker Institute for Cancer Immunotherapy$1,979,76042019–2022
Washington Research Foundation$1,933,392142019–2024
Sage Bionetworks$1,678,77362020–2024
William K Bowes Jr Foundation$1,399,99952020–2024
Cornell University$1,086,58152020–2024
President and Fellows of Harvard College$975,16252020–2024
Fred Hutchinson Cancer Research Center$900,11692019–2022
Phelps Family Foundation$850,00012021
Providence Health & Services - Washington$756,94022018–2022
Fred Hutchinson Cancer Center$446,08452022–2025
M J Murdock Charitable Trust$400,00022020
Every Cure Inc$309,02212024
The Washington STEM Center$262,34142020–2023
The Mark Foundation for Cancer Research (US) Ltd$243,24412019
Johns Hopkins University$210,40842019–2023
Bay Area Lyme Foundation$104,98312019
American Heart Association Inc$104,06012019
Northwestern University$81,87522023–2024
The Obrzut Ling Foundation Inc$80,00032019–2025
Global Lyme Alliance Inc$75,00012019
Pacific Northwest Research Institute$62,75012019
The Dean Witter Foundation$62,50032019–2025
Show all 32 funders

Funding over time

Grant dollars and counts received per year

$0$2M$4M$6M1 grant2018 20 grants2019 23 grants2020 16 grants2021 17 grants2022 16 grants2023 14 grants2024 5 grants2025

From 2018 to 2025, annual grant giving ranged from $15K (2018) to $5.0M (2021). In 2025 it made 5 grants totaling $373K.

What grants has Institute for Systems Biology received?

Individual grants from IRS Form 990 filings, newest first

YearFunderPurposeAmount
2025Fred Hutchinson Cancer CenterResearch Support/Subawards$186,871
2025Seattle Children's HospitalPEDIATRIC MEDICAL RESEARCH GRANT SUBAWARD$100,878
2025The Obrzut Ling Foundation IncGeneral & Unrestricted$60,000
2025The Dean Witter FoundationFOR THE SYSTEMS EDUCATION EXPERIENCES PROGRAM$12,500
2025Jones Family FoundationUNSPECIFIED CHARITABLE PURPOSE$12,500
2024Every Cure IncISB WILL CURATE, EVALUATE, AND INTEGRATE LARGE BIOMEDICAL DATASETS INTO EVERY CURE'S KNOWLEDGE GRAPH, FOCUSING ON DATA QUALITY AND ONTOLOGY HARMONIZATION. THEY WILL PERFORM MANUAL CURATION, CROSS-VALIDATION, AND DEVELOPMENT OF PROTOCOLS TO ENSURE RELIABLE DRUG, DISEASE, AND MOLECULAR ASSOCIATIONS. THEIR WORK ENSURES THE SPOKE DATABASE AND OTHER KEY SOURCES ARE INCORPORATED INTO A ROBUST COMPUTATIONAL FRAMEWORK FOR DRUG REPURPOSING.$309,022
2024Sage BionetworksCRI IMMUNE ATLAS 4 AND 5: PLATFORM FOR IMMUNE-ONCOLOGY RESEARCH AND DATA SHARING. EXCEPTIONAL LONGEVITY DATA MANAGEMENT AND COORDINATING CENTER, DESIGN AND PERFORM CROSS-PROJECT ANALYSIS FOCUSED ON HARNESSING SYSTEMS BIOLOGY-BASED TECHNIQUES, SUCH AS MULTI-OMIC DATA INTEGRATION, NETWORK ANALYSIS, MACHINE LEARNING, AND STATISTICAL MODELING, TO INVESTIGATE BOTH AGING AND DISEASE, AS WELL AS THE INTERPLAY BETWEEN THEM.$204,222
2024William K Bowes Jr FoundationNEW FACULTY SUPPORT$200,000
2024Washington Research FoundationISB: TECHNOLOGY COMMERCIALIZATION$200,000
2024President and Fellows of Harvard CollegeSPONSORED RESEARCH SUB-AWARD$141,250
2024Sage BionetworksEXCEPTIONAL LONGEVITY: PROVIDE SCIENTIFIC OVERSIGHT OF A WORKING GROUP CONDUCTING CROSS-PROJECT ANALYSES USING SYSTEMS BIOLOGY APPROACHES TO STUDY AGING, ALZHEIMERS DISEASE, AND THEIR INTERACTIONS.$114,897
2024Fred Hutchinson Cancer CenterRESEARCH SUPPORT/SUBAWARDS$110,341
2024Mayo Clinic Group ReturnSUPPORT CHARITABLE PURPOSE$74,577
2024Northwestern UniversitySupport of research activities$69,366
2024Seattle Children's HospitalPEDIATRIC MEDICAL RESEARCH GRANT SUBAWARD$53,152
2024Cornell UniversityResearch$43,931
2024Mayo ClinicSUPPORT CHARITABLE PURPOSE$19,130
2024Jones Family FoundationUNSPECIFIED CHARITABLE PURPOSE$2,500
2024The Pfizer Foundation IncVOLUNTEER PROGRAM$50
2023Gates FoundationDISCOVERY AND TRANSLATIONAL SCIENCES$484,233
2023Mayo Clinic Group ReturnSUPPORT RESEARCH PROGRAM$445,307
2023Sage BionetworksCRI Immune Atlas4: Platform for immune-oncology research and data sharing. Exceptional Longevity Data Management and Coordinating Center, design and perform cross-project analysis focused on harnessing systems biology-based techniques, such as multi-omic data integration, network analysis, machine learning, and statistical modeling, to investigate both aging and disease, as well as the interplay between them.$379,595
2023President and Fellows of Harvard CollegeSPONSORED RESEARCH SUB-AWARD$361,086
2023Seattle Children's HospitalPEDIATRIC MEDICAL RESEARCH GRANT SUBAWARD$349,566
2023Cornell UniversityResearch$343,541
2023William K Bowes Jr FoundationNEW FACULTY SUPPORT$200,000
2023Washington Research FoundationISB INNOVATOR AWARD PROGRAM$100,000
2023Fred Hutchinson Cancer CenterHUMAN BIOLOGY$80,672
2023The Washington STEM CenterLASER ALLIANCE PROGRAM$61,079
2023Fred Hutchinson Cancer CenterVACCINE AND INFECTIOUS DISEASE RESEARCH$59,000

Showing 30 most recent of 112 recorded grants.

Frequently Asked Questions

Who funds Institute for Systems Biology?

Institute for Systems Biology is funded by 32 grantmakers, led by Mayo Clinic Group Return ($2.7M), Gates Foundation ($2.5M), Seattle Children's Hospital ($2.3M). In total, IRS Form 990 filings record $21.8M in grants to Institute for Systems Biology between 2018–2025.

Who is Institute for Systems Biology's largest funder?

Mayo Clinic Group Return is the largest recorded funder of Institute for Systems Biology, with $2.7M across 4 grants (2021–2024).

How much grant funding has Institute for Systems Biology received?

IRS 990 filings record $21.8M in grants to Institute for Systems Biology across 112 grants from 32 funders between 2018–2025. Filings are published on a delay, so recent grants may not appear yet.

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